Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Karttunen, T. J. (Tuomo J.)"'
Autor:
Koivurova, O.-P. (Olli-Pekka), Koskela, R. (Ritva), Blomster, T. (Timo), Ala-Rämi, A. (Antti), Lumme, H. (Henri), Kettunen, O. (Olli), Hukkanen, J. (Janne), Karttunen, T. J. (Tuomo J.), Mäkinen, M. (Markus), Ronkainen, J. (Jukka), Syrjänen, K. (Kari)
Background/Aim: Prompted by the increasing demand of non-invasive diagnostic tools for screening of gastric cancer (GC) risk conditions, i.e., atrophic gastritis (AG) and Helicobacter pylori (Hp) infection, the GastroPanel® test (GP: biomarker panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::280a44a6bc9ce5c00fb60d7d83522167
http://urn.fi/urn:nbn:fi-fe202201051235
http://urn.fi/urn:nbn:fi-fe202201051235
Autor:
Nortunen, M. (Minna), Väkiparta, N. (Nina), Porvari, K. (Katja), Saarnio, J. (Juha), Karttunen, T. J. (Tuomo J.), Huhta, H. (Heikki)
The pathogenesis of gastroesophageal reflux disease (GERD) is not fully understood. It involves the activation of mucosal immune-mediated and inflammatory responses. Toll-like receptors (TLR) 2 and TLR4 are pattern-recognition receptors of the innate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::de9583ba1dea63b8ff697e52116cbb11
http://urn.fi/urn:nbn:fi-fe2021102752502
http://urn.fi/urn:nbn:fi-fe2021102752502
Autor:
Sirniö, P. (Päivi), Väyrynen, J. P. (Juha P.), Mutt, S. J. (Shivaprakash J.), Herzig, K.-H. (Karl-Heinz), Walkowiak, J. (Jaroslaw), Klintrup, K. (Kai), Mäkelä, J. (Jyrki), Karttunen, T. J. (Tuomo J.), Mäkinen, M. J. (Markus J.), Tuomisto, A. (Anne)
Systemic inflammation is a stage-independent marker of poor prognosis in colorectal cancer (CRC), activated in a complex, multifactorial process. It has been proposed that one of the main factors driving systemic inflammation may be tumor necrosis. K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::b644fa729c521f369386f253062f8452
http://urn.fi/urn:nbn:fi-fe2020082864577
http://urn.fi/urn:nbn:fi-fe2020082864577
Autor:
Söderström, H. K. (Henna K.), Räsänen, J. (Jari), Saarnio, J. (Juha), Toikkanen, V. (Vesa), Tyrväinen, T. (Tuula), Rantanen, T. (Tuomo), Valtola, A. (Antti), Ohtonen, P. (Pasi), Pääaho, M. (Minna), Kokkola, A. (Arto), Kallio, R. (Raija), Karttunen, T. J. (Tuomo J.), Pohjanen, V.-M. (Vesa-Matti), Ristimäki, A. (Ari), Laine, S. (Simo), Sihvo, E. (Eero), Kauppila, J. H. (Joonas H.)
Purpose: The Finnish National Esophago-Gastric Cancer Cohort (FINEGO) was established to combine the available registry data with detailed patient information to form a comprehensive, retrospective, population-based research platform of surgically tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::06a999743dc88af8e38ad352269ec5ec
http://urn.fi/urn:nbn:fi-fe202102124615
http://urn.fi/urn:nbn:fi-fe202102124615
Autor:
Patankar, M. (Madhura), Mattila, T. (Taneli), Väyrynen, J. P. (Juha P.), Klintrup, K. (Kai), Mäkelä, J. (Jyrki), Tuomisto, A. (Anne), Nieminen, P. (Pentti), Mäkinen, M. J. (Markus J.), Karttunen, T. J. (Tuomo J.)
Anoikis is a form of apoptosis induced when a cell loses contact with the extracellular matrix (ECM). Anoikis resistance is essential for metastasis formation, yet only detectable by in vitro experiments. We present a method for quantitation of putat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::5c025cd9a788e0fe516013d22f87c25a
http://urn.fi/urn:nbn:fi-fe2020063046398
http://urn.fi/urn:nbn:fi-fe2020063046398
Autor:
Kemi, N. (Niko), Eskuri, M. (Maarit), Ikäläinen, J. (Julia), Karttunen, T. J. (Tuomo J.), Kauppila, J. H. (Joonas H.)
Tumor budding has been associated with poor prognosis in several cancer types, but its significance in gastric cancer is unknown. The aim of this study was to assess the prognostic significance of tumor budding in gastric adenocarcinoma, and its main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::02bbb27bf7713ff5f84a028bb55d1c08
http://urn.fi/urn:nbn:fi-fe2019110737085
http://urn.fi/urn:nbn:fi-fe2019110737085
Autor:
Kemi, N. A. (Niko A.), Eskuri, M. (Maarit), Pohjanen, V.-M. (Vesa-Matti), Karttunen, T. J. (Tuomo J.), Kauppila, J. H. (Joonas H.)
Aims: Histological assessment of stromal maturity is a potential prognostic factor in colorectal cancer, but its applicability in gastric adenocarcinoma is completely unknown. The aim of this study was to evaluate the feasibility and prognostic signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::ea2fc7a0915caee8fba390876149c49a
http://urn.fi/urn:nbn:fi-fe2019110737086
http://urn.fi/urn:nbn:fi-fe2019110737086
Autor:
Sirniö, P. (Päivi), Väyrynen, J. P. (Juha P.), Klintrup, K. (Kai), Mäkelä, J. (Jyrki), Karhu, T. (Toni), Herzig, K.-H. (Karl-Heinz), Minkkinen, I. (Ilkka), Mäkinen, M. J. (Markus J.), Karttunen, T. J. (Tuomo J.), Tuomisto, A. (Anne)
Background: Cancer cachexia is a complex wasting syndrome affecting patients with advanced cancer, with systemic inflammation as a key component in pathogenesis. Protein degradation and release of amino acids (AAs) in skeletal muscle are stimulated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::b6a478873e91701ebf2396ead2a1ded0
http://urn.fi/urn:nbn:fi-fe202002216172
http://urn.fi/urn:nbn:fi-fe202002216172
Autor:
Väyrynen, J. P. (Juha P.), Tuomisto, A. (Anne), Väyrynen, S. A. (Sara A.), Klintrup, K. (Kai), Karhu, T. (Toni), Mäkelä, J. (Jyrki), Herzig, K.-H. (Karl-Heinz), Karttunen, T. J. (Tuomo J.), Mäkinen, M. J. (Markus J.)
Anemia is common in colorectal cancer (CRC) but its relationships with tumor characteristics, systemic inflammation, and survival have not been well characterized. In this study, blood hemoglobin levels and erythrocyte mean corpuscular volume (MCV) l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::77c948f480b6349815d038ab263eda66
http://urn.fi/urn:nbn:fi-fe201804096392
http://urn.fi/urn:nbn:fi-fe201804096392
Autor:
Kemi, N. (Niko), Eskuri, M. (Maarit), Herva, A. (Anni), Leppänen, J. (Joni), Huhta, H. (Heikki), Helminen, O. (Olli), Saarnio, J. (Juha), Karttunen, T. J. (Tuomo J.), Kauppila, J. H. (Joonas H.)
Background: Tumour microenvironment, including tumour–stroma ratio (TSR), might help identifying high-risk cancer patients. However, the significance of TSR in gastric cancer is unclear, especially in the intestinal and diffuse subtypes. The aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::4a52dabd0f8a6998c8b61f0600bc519d
http://urn.fi/urn:nbn:fi-fe2019110737084
http://urn.fi/urn:nbn:fi-fe2019110737084