Výsledky vyhledávání - "Karsten G. Stenzel"

Akademický článek

Treatment response lowers tumor symptom burden in recurrent and/or metastatic head and neck cancer

Autor: Markus Hecht, Dennis Hahn, Philipp Wolber, Matthias G. Hautmann, Dietmar Reichert, Steffi Weniger, Claus Belka, Tobias Bergmann, Thomas Göhler, Manfred Welslau, Christina Große-Thie, Orlando Guntinas-Lichius, Jens von der Grün, Panagiotis Balermpas, Katrin Orlowski, Diethelm Messinger, Karsten G. Stenzel, Rainer Fietkau

Publikováno v: BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)

Abstract Background Head and neck squamous cell cancer (HNSCC) frequently causes severe symptoms that may be reduced, when the tumor is successfully treated. The SOCCER trial studied the association of treatment response with patient reported tumor s

Externí odkaz: https://doaj.org/article/b0e785e23cee4e3ebc4a8def0086024d

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A Prospective Real-World Multi-Center Study to Evaluate Progression-Free and Overall Survival of Radiotherapy with Cetuximab and Platinum-Based Chemotherapy with Cetuximab in Locally Recurrent Head and Neck Cancer

Autor: Katrin Orlowski, Dietmar Reichert, Panagiotis Balermpas, Matthias G. Hautmann, T. Bergmann, Rainer Fietkau, D Hahn, Manfred Welslau, Claus Belka, Karsten G. Stenzel, Jens von der Grün, Steffi Weniger, Markus Hecht, Thomas Göhler, Christina Große-Thie, Orlando Guntinas-Lichius, Diethelm Messinger, Philipp Wolber

Publikováno v: Cancers
Volume 13
Issue 14
Cancers, Vol 13, Iss 3413, p 3413 (2021)

Treatment options of locoregional recurrent head and neck squamous cell cancer (HNSCC) include both local strategies as surgery or re-radiotherapy and systemic therapy. In this prospective, multi-center, non-interventional study, patients were treate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1dc04e83b083102722e15c73a9160c9
https://doi.org/10.3390/cancers13143413

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Impact of prophylactic systemic antibiotics (SA) on outcome of patients (pts) with RAS-wildtype (RAS-wt) metastatic colorectal carcinoma (mCRC) treated with cetuximab-based first-line therapy. Subgroup analysis of the german non-interventional study ERBITAG

Autor: Karsten G. Stenzel, Mark-Oliver Zahn, O. Rubanov, I. Zander, S.W. Sahm, Friedrich Overkamp, C. Maintz, C. Hering-Schubert, T. Goehler, J. Janssen

Publikováno v: Annals of Oncology. 30:v218

Background SA are widely used and recommended to ameliorate skin reactions induced by EGFR inhibition. Randomised studies have shown a positive impact of SA on severity of skin reactions, but the influence on outcome are widely unknown. Recent data s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::683ca8377a881b061afd9aa03ea89fb3
https://doi.org/10.1093/annonc/mdz246.053

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Impact of surgical resection of liver metastases on outcome of patients with KRAS-wildtype exon 2 (KRAS-wt) metastatic colorectal carcinoma (mCRC) treated with a cetuximab-based first-line therapy - Interim analysis of the German non-interventional study ERBITAG

Autor: M. Schwittay, C. Hering-Schubert, Ulf P. Neumann, S.W. Sahm, T. Goehler, M.O. Zahn, Karsten G. Stenzel, Friedrich Overkamp, J. Janssen

Publikováno v: Annals of Oncology. 27:vi162

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c61dc08851f134e32d697f882024d92
https://doi.org/10.1093/annonc/mdw370.39

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Impact of prophylactic treatments of cetuximab-based skin reactions in patients with metastatic colorectal carcinoma (mCRC): Interim analysis of the German noninterventional study ERBITAG

Autor: Jan Janssen, Friedrich Overkamp, Karsten G. Stenzel, Michael Schwittay, Stephan Sahm, Mark-Oliver Zahn, Thomas Goehler, Christiane Hering-Schubert, Alma Katharina Steinbach-Buechert

Publikováno v: Journal of Clinical Oncology. 34:675-675

675 Background: Prophylactic treatments are widely used to ameliorate skin reactions induced by EGFR inhibition. Randomised studies have shown a positive impact of prophylactic antibiotics. Methods: Patients (Pts) with KRAS-wt and later RAS-wt mCRC t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80b0d72f00f943dce4530b32753b2c9a
https://doi.org/10.1200/jco.2016.34.4_suppl.675

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Outcome of patients with KRAS exon 2 wildtype (KRAS-wt) metastatic colorectal carcinoma (mCRC) with cetuximab-based first-line treatment in the noninterventional study ERBITAG and impact of comorbidity and age

Autor: Jan Janssen, Alma Katharina Steinbach-Buechert, Ulf P. Neumann, Karsten G. Stenzel, Friedrich Overkamp, Michael Schwittay, Stephan Sahm, Mark-Oliver Zahn, Christiane Hering-Schubert, Thomas Goehler

Publikováno v: Journal of Clinical Oncology. 34:651-651

651 Background: Cetuximab in combination with irinotecan- or oxaliplatin-based chemotherapy has shown to increase ORR, PFS, OS of KRAS-wt mCRC patients (pts). ERBITAG aimed to evaluate safety and efficacy of cetuximab in combination with various firs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b9792134de167b64dd5088d03ea94b7
https://doi.org/10.1200/jco.2016.34.4_suppl.651

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Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix

Autor: Rainer Klocke, Roque Bort, Teresa Donato, Ramiro Jover, Karsten G. Stenzel, Xavier Ponsoda, José V. Castell, Isabel Guillén, María José Gómez-Lechón, Cristina Rodriguez, Dieter Paul

Publikováno v: J CELL PHYSIOL
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Hepatocytes entrapped in collagen gel and cultured in serum-free conditions survived longer than cells cultured on plastic (5 days vs. 3 weeks), showed fewer signs of early cell senescence (no increase in c-fos oncoprotein expression), and maintained

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ce7bf23252fa64b2386976606d083f
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=4523

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Secondary resection in a general mCRC population with cetuximab-based first-line treatment: Interim analysis of the German noninterventional study ERBITAG

Autor: Ulf P. Neumann, Michael Schwerdtfeger, Gernot Reich, Patrick Stuebs, Friedrich Overkamp, Karsten G. Stenzel, Thomas Goehler

Publikováno v: Journal of Clinical Oncology. 31:e14532-e14532

e14532 Background: Resection of liver and/or lung metastases (LM) are a potentially curative option for patients with mCRC. Cetuximab in combination with irinotecan- or oxaliplatin-based chemotherapy has shown to increase the resection rate of primar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413d77e2f89a0bd79ca351343db3d349
https://doi.org/10.1200/jco.2013.31.15_suppl.e14532

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