Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Karsten R O, Hazlett"'
Autor:
Lauren E. Shoudy, Prachi Namjoshi, Gabriela Giordano, Sudeep Kumar, Jennifer D. Bowling, Carl Gelhaus, Eileen M. Barry, Allan J. Hazlett, Brian A. Hazlett, Kristine L. Cooper, Phillip R. Pittman, Douglas S. Reed, Karsten R. O. Hazlett
Publikováno v:
Pathogens, Vol 10, Iss 12, p 1646 (2021)
Identifying correlates of protection (COPs) for vaccines against lethal human (Hu) pathogens, such as Francisella tularensis (Ft), is problematic, as clinical trials are currently untenable and the relevance of various animal models can be controvers
Externí odkaz:
https://doaj.org/article/19b1e2a7191549959b4507ce19fe0d2f
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Francisella tularensis (Ft) is a biothreat agent for which there is no FDA-approved human vaccine. Currently, there are substantial efforts underway to develop both vaccines and improved tools to assess these vaccines. Ft expresses distinct sets of a
Externí odkaz:
https://doaj.org/article/f7b23b2a99fd4d44bfb40e479694f39b
Autor:
Raju Sunagar, Sudeep Kumar, Prachi Namjoshi, Sarah J Rosa, Karsten R O Hazlett, Edmund J Gosselin
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0207587 (2018)
Francisella tularensis (Ft) is a biothreat agent for which there is no FDA-approved human vaccine. Currently, there are substantial efforts underway to develop both vaccines and the tools to assess these vaccines. Tularemia laboratory research has hi
Externí odkaz:
https://doaj.org/article/e4fdf5fdb3f34f85b959a55d40ccc73f
Autor:
Katherine J O'Malley, Jennifer D Bowling, Elizabeth Stinson, Kelly S Cole, Barbara J Mann, Prachi Namjoshi, Karsten R O Hazlett, Eileen M Barry, Douglas S Reed
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205928 (2018)
Tularemia, also known as rabbit fever, is a severe zoonotic disease in humans caused by the gram-negative bacterium Francisella tularensis (Ft). While there have been a number of attempts to develop a vaccine for Ft, few candidates have advanced beyo
Externí odkaz:
https://doaj.org/article/2fd974cb829c404a8034e7d2e715d828
Autor:
Kristen M. Holland, Sarah J. Rosa, Kolbrun Kristjansdottir, Donald Wolfgeher, Brian J. Franz, Tiffany M. Zarrella, Sudeep Kumar, Raju Sunagar, Anju Singh, Chandra S. Bakshi, Prachi Namjoshi, Eileen M. Barry, Timothy J. Sellati, Stephen J. Kron, Edmund J. Gosselin, Douglas S. Reed, Karsten R. O. Hazlett
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
The gram-negative bacterium Francisella tularensis (Ft) is both a potential biological weapon and a naturally occurring microbe that survives in arthropods, fresh water amoeba, and mammals with distinct phenotypes in various environments. Previously,
Externí odkaz:
https://doaj.org/article/9fad3173896d4d9495261add6d16382a
Publikováno v:
Molecules
Molecules, Vol 26, Iss 1479, p 1479 (2021)
Molecules, Vol 26, Iss 1479, p 1479 (2021)
Bioconjugation has allowed scientists to combine multiple functional elements into one biological or biochemical unit. This assembly can result in the production of constructs that are targeted to a specific site or cell type in order to enhance the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6843b4cb186d308df486e757dcf5ba45
http://europepmc.org/articles/PMC7963163
http://europepmc.org/articles/PMC7963163
Autor:
Anju Singh, Tabassum Rahman, Meenakshi Malik, Anthony J Hickey, Cynthia A Leifer, Karsten R O Hazlett, Timothy J Sellati
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58513 (2013)
Francisella tularensis (Ft) is a highly infectious intracellular pathogen and the causative agent of tularemia. Because Ft can be dispersed via small droplet-aerosols and has a very low infectious dose it is characterized as a category A Select Agent
Externí odkaz:
https://doaj.org/article/dc87ae36505742fd8141291e1802287d
Autor:
Prachi Namjoshi, Timothy J. Sellati, Sarah J. Rosa, Edmund J. Gosselin, Lauren E Shoudy, Donald Steiner, Sudeep Kumar, Kristen M Holland-Tummillo, Karsten R. O. Hazlett, Anju Singh
Publikováno v:
Pathogens
Volume 9
Issue 5
Pathogens, Vol 9, Iss 375, p 375 (2020)
Volume 9
Issue 5
Pathogens, Vol 9, Iss 375, p 375 (2020)
The targeting of immunogens/vaccines to specific immune cells is a promising approach for amplifying immune responses in the absence of exogenous adjuvants. However, the targeting approaches reported thus far require novel, labor-intensive reagents f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862f94e54aa76246cdb9aacd08c90307
Autor:
Tiffany M Zarrella, Anju Singh, Constantine Bitsaktsis, Tabassum Rahman, Bikash Sahay, Paul J Feustel, Edmund J Gosselin, Timothy J Sellati, Karsten R O Hazlett
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22335 (2011)
The gram-negative bacterium Francisella tularensis survives in arthropods, fresh water amoeba, and mammals with both intracellular and extracellular phases and could reasonably be expected to express distinct phenotypes in these environments. The pre
Externí odkaz:
https://doaj.org/article/d26e982887ab4c3e88ea0d1b47b2e207
Autor:
Karsten R. O. Hazlett, Douglas S. Reed, Jennifer D. Bowling, Eileen M. Barry, Katherine J. O’Malley
Inhalation of Francisella tularensis causes pneumonic tularemia in humans, a severe disease with a 30 to 60% mortality rate. The reproducible delivery of aerosolized virulent bacteria in relevant animal models is essential for evaluating medical coun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d175557c39276d834227b92f8b697cdc
https://europepmc.org/articles/PMC6652755/
https://europepmc.org/articles/PMC6652755/
