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pro vyhledávání: '"Karthik Raja Velmurugan"'
Autor:
Delasa Aghamirzaie, Karthik Raja Velmurugan, Shuchi Wu, Doaa Altarawy, Lenwood S. Heath, Ruth Grene
Publikováno v:
F1000Research, Vol 6 (2017)
Motivation: The increasing availability of chromatin immunoprecipitation sequencing (ChIP-Seq) data enables us to learn more about the action of transcription factors in the regulation of gene expression. Even though in vivo transcriptional regulatio
Externí odkaz:
https://doaj.org/article/cb83b3d0d09148e086ef813abdfd51e0
Publikováno v:
Molecular Genetics & Genomic Medicine
Background Fanconi anemia (FA) affects only one in 130,000 births, but has severe and diverse clinical consequences. It has been theorized that defects in the FA DNA cross‐link repair complex lead to a spectrum of variants that are responsible for
Publikováno v:
Oncogene
There remains a large discrepancy between the known genetic contributions to cancer and that which can be explained by genomic variants, both inherited and somatic. Recently, understudied repetitive DNA regions called microsatellites have been identi
Autor:
Lenwood S. Heath, Karthik Raja Velmurugan, Ruth Grene, Doaa Altarawy, Delasa Aghamirzaie, Shuchi Wu
Publikováno v:
F1000Research
Motivation: The increasing availability of chromatin immunoprecipitation sequencing (ChIP-Seq) data enables us to learn more about the action of transcription factors in the regulation of gene expression. Even though in vivo transcriptional regulatio
Autor:
Hongseok Tae, Zalman Vaksman, Karthik Raja Velmurugan, Lauren J. McIver, Harold R. Garner, Natalie C. Fonville
Publikováno v:
Scientific Reports
The human genome is 99% complete. This study contributes to filling the 1% gap by enriching previously unknown repeat regions called microsatellites (MST). We devised a Global MST Enrichment (GME) kit to enrich and nextgen sequence 2 colorectal cell
Publikováno v:
Advances in Bioinformatics, Vol 2015 (2015)
Advances in Bioinformatics
Advances in Bioinformatics
The emerging genome-wide hairpin bisulfite sequencing (hairpin-BS-Seq) technique enables the determination of the methylation pattern for DNA double strands simultaneously. Compared with traditional bisulfite sequencing (BS-Seq) techniques, hairpin-B
Publikováno v:
Cancer Research. 77:553-553
There remains a large discrepancy between the known genetic contributions to cancer and that which can be explained by genomic variants, both inherited and somatic. Recently, understudied repetitive DNA regions called microsatellites have been identi