Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Karthik Nadendla"'
Autor:
Suman Saurabh, Karthik Nadendla, Shubh Sanket Purohit, Ponnurengam Malliappan Sivakumar, Sibel Cetinel
Intrinsically disordered proteins (IDPs) and regions (IDRs) form a large part of the eukaryotic proteome. Contrary to the structure-function paradigm, the disordered proteins perform a myriad of functions in vivo. Consequently, they are involved in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bab27b1b689d826964cec8050f6d295
Autor:
Tuomas P. J. Knowles, Tuuli A. Hakala, Zenon Toprakcioglu, Christopher M. Dobson, Emma V. Yates, Karthik Nadendla, Dijana Matak-Vinkovic, Francisco Corzana, Gonçalo J. L. Bernardes, Pavan K. Challa, Rodrigo Martínez
Publikováno v:
Journal of the American Chemical Society
Funder: Frances and Augustus Newman Foundation
Funder: Emmanuel College, University of Cambridge
Funder: Biotechnology and Biological Sciences Research Council
Funder: Centre for Misfolding Diseases, University of Cambridge
Funder
Funder: Emmanuel College, University of Cambridge
Funder: Biotechnology and Biological Sciences Research Council
Funder: Centre for Misfolding Diseases, University of Cambridge
Funder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c11a8321fa45d94bf1d8012e6e99a46
Publikováno v:
Molecular Pharmaceutics. 16:2922-2928
We have previously described the photoactivated depot (PAD) approach for the light-stimulated release of therapeutic proteins such as insulin. The aim of this method is to release insulin from a shallow dermal depot in response to blood glucose infor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6704d084717c6078fd60d4bf665c91
https://doi.org/10.1021/acs.molpharmaceut.9b00140
https://doi.org/10.1021/acs.molpharmaceut.9b00140
Publikováno v:
Methods in enzymology. 624
In this work we describe methods for synthesizing and incorporating a wide range of photocleavable groups into proteins. These are based on the di-methoxyl nitro phenyl ethyl (DMNPE) group. Using a common ketone starting material, we have modified th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337c9f838186344fab23d906cd2b4e05
https://pubmed.ncbi.nlm.nih.gov/31370926
https://pubmed.ncbi.nlm.nih.gov/31370926
Autor:
Karthik Nadendla, Simon H. Friedman
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0683a2893dd2cc13b827f2a8e99e9fdd
https://doi.org/10.1096/fasebj.2018.32.1_supplement.530.33
https://doi.org/10.1096/fasebj.2018.32.1_supplement.530.33
Autor:
Simon H. Friedman, Karthik Nadendla
Publikováno v:
Journal of the American Chemical Society. 139(49)
We previously have described the photoactivated depot or PAD approach that allows for the light control of therapeutic protein release. This approach relies on the ability to use light to change a protein’s solubility. Traditionally this was accomp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5dc129e9e53a78e5e673e31eebe7202
https://pubmed.ncbi.nlm.nih.gov/29192764
https://pubmed.ncbi.nlm.nih.gov/29192764