Production of proinflammatory mediators in activated microglia is synergistically regulated by Notch-1, glycogen synthase kinase (GSK-3β) and NF-κB/p65 signalling.

Autor: Cao, Qiong¹, Karthikeyan, Aparna¹ antlea@nus.edu.sg, Dheen, S. Thameem¹, Kaur, Charanjit¹, Ling, Eng-Ang¹

Publikováno v: PLoS ONE. 10/19/2017, Vol. 12 Issue 10, p1-18. 18p.

MiRNA-146a regulates the expression of tumor supportive genes in microglia associated with glioma

Autor: Dheen S. Thameem, Ling Eng Ang, Pardeshi Neelima, Karthikeyan Aparna

Publikováno v: Frontiers in Cellular Neuroscience. 10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c5baf0b198a954871f9e901b54d78116
https://doi.org/10.3389/conf.fncel.2016.36.00087

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Microglial SMAD4 regulated by microRNA-146a promotes migration of microglia which support tumor progression in a glioma environment.

Autor: Karthikeyan A; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Gupta N; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Tang C; Department of Research, National Neuroscience Institute, Singapore.; Duke-NUS Medical School, Singapore.; Division of Cellular and Molecular Research, National Cancer Centre, Singapore., Mallilankaraman K; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Silambarasan M; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Shi M; School of Biological Sciences, Nanyang Technological University, Singapore., Lu L; School of Biological Sciences, Nanyang Technological University, Singapore., Ang BT; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Duke-NUS Medical School, Singapore.; Department of Neurosurgery, National Neuroscience Institute, Singapore.; Singapore Institute for Clinical Sciences, ASTAR, Singapore., Ling EA; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Dheen ST; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Publikováno v: Oncotarget [Oncotarget] 2018 May 18; Vol. 9 (38), pp. 24950-24969. Date of Electronic Publication: 2018 May 18 (Print Publication: 2018).