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Autor:
Julia Ritterhoff, Mirko Völkers, Andreas Seitz, Kristin Spaich, Karten Peppel, Sven Pleger, Wolfram Zimmermann, Oliver Friedrich, Rainer Fink, Walter Koch, Hugo Katus, Patrick Most
Publikováno v:
Circulation Research. 115
S100A1 has emerged as a key factor in the control of cardiomyocyte (CM) contractile performance. Improved sarcoplasmic reticulum (SR) function with enhanced Ca2+ resequestration appears critical for its cAMP-independent inotropic effects but raises c