Photoredox-Catalyzed Site-Selective Generation of Carbanions from C(sp3)–H Bonds in Amines

Autor: Kathiravan Murugesan, Karsten Donabauer, Rok Narobe, Volker Derdau, Armin Bauer, Burkhard König

Publikováno v: ACS Catalysis. 12:3974-3984

The selective activation of sp3 carbon–hydrogen bonds in the presence of multiple C–H bonds is challenging and remains of supreme importance in chemical research. Late-stage modification of complex molecules via sp3 C–H activation is of high pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f992d7bf3e8ff08cc48882c9fdd2b09
https://doi.org/10.1021/acscatal.2c00662

Photoredox Catalyzed Site-Selective Generation of Carbanions from C(sp3)-H bonds in Amines

Autor: Volker Derdau, Kathiravan Murugesan, Burkhard Koenig, Karsten Donabauer, Rok Narobe, Armin Bauer

The selective activation of sp3 carbon-hydrogen bonds in presence of multiple C¬-H bonds is challenging and remains of supreme importance in chemical research. Herein, we describe the activation of a C(sp3) H bond in α position to an amine via a ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d39cb524f6c6cb0beaecfdddfb29d6e
https://doi.org/10.33774/chemrxiv-2021-f7kt8

Photocatalytic Reductive Radical-Polar Crossover for a Base-Free Corey–Seebach Reaction

Autor: Burkhard König, Karsten Donabauer, Stefano Crespi, Kathiravan Murugesan, Urša Rozman

Publikováno v: Chemistry-A European Journal, 26(57), 12945-12950. Wiley-VCH Verlag GmbH & Co. KGaA
Chemistry – A European Journal
Chemistry (Weinheim an Der Bergstrasse, Germany)

A metal‐free generation of carbanion nucleophiles is of prime importance in organic synthesis. Herein we report a photocatalytic approach to the Corey–Seebach reaction. The presented method operates under mild redox‐neutral and base‐free cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e9b9fe861b905a88ecad91ba2b7967
https://research.rug.nl/en/publications/d2933270-9300-4112-b28e-2c166a3bc596

Photocatalytic Carbanion Generation – Benzylation of Aliphatic Aldehydes to Secondary Alcohols

Autor: Gregory S. Huff, Anna Lucia Berger, Karsten Donabauer, Stefano Crespi, Mitasree Maity, Burkhard König

Publikováno v: Chemical Science

We present a redox-neutral method for the photocatalytic generation of carbanions. Benzylic carboxylates are photooxidized by single electron transfer; immediate CO2 extrusion and reduction of the in situ formed radical yields a carbanion capable of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456bcf2b41dafe69e2bc5187d0d406fe
https://epub.uni-regensburg.de/40102/

Strategies for the Photocatalytic Generation of Carbanion Equivalents for Reductant-Free C–C Bond Formations

Autor: Karsten Donabauer, Burkhard König

Publikováno v: Acc. Chem. Res.
Accounts of Chemical Research

Conspectus The use of photocatalysis in organic chemistry has encountered a surge of novel transformations since the start of the 21st century. The majority of these transformations are driven by the generation and subsequent reaction of radicals, ow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7359cef7fa8f552f6e515f19a5fafe