Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Karthigeyan Nagarajan"'
Autor:
Denise Wootten, Patrick M. Sexton, Laurence J. Miller, Ingrid Mechin, Anil Nair, Andrew Orry, Ruben Abagyan, Karthigeyan Nagarajan, Polo C.-H. Lam, Aditya J. Desai, Celine Valant, Arthur Christopoulos
Publikováno v:
Molecular Pharmacology. 95:245-259
Allosteric modulation of receptors provides mechanistic safety while effectively achieving biologic endpoints otherwise difficult or impossible to obtain by other means. The theoretical case has been made for the development of a positive allosteric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c9bc25645b7738741cf3ef5e518422
https://doi.org/10.1124/mol.118.114082
https://doi.org/10.1124/mol.118.114082
Publikováno v:
Crystal Growth & Design. 1:131-142
Nucleation and crystallization of isotactic polypropylene (iPP) has been simulated using molecular dynamics (MD) with and without nucleating agents. MD simulations were carried out with four iPP chains of 90, 180, 270, and 360 backbone carbons each i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::122fb55a8385292197af5f3b68eac652
https://doi.org/10.1021/cg0055124
https://doi.org/10.1021/cg0055124
Autor:
Ni Ai, Ching Y Wang, Sonia Arora, William J. Welsh, Randy J. Zauhar, Eric Erenrich, Douglas Young, Karthigeyan Nagarajan
Publikováno v:
Chemical research in toxicology. 19(12)
The physiological roles of estrogen in sexual differentiation and development, female and male reproductive processes, and bone health are complex and diverse. Numerous natural and synthetic chemical compounds, commonly known as endocrine disrupting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ac8e8fb14760cebc13268fbc20c7dc
https://pubmed.ncbi.nlm.nih.gov/17173372
https://pubmed.ncbi.nlm.nih.gov/17173372
Publikováno v:
ChemInform. 36
Shape Signatures, a new 3-dimensional molecular comparison method, has been adapted to rank ligands of the serotonin receptors. A set of 825 agonists and 400 antagonists together with approximately 10 000 randomly chosen compounds from the NCI databa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c35b377a7ec5b5160b41c712b68a9ee
https://doi.org/10.1002/chin.200515225
https://doi.org/10.1002/chin.200515225
Publikováno v:
Journal of chemical information and modeling. 45(1)
Shape Signatures, a new 3-dimensional molecular comparison method, has been adapted to rank ligands of the serotonin receptors. A set of 825 agonists and 400 antagonists together with approximately 10,000 randomly chosen compounds from the NCI databa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1c8d30362cea367386a9bd60836da3
https://pubmed.ncbi.nlm.nih.gov/15667128
https://pubmed.ncbi.nlm.nih.gov/15667128