Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Karthik Yadav Janga"'
Autor:
Akshaya Tatke, Narendar Dudhipala, Karthik Yadav Janga, Bhavik Soneta, Bharathi Avula, Soumyajit Majumdar
Publikováno v:
Pharmaceutics, Vol 11, Iss 4, p 158 (2019)
Delivering an effective drug load to the posterior section of the ocular tissues, while using a non-invasive technique, has always been a challenge. In this regard, the goal of the present study was to develop sustained release triamcinolone acetonid
Externí odkaz:
https://doaj.org/article/2a97b6b6cbf0428d9a729ceb11690214
Autor:
Akshaya Tatke, Narendar Dudhipala, Karthik Yadav Janga, Sai Prachetan Balguri, Bharathi Avula, Monica M. Jablonski, Soumyajit Majumdar
Publikováno v:
Nanomaterials, Vol 9, Iss 1, p 33 (2018)
Triamcinolone acetonide (TA), an intermediate acting corticosteroid, is used in the treatment of posterior ocular diseases, such as inflammation, posterior uveitis, and diabetic macular edema. The objective of this investigation was to prepare TA-loa
Externí odkaz:
https://doaj.org/article/c0ed33f523874c88bdc834714720de2f
Autor:
Suresh Bandari, Karthik Yadav Janga, Sandeep Sarabu, Narendar Dudhipala, Feng Zhang, Venkata Raman Kallakunta, Michael A. Repka
Publikováno v:
Eur J Pharm Biopharm
The current study is aimed at the development of chrono modulated multiple unit particulate systems (MUPS) of nifedipine (ND) by a continuous double extrusion process. ND, a poorly soluble drug was formulated into an amorphous solid dispersion (ASD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b002f18a97f33f64c94ddd08d2ad8127
https://doi.org/10.1016/j.ejpb.2021.08.014
https://doi.org/10.1016/j.ejpb.2021.08.014
Autor:
Venkata Raman Kallakunta, Narendar Dudhipala, Dinesh Nyavanandi, Sandeep Sarabu, Karthik Yadav Janga, Srinivas Ajjarapu, Suresh Bandari, Michael A. Repka
Publikováno v:
International Journal of Pharmaceutics. 641:123055
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9fb1b0e5c987ac1e8c33458528fd50e
https://doi.org/10.1016/j.ijpharm.2023.123055
https://doi.org/10.1016/j.ijpharm.2023.123055
Autor:
Monica M. Jablonski, Mohamed M. Ibrahim, Sai Prachetan Balguri, Karthik Yadav Janga, Doaa Nabih Maria, Soumyajit Majumdar, Narendar Dudhipala, Akshaya Tatke
Publikováno v:
J Pharmacol Exp Ther
Short precorneal residence time and poor transocular membrane permeability are the major challenges associated with topical ocular drug delivery. In the present research, the efficiency of the electrolyte-triggered sol-to-gel-forming system of natamy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8441a6bbe5cdcb5208b682827fac9571
https://doi.org/10.1124/jpet.119.256446
https://doi.org/10.1124/jpet.119.256446
Autor:
Srinivas Ajjarapu, Sandeep Sarabu, Michael A. Repka, Karthik Yadav Janga, Arun Butreddy, Suresh Bandari, Venkata Raman Kallakunta, S. Narasimha Murthy, Feng Zhang
Publikováno v:
AAPS PharmSciTech. 22
Fenofibrate is an effective lipid-lowering drug; however, its poor solubility and high log p (5.2) result in insufficient absorption from the gastrointestinal tract, leading to poor bioavailability. In this study, a one-step continuous twin-screw mel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabbe5588bdb3374e4bd83fc2767ed05
https://doi.org/10.1208/s12249-021-01945-8
https://doi.org/10.1208/s12249-021-01945-8
Publikováno v:
International journal of biological macromolecules. 167
Solid-state is the preferred choice for storage of protein therapeutics to improve stability and preserve the biological activity by decreasing the physical and chemical degradation associated with liquid protein formulations. Lyophilization or freez
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091366f601c68640b39bf4700f729d1b
https://pubmed.ncbi.nlm.nih.gov/33275971
https://pubmed.ncbi.nlm.nih.gov/33275971
Publikováno v:
AAPS PharmSciTech. 21
Lyophilization is a pivotal manufacturing process to obtain a stable drug product that is unstable as a ready-to-use formulation. Some formulations may require the addition of drug-specific excipients such as stabilizers, buffers, and bulking agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0933221870916cc23ae62ff0a3e749
https://doi.org/10.1208/s12249-020-01787-w
https://doi.org/10.1208/s12249-020-01787-w
Autor:
Monica M. Jablonski, Akshaya Tatke, XiangDi Wang, Bharathi Avula, Karthik Yadav Janga, Ikhlas A. Khan, Soumyajit Majumdar
Publikováno v:
AAPS PharmSciTech
The current research was undertaken to determine the existence and magnitude of P-glycoprotein (P-gp) expression on the blood-ocular barriers by studying the ocular penetration of loperamide, a specific P-gp substrate, in P-gp (Mdr1a) knock-out (KO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8c7d515e85461afb681dd2abb14769
https://doi.org/10.1208/s12249-018-0979-2
https://doi.org/10.1208/s12249-018-0979-2
Autor:
Sai Prachetan Balguri, Akshaya Tatke, Prakash Bhagav, Karthik Yadav Janga, Goutham R. Adelli, Soumyajit Majumdar
Publikováno v:
Journal of Pharmaceutical Sciences. 106:3515-3523
The objective of the present study was to evaluate the utility of melt-cast, topical, ocular inserts for delivery of drugs with different physicochemical properties. The model drugs tested include indomethacin (IN), ciprofloxacin hydrochloride, and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3065d6e20b7d068a34c69e4b4893d1e6
https://doi.org/10.1016/j.xphs.2017.07.017
https://doi.org/10.1016/j.xphs.2017.07.017