Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Karthik Sambath"'
Autor:
Venkatesan Perumal, Arun Reddy Ravula, Agnieszka Agas, Aakaash Gosain, Aswati Aravind, Ponnurengam Malliappan Sivakumar, Shanmuga Sundari I, Karthik Sambath, Sivakumar Vijayaraghavalu, Namas Chandra
Publikováno v:
Brain Sciences, Vol 13, Iss 3, p 402 (2023)
Traumatic brain injury (TBI) is a major source of death and disability worldwide as a result of motor vehicle accidents, falls, attacks and bomb explosions. Currently, there are no FDA-approved drugs to treat TBI patients predominantly because of a l
Externí odkaz:
https://doaj.org/article/992a62a40db046e6b9de8def1a6f9ce0
Autor:
Lauren Hutnik, Karthik Sambath, Kevin D. Belfield, Yuanwei Zhang, Xiangshan Liu, Zhaoxiong Wan
Publikováno v:
ChemPhotoChem. 5:317-325
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f4f40999fe1a9d0c27c06b2a4d87cc9
https://doi.org/10.1002/cptc.202000236
https://doi.org/10.1002/cptc.202000236
Autor:
Tinghan Zhao, Mehrun Nahar Uddin, Zhaoxiong Wan, Yuanwei Zhang, Shupei Yu, Karthik Sambath, Kevin D. Belfield
Publikováno v:
Chemistry – A European Journal. 27:247-251
Chemoresistance is one of the major challenges for cancer treatment, more recently ascribed to defective mitochondrial outer membrane permeabilization (MOMP), significantly diminishing chemotherapeutic agent-induced apoptosis. A boron-dipyrromethene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcafde0438c8e30c549b716163cf1d3
https://doi.org/10.1002/chem.202004278
https://doi.org/10.1002/chem.202004278
Autor:
Panče Naumov, Jeanette A. Krause, Ranaweera A. A. Upul Ranaweera, Stefan Schramm, Benjamin Duncan, Karthik Sambath, Durga Prasad Karothu, Anna D. Gudmundsdottir, Alexander Duncan, Dylan J. Shields
Publikováno v:
Journal of the American Chemical Society. 142:18565-18575
When exposed to UV light, single crystals of the vinyl azides 3-azido-1-phenylpropenone (1a), 3-azido-1-(4-methoxyphenyl)propenone (1b), and 3-azido-1-(4-chlorophenyl)propenone (1c) exhibit dramatic mechanical effects by cracking or bending with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70cb9ead252956c5d8b4ec0b62b20cbd
https://doi.org/10.1021/jacs.0c07830
https://doi.org/10.1021/jacs.0c07830
Publikováno v:
ChemPhotoChem
Acid-sensing ion channels (ASICs), present in both central and peripheral neurons, respond to changes in extracellular protons. They play important roles in many symptoms and diseases, such as pain, ischemic stroke and neurodegenerative diseases. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a46071926b007b6a4d066402e6ddc82
https://doi.org/10.1002/cptc.202000154
https://doi.org/10.1002/cptc.202000154
Publikováno v:
Organic Letters. 22:1208-1212
Photoacid generators (PAGs) are organic compounds that can generate protons (H+) upon irradiation with certain wavelengths of light. In this work, we designed and synthesized the first BODIPY-based PAGs with D-A and D-π-A conjugation structures and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1454768e712544371b22c35f6c5755
https://doi.org/10.1021/acs.orglett.0c00118
https://doi.org/10.1021/acs.orglett.0c00118
Autor:
Hitesh K. Agarwal, Radoslav Janicek, Jun Zhao, Karthik Sambath, Marcel Egger, Ernst Niggli, Graham C. R. Ellis-Davies
Publikováno v:
Chem Commun (Camb)
Monitoring and manipulation of ionized intracellular calcium concentrations within intact, living cells using optical probes with organic chromophores is a core method for cell physiology. Since all these probes have multiple negative charges, they m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8bdccac9b8e4a4577cb36c00f6fa21
https://europepmc.org/articles/PMC9502023/
https://europepmc.org/articles/PMC9502023/
Autor:
Dylan J, Shields, Durga Prasad, Karothu, Karthik, Sambath, Ranaweera A A Upul, Ranaweera, Stefan, Schramm, Alexander, Duncan, Benjamin, Duncan, Jeanette A, Krause, Anna D, Gudmundsdottir, Panče, Naumov
Publikováno v:
Journal of the American Chemical Society. 142(43)
When exposed to UV light, single crystals of the vinyl azides 3-azido-1-phenylpropenone (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a76eb553ed2574d3078a21cad570b062
https://pubmed.ncbi.nlm.nih.gov/32991156
https://pubmed.ncbi.nlm.nih.gov/32991156
Publikováno v:
Chemical communications (Cambridge, England). 55(94)
A new class of BODIPY-based oxime ester photo-uncaging group was designed to release carboxylic acids. The mechanism and kinetics of the photo-uncaging procedure were studied. Further, we constructed a photo-uncaging drug delivery system to release v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fbe20cf329c435ccbae48edb2321ad
https://pubmed.ncbi.nlm.nih.gov/31701102
https://pubmed.ncbi.nlm.nih.gov/31701102
Publikováno v:
ChemPhotoChem. 4:5319-5319
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30325b3550de94138482b4ac96262e3e
https://doi.org/10.1002/cptc.202000269
https://doi.org/10.1002/cptc.202000269