Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Karthik Dhatchinamoorthy"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Major histocompatibility class I (MHC I) molecules bind peptides derived from a cell's expressed genes and then transport and display this antigenic information on the cell surface. This allows CD8 T cells to identify pathological cells that are synt
Externí odkaz:
https://doaj.org/article/3f652a5bfbb04887a7bb8d6c894cf43e
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Major histocompatibility class I (MHC I) molecules bind peptides derived from a cell's expressed genes and then transport and display this antigenic information on the cell surface. This allows CD8 T cells to identify pathological cells that are synt
Publikováno v:
Current Genetics. 64:1197-1203
Successful proliferation and function of an organism relies on the equal segregation of its genetic material during cell division. Duplicate sister chromatids need to accurately segregate at mitosis. Precise segregation depends on a multicomplex prot
Autor:
Karthik Dhatchinamoorthy, Geetha S. Hewawasam, Chris Seidel, Mark Mattingly, Jennifer L. Gerton
Publikováno v:
Nucleic Acids Research
Correct localization of the centromeric histone variant CenH3/CENP-A/Cse4 is an important part of faithful chromosome segregation. Mislocalization of CenH3 could affect chromosome segregation, DNA replication and transcription. CENP-A is often overex
Autor:
Jay R. Unruh, Jeffrey J. Lange, Manjunatha Shivaraju, Brian D. Slaughter, Boris Rubinstein, Karthik Dhatchinamoorthy, Jennifer L. Gerton
Publikováno v:
The Journal of Cell Biology
Dhatchinamoorthy et al. use calibrated imaging, FRAP, and photoconversion to study the changes in kinetochore component copy numbers from G1 to anaphase and find that the Dam1 submodule is unchanged during anaphase, whereas MIND and Ndc80 submodules
Autor:
Jeffrey J. Lange, Jay R. Unruh, Brian D. Slaughter, Michaella J. Levy, Jennifer L. Gerton, Karthik Dhatchinamoorthy
Publikováno v:
The Journal of Cell Biology
Dhatchinamoorthy et al. suggest the stoichiometry of outer submodules of the budding yeast kinetochore is strongly influenced by factors at the kinetochore–microtubule interface such as Fin1 and Dam1. Outer kinetochore stoichiometry is remarkably p
Autor:
Macmillan Nongkhlaw, Karthik Dhatchinamoorthy, Mohit Mazumder, Rohini Muthuswami, Samudrala Gourinath, Sneha Sudha Komath, Meghna Gupta, Dominic Thangminlen Haokip
Publikováno v:
FEBS Journal. 282:3841-3859
Mutations and deletions in SMARCAL1, an SWI2/SNF2 protein, cause Schimke immuno-osseous dysplasia (SIOD). SMARCAL1 preferentially binds to DNA molecules possessing double-stranded to single-stranded transition regions and mediates annealing helicase