Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Karthik Mohanraj"'
Autor:
Maria Sladowska, Michał Turek, Min-Ji Kim, Krzysztof Drabikowski, Ben Hur Marins Mussulini, Karthik Mohanraj, Remigiusz A Serwa, Ulrike Topf, Agnieszka Chacinska
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001302 (2021)
Defects in mitochondrial function activate compensatory responses in the cell. Mitochondrial stress that is caused by unfolded proteins inside the organelle induces a transcriptional response (termed the "mitochondrial unfolded protein response" [UPR
Externí odkaz:
https://doaj.org/article/1e1f62b124cb4c2ba9c4c19570b57648
Autor:
Karthik Mohanraj, Michal Wasilewski, Cristiane Benincá, Dominik Cysewski, Jaroslaw Poznanski, Paulina Sakowska, Zaneta Bugajska, Markus Deckers, Sven Dennerlein, Erika Fernandez‐Vizarra, Peter Rehling, Michal Dadlez, Massimo Zeviani, Agnieszka Chacinska
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 5, Pp 1-21 (2019)
Abstract Nuclear and mitochondrial genome mutations lead to various mitochondrial diseases, many of which affect the mitochondrial respiratory chain. The proteome of the intermembrane space (IMS) of mitochondria consists of several important assembly
Externí odkaz:
https://doaj.org/article/03dc98b418614bc6bc41907e2c528d8b
Autor:
Katarzyna Justyna Chojnacka, Praveenraj Elancheliyan, Ben Hur Marins Mussulini, Karthik Mohanraj, Sylvie Callegari, Aleksandra Gosk, Tomasz Banach, Tomasz Góral, Karolina Szczepanowska, Peter Rehling, Remigiusz Adam Serwa, Agnieszka Chacinska
Publikováno v:
Molecular biology of the cell. 33(4)
Using a combination of techniques (mass spectrometry, BN–PAGE, immunodetection, and mitochondrial in vitro import assays), it is reported that a previously poorly described protein, OCIAD2, localizes to the inner mitochondrial membrane and particip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9782580727545776108364697484305
https://pubmed.ncbi.nlm.nih.gov/35080992
https://pubmed.ncbi.nlm.nih.gov/35080992
Autor:
Agnieszka Chacinska, Praveenraj Elanchelyan, Katarzyna Chojnacka, Karthik Mohanraj, Aleksandra Gosk, Tomasz Goral, Sylvie Callegari, Ben Hur Marins Mussulini, Tomasz Banach, Remigiusz Adam Serwa, Peter Rehling
Assembly of the dimeric complex III (CIII2) in the mitochondrial inner membrane is an intricate process in which many factors are involved. Despite many studies this process is yet to be completely understood. Here we report the identification of hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23b4e8ac0f37d5fe612260ff235ac7e3
https://doi.org/10.1101/2020.12.09.417287
https://doi.org/10.1101/2020.12.09.417287
Publikováno v:
The Biochemical journal. 477(16)
Mitochondria are involved in several vital functions of the eukaryotic cell. The majority of mitochondrial proteins are coded by nuclear DNA. Constant import of proteins from the cytosol is a prerequisite for the efficient functioning of the organell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b192c1f852771e50e7b48f82ffa640ee
https://pubmed.ncbi.nlm.nih.gov/32845275
https://pubmed.ncbi.nlm.nih.gov/32845275
Autor:
Katarzyna Kisielewska, Malgorzata Urbanska, Agnieszka Chacinska, Ewa Liszewska, Lukasz Samluk, Jacek Jaworski, Karthik Mohanraj, Katarzyna Machnicka, Min-Ji Kim
Publikováno v:
Molecular Biology of the Cell
Previous studies demonstrated that cells inhibit protein synthesis as a compensatory mechanism for mitochondrial dysfunction. Protein synthesis can be attenuated by 1) the inhibition of mTOR kinase, which results in a decrease in the phosphorylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d486b33c61de377315142baf8f4123aa
https://pubmed.ncbi.nlm.nih.gov/31116686
https://pubmed.ncbi.nlm.nih.gov/31116686
Autor:
Jarosław Poznański, Markus Deckers, Agnieszka Chacinska, Erika Fernandez-Vizarra, Sven Dennerlein, Michal Dadlez, Michał Wasilewski, Zaneta Bugajska, Cristiane Benincá, Karthik Mohanraj, Paulina Sakowska, Peter Rehling, Dominik Cysewski, Massimo Zeviani
Publikováno v:
EMBO Molecular Medicine
Nuclear and mitochondrial genome mutations lead to various mitochondrial diseases, many of which affect the mitochondrial respiratory chain. The proteome of the intermembrane space (IMS) of mitochondria consists of several important assembly factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc3eead4a6244c6a254c7ac0b112ce1
http://hdl.handle.net/11577/3354168
http://hdl.handle.net/11577/3354168
Autor:
Karthik Mohanraj, Paulina Sakowska, Daniel C. Jans, Stefan Jakobs, Dietmar Riedel, Agnieszka Chacinska
Publikováno v:
Molecular and Cellular Biology
The function of mitochondria depends on the proper organization of mitochondrial membranes. The morphology of the inner membrane is regulated by the recently identified mitochondrial contact site and crista organizing system (MICOS) complex. MICOS mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b154a7c95895bcea78839db4aecd73
http://europepmc.org/articles/PMC4648825
http://europepmc.org/articles/PMC4648825
Publikováno v:
PLoS ONE. Apr2013, Vol. 8 Issue 4, p1-6. 6p.
Autor:
Karthik, Mohanraj, Subhra, Subhadra, Aravindan, Kalyanasundaram, Manikkavasagan, Ilangopathy, Muthusamy, Raman
Publikováno v:
Journal of parasitic diseases : official organ of the Indian Society for Parasitology. 41(1)
Extensive and indiscriminate use of the benzimidazole class of drugs has led to the onset of anthelmintic resistance. In tropical countries like India, Haemonchus contortus is the most pathogenic parasite infecting sheep and goats. The widespread pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::815d5f6e3a07eee07c81119bb29b3887
https://pubmed.ncbi.nlm.nih.gov/28316426
https://pubmed.ncbi.nlm.nih.gov/28316426