Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kartika N, Shetty"'
In a feat of protein engineering alchemy, a FRET biosensor for tryptophan has been engineered into a direct biosensor for auxin, after a determined journey of over 2,800 steps to switch to a sensitivity appropriate for a plant hormone.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2359ee0db5118cb218b6f9be535aaa37
Autor:
Benjamin R, Bellenie, Kwai-Ming J, Cheung, Ana, Varela, Olivier A, Pierrat, Gavin W, Collie, Gary M, Box, Michael D, Bright, Sharon, Gowan, Angela, Hayes, Matthew J, Rodrigues, Kartika N, Shetty, Michael, Carter, Owen A, Davis, Alan T, Henley, Paolo, Innocenti, Louise D, Johnson, Manjuan, Liu, Selby, de Klerk, Yann-Vaï, Le Bihan, Matthew G, Lloyd, P Craig, McAndrew, Erald, Shehu, Rachel, Talbot, Hannah L, Woodward, Rosemary, Burke, Vladimir, Kirkin, Rob L M, van Montfort, Florence I, Raynaud, Olivia W, Rossanese, Swen, Hoelder
Publikováno v:
Journal of Medicinal Chemistry
Deregulation of the transcriptional repressor BCL6 enables tumorigenesis of germinal center B-cells, and hence BCL6 has been proposed as a therapeutic target for the treatment of diffuse large B-cell lymphoma (DLBCL). Herein we report the discovery o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b69bcc50adc7e246cbc1312a1fd83ac1
https://pubmed.ncbi.nlm.nih.gov/32275432
https://pubmed.ncbi.nlm.nih.gov/32275432
Publikováno v:
IUBMB Life. 65:633-644
Crystal structure analysis of a galactose-specific lectin from a leguminous food crop Dolichos lablab (Indian lablab beans) has been carried out to obtain insights into its quaternary association and lectin-carbohydrate interactions. The analysis led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d6fe973fa92b6951643f11bd19b7289
https://doi.org/10.1002/iub.1177
https://doi.org/10.1002/iub.1177
Autor:
Kartika N, Shetty, Vakada Lavanya, Latha, Rameshwaram Nagender, Rao, Siva Kumar, Nadimpalli, Kaza, Suguna
Publikováno v:
IUBMB life. 65(7)
Crystal structure analysis of a galactose-specific lectin from a leguminous food crop Dolichos lablab (Indian lablab beans) has been carried out to obtain insights into its quaternary association and lectin-carbohydrate interactions. The analysis led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a20f3e68eda24977e04052dc9e50342
https://pubmed.ncbi.nlm.nih.gov/23794513
https://pubmed.ncbi.nlm.nih.gov/23794513
Publikováno v:
Glycobiology. 22(1)
The crystal structure of a beta-prism II (BP2) fold lectin from Remusatia vivipara, a plant of traditional medicinal value, has been determined at a resolution of 2.4 A. This lectin (RVL, Remusatia vivipara lectin) is a dimer with each protomer havin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e989b1f94bb5e2fae4af52dcff5fc69c
https://pubmed.ncbi.nlm.nih.gov/21788359
https://pubmed.ncbi.nlm.nih.gov/21788359
Autor:
Tangavelou Karthikeyan, Kartika N. Shetty, Kaza Suguna, Subbiah Thamotharan, Kiran Kulkarni, Avadhesha Surolia, Mamannamana Vijayan
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 67(Pt 3)
A mutant of Erythrina corallodendron lectin was generated with the aim of enhancing its affinity for N-acetylgalactosamine. A tyrosine residue close to the binding site of the lectin was mutated to a glycine in order to facilitate stronger interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806d1b87b007d0a24d62213811ee4280
https://pubmed.ncbi.nlm.nih.gov/21358053
https://pubmed.ncbi.nlm.nih.gov/21358053