Zobrazeno 1 - 10 of 458 pro vyhledávání: '"Kartberg F"'
1
Akademický článek
Biologically informed machine learning modeling of immune cells to reveal physiological and pathological aging process.
Autor: Zhang, Cangang1,2,3 (AUTHOR), Ren, Tao4,5 (AUTHOR), Zhao, Xiaofan6 (AUTHOR), Su, Yanhong1,2,3 (AUTHOR), Wang, Qianhao1,2,3 (AUTHOR), Zhang, Tianzhe1,2,3 (AUTHOR), He, Boxiao7 (AUTHOR), Chen, Yabing8 (AUTHOR), Wu, Ling-Yun4,5 (AUTHOR), Sun, Lina1,2,3 (AUTHOR) lina.sun@xjtu.edu.cn, Zhang, Baojun1,2,3 (AUTHOR) bj.zhang@mail.xjtu.edu.cn, Xia, Zheng6,9,10 (AUTHOR) xiaz@ohsu.edu
Publikováno v: Immunity & Ageing. 10/24/2024, Vol. 21 Issue 1, p1-21. 21p.
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2
Akademický článek
Deciphering the intracellular forces shaping mitochondrial motion.
Autor: Fernández Casafuz, Agustina Belén1 (AUTHOR) afcasafuz@ic.fcen.uba.ar, Brigante, Azul Marí-a2 (AUTHOR), De Rossi, Marí-a Cecilia3,4 (AUTHOR), Monastra, Alejandro Gabriel4,5 (AUTHOR), Bruno, Luciana1,4 (AUTHOR) luciana.bruno@ic.fcen.uba.ar
Publikováno v: Scientific Reports. 10/13/2024, Vol. 14 Issue 1, p1-12. 12p.
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3
Akademický článek
Integrated serum pharmacochemistry, 16S rDNA sequencing, and metabolomics to reveal the material basis and mechanism of Shouhui Tongbian capsule against diphenoxylate-induced slow transit constipation in rats.
Autor: Yang, Jiaying1,2 (AUTHOR), Xiao, He3 (AUTHOR), Yao, Jingchun3 (AUTHOR), Zhang, Pin4 (AUTHOR), Yi, Bojiao4 (AUTHOR), Fang, Zhengyu1 (AUTHOR), Guo, Na1 (AUTHOR) guona5246@126.com, Guan, Yongxia3 (AUTHOR) 13581069215@163.com, Zhang, Guimin3 (AUTHOR) lunanzhangguiming@yeah.net
Publikováno v: Chinese Medicine. 10/11/2024, Vol. 19 Issue 1, p1-18. 18p.
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4
Akademický článek
Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life.
Autor: Uhlmann RE; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany.; Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany., Rother C; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany.; Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany., Rasmussen J; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany.; Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany., Schelle J; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany., Bergmann C; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Ullrich Gavilanes EM; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany., Fritschi SK; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany., Buehler A; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany., Baumann F; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany., Skodras A; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany., Al-Shaana R; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany., Beschorner N; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany., Ye L; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany., Kaeser SA; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany., Obermüller U; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany., Christensen S; Department of Biotherapeutic Discovery, H. Lundbeck A/S, Copenhagen, Denmark., Kartberg F; Department of Biotherapeutic Discovery, H. Lundbeck A/S, Copenhagen, Denmark., Stavenhagen JB; Department of Biotherapeutic Discovery, H. Lundbeck A/S, Copenhagen, Denmark., Rahfeld JU; Department of Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, Halle, Germany., Cynis H; Department of Drug Design and Target Validation, Fraunhofer Institute for Cell Therapy and Immunology, Halle, Germany., Qian F; Biogen Inc., Cambridge, MA, USA., Weinreb PH; Biogen Inc., Cambridge, MA, USA., Bussiere T; Biogen Inc., Cambridge, MA, USA., Walker LC; Department of Neurology and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA., Staufenbiel M; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Jucker M; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany. mathias.jucker@uni-tuebingen.de.; German Center for Neurodegenerative Diseases, Tübingen, Tübingen, Germany. mathias.jucker@uni-tuebingen.de.
Publikováno v: Nature neuroscience [Nat Neurosci] 2020 Dec; Vol. 23 (12), pp. 1580-1588. Date of Electronic Publication: 2020 Nov 16.
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5
Akademický článek
Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function.
Autor: Sandmark J; Structure, Biophysics and Fragment-Based Lead Generation, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden jenny.sandmark@astrazeneca.com., Tigerström A; Precision Medicine BioPharmaceuticals, Precision Medicine, Oncology R&D, AstraZeneca, Gothenburg, Sweden., Akerud T; Structure, Biophysics and Fragment-Based Lead Generation, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Althage M; Translational Science and Experimental Medicine, Early CVRM Biopharmaceutical R&D, AstraZeneca, Gothenburg, Sweden., Antonsson T; Medicinal Chemistry, Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Blaho S; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Bodin C; Structure, Biophysics and Fragment-Based Lead Generation, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Boström J; Medicinal Chemistry, Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Chen Y; Medicinal Chemistry, Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Dahlén A; Medicinal Chemistry, Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Eriksson PO; Structure, Biophysics and Fragment-Based Lead Generation, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Evertsson E; Medicinal Chemistry, Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Fex T; Medicinal Chemistry, Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Fjellström O; Research and Early Development, Cardiovascular, Renal and Metabolism, Biopharmaceutical R&D, AstraZeneca, Gothenburg, Sweden., Gustafsson D; Bioscience Cardiovascular, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Herslöf M; Medicinal Chemistry, Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Hicks R; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Jarkvist E; Bioscience Cardiovascular, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Johansson C; Structure, Biophysics and Fragment-Based Lead Generation, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Kalies I; Bioscience Cardiovascular, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Karlsson Svalstedt B; Bioscience Cardiovascular, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Kartberg F; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Legnehed A; Bioscience Cardiovascular, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Martinsson S; Bioscience Cardiovascular, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Moberg A; Structure, Biophysics and Fragment-Based Lead Generation, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Ridderström M; Drug Metabolism and Pharmacokinetics, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Rosengren B; Bioscience Cardiovascular, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Sabirsh A; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Thelin A; Bioscience Cardiovascular, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Vinblad J; Bioscience Cardiovascular, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Wellner AU; Medicinal Chemistry, Cardiovascular, Renal and Metabolism, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Xu B; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Östlund-Lindqvist AM; Bioscience Cardiovascular, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Knecht W; Bioscience Cardiovascular, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden Wolfgang.Knecht@biol.lu.se.
Publikováno v: The Journal of biological chemistry [J Biol Chem] 2020 Apr 10; Vol. 295 (15), pp. 5136-5151. Date of Electronic Publication: 2020 Mar 04.
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6
Akademický článek
Tau in neurodegenerative diseases: molecular mechanisms, biomarkers, and therapeutic strategies.
Autor: Zhang, Xingyu1 (AUTHOR), Wang, Jiangyu1 (AUTHOR), Zhang, Zhentao1,2 (AUTHOR) zhentaozhang@whu.edu.cn, Ye, Keqiang3 (AUTHOR) kq.ye@siat.ac.cn
Publikováno v: Translational Neurodegeneration. 8/6/2024, Vol. 13 Issue 1, p1-17. 17p.
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7
Akademický článek
Investigating the Conformational Response of the Sortilin Receptor upon Binding Endogenous Peptide- and Protein Ligands by HDX-MS.
Autor: Trabjerg E; Protein Analysis Group, Department of Pharmacy, University of Copenhagen, 2100 Copenhagen, Denmark; Biotherapeutic Discovery, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark., Abu-Asad N; Protein Analysis Group, Department of Pharmacy, University of Copenhagen, 2100 Copenhagen, Denmark., Wan Z; Protein Analysis Group, Department of Pharmacy, University of Copenhagen, 2100 Copenhagen, Denmark., Kartberg F; Biotherapeutic Discovery, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark., Christensen S; Biotherapeutic Discovery, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark., Rand KD; Protein Analysis Group, Department of Pharmacy, University of Copenhagen, 2100 Copenhagen, Denmark. Electronic address: kasper.rand@sund.ku.dk.
Publikováno v: Structure (London, England : 1993) [Structure] 2019 Jul 02; Vol. 27 (7), pp. 1103-1113.e3. Date of Electronic Publication: 2019 May 16.
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8
Akademický článek
Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes.
Autor: Andersson CR; Department of Neurodegeneration, H. Lundbeck A/S, Copenhagen, Denmark. CRUA@lundbeck.com.; Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark. CRUA@lundbeck.com., Falsig J; Department of Neurodegeneration, H. Lundbeck A/S, Copenhagen, Denmark., Stavenhagen JB; Biology, Therachon, Basel, Switzerland., Christensen S; Biologics, H. Lundbeck A/S, Copenhagen, Denmark., Kartberg F; Biologics, H. Lundbeck A/S, Copenhagen, Denmark., Rosenqvist N; Department of Neurodegeneration, H. Lundbeck A/S, Copenhagen, Denmark., Finsen B; Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Pedersen JT; Department of Neurodegeneration, H. Lundbeck A/S, Copenhagen, Denmark.
Publikováno v: Scientific reports [Sci Rep] 2019 Mar 15; Vol. 9 (1), pp. 4658. Date of Electronic Publication: 2019 Mar 15.
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9
Akademický článek
Highly specific and selective anti-pS396-tau antibody C10.2 targets seeding-competent tau.
Autor: Rosenqvist N; H. Lundbeck A/S, Valby, Denmark., Asuni AA; H. Lundbeck A/S, Valby, Denmark., Andersson CR; H. Lundbeck A/S, Valby, Denmark., Christensen S; H. Lundbeck A/S, Valby, Denmark., Daechsel JA; H. Lundbeck A/S, Valby, Denmark., Egebjerg J; H. Lundbeck A/S, Valby, Denmark., Falsig J; H. Lundbeck A/S, Valby, Denmark., Helboe L; H. Lundbeck A/S, Valby, Denmark., Jul P; H. Lundbeck A/S, Valby, Denmark., Kartberg F; H. Lundbeck A/S, Valby, Denmark., Pedersen LØ; H. Lundbeck A/S, Valby, Denmark., Sigurdsson EM; Department of Neuroscience and Physiology, New York University School of Medicine, New York, NY, USA.; Department of Psychiatry, New York University School of Medicine, New York, NY, USA., Sotty F; H. Lundbeck A/S, Valby, Denmark., Skjødt K; Department of Cancer and Inflammarion Research, University of Southern Denmark, Odense C, Denmark., Stavenhagen JB; Therachon AG, Basel, Switzerland., Volbracht C; H. Lundbeck A/S, Valby, Denmark., Pedersen JT; H. Lundbeck A/S, Valby, Denmark.
Publikováno v: Alzheimer's & dementia (New York, N. Y.) [Alzheimers Dement (N Y)] 2018 Oct 14; Vol. 4, pp. 521-534. Date of Electronic Publication: 2018 Oct 14 (Print Publication: 2018).
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10
Akademický článek
Urban Meteorology, Pollutants, Geomorphology, Fractality, and Anomalous Diffusion.
Autor: Pacheco, Patricio1 (AUTHOR) emera@utem.cl, Mera, Eduardo1 (AUTHOR), Navarro, Gustavo2 (AUTHOR) gustavo.navarro@uss.cl, Parodi, Carolina3 (AUTHOR) cparodi@utem.cl
Publikováno v: Fractal & Fractional. Apr2024, Vol. 8 Issue 4, p204. 32p.
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