Zobrazeno 1 - 10
of 284
pro vyhledávání: '"Karsten Buschard"'
Autor:
Camilla H. F. Hansen, Danica Jozipovic, Line F. Zachariassen, Dennis S. Nielsen, Axel K. Hansen, Karsten Buschard
Publikováno v:
Journal of Diabetes, Vol 16, Iss 8, Pp n/a-n/a (2024)
Abstract Background We aimed to investigate whether alpha‐galactosylceramide (α‐GalCer)‐producing Bacteroides fragilis could induce natural killer T (NKT) cells in nonobese diabetic (NOD) mice and reduce their diabetes incidence. Methods Five
Externí odkaz:
https://doaj.org/article/4cec84cbefda40dd8af278745cb6220a
Autor:
Hasim Tekin, Knud Josefsen, Lars Krogvold, Knut Dahl-Jørgensen, Ivan Gerling, Flemming Pociot, Karsten Buschard
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-5 (2022)
Abstract Type 1 diabetes (T1D) incidence is increased after COVID-19 infection in children under 18 years of age. Interferon-α-activated oligoadenylate synthetase and downstream RNAseL activation degrade pathogen RNA, but can also damage host RNA wh
Externí odkaz:
https://doaj.org/article/45cc94444b29412fbbb365b36b1fa85a
Autor:
Camilla Hartmann Friis Hansen, Martin Haupt‐Jorgensen, Karsten Buschard, Bente Pakkenberg, Lukasz Krych, Axel Kornerup Hansen
Publikováno v:
Clinical and Translational Discovery, Vol 3, Iss 2, Pp n/a-n/a (2023)
Abstract Background Early antibiotic treatment changes susceptibility to disease in rodent models for type 1 diabetes, but the impact that gestational antibiotics may have on pancreatic embryogenesis and β cell function later in life is still unknow
Externí odkaz:
https://doaj.org/article/863784c01dfa40cab2ace2c2a46937e8
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291063 (2023)
Brown bears (Ursus arctos) prepare for winter by overeating and increasing adipose stores, before hibernating for up to six months without eating, drinking, and with minimal movement. In spring, the bears exit the den without any damage to organs or
Externí odkaz:
https://doaj.org/article/7dae8d694d4d468e9a24ceefcec986bd
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0289258 (2023)
Type 1 diabetes (T1D) is an autoimmune disease with an unexplained rising incidence for which environmental factors like gluten may play a role. Previously, we showed that a gluten-free (GF) diet provided strictly in utero reduces the autoimmune diab
Externí odkaz:
https://doaj.org/article/6cb5e19fa9f14523bb2474d7ccf21b14
Autor:
Knud Josefsen, Lars Krogvold, Ivan C. Gerling, Flemming Pociot, Knut Dahl-Jørgensen, Karsten Buschard
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundAt diagnosis of Type 1 Diabetes (T1D), 30% of the beta cells are dormant, i.e. alive, but inactive. This could reduce beta cell destruction, as cellular stress contributes to beta cell damage. However, the beta cells, that are still active,
Externí odkaz:
https://doaj.org/article/6fed8a15279949969bea1a6ea5593c12
Autor:
Karsten Buschard
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
In this review after a lifelong research career, my personal opinion on the development of type 1 diabetes (T1D) from its very start to clinical manifestation will be described. T1D is a disease of an increased intestinal permeability and a reduced p
Externí odkaz:
https://doaj.org/article/8fc4d3e6a5274ed08f1abe94afde0f76
Autor:
Valdemar Brimnes Ingemann Johansen, Daisy Færø, Karsten Buschard, Karsten Kristiansen, Flemming Pociot, Pia Kiilerich, Knud Josefsen, Martin Haupt-Jorgensen, Julie Christine Antvorskov
Publikováno v:
Cells, Vol 12, Iss 12, p 1567 (2023)
The incidence of the autoimmune disease type 1 diabetes is increasing, likely caused by environmental factors. A gluten-free diet has previously been shown to ameliorate autoimmune diabetes in non-obese diabetic (NOD) mice and humans. Although the ex
Externí odkaz:
https://doaj.org/article/b2c42a13b2a945fd8645ea5dbb6b5f17
Autor:
Pernille Kihl, Lukasz Krych, Ling Deng, Lars H. Hansen, Karsten Buschard, Søren Skov, Dennis S. Nielsen, Axel Kornerup Hansen
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
The purpose of this study was to compare the effect of a gluten-free diet and/or antibiotics on tetanus vaccine induced immunoglobulin G titers and immune cell levels in BALB/c mice. The gluten-free diet was associated with a reduced anti-tetanus IgG
Externí odkaz:
https://doaj.org/article/a320864adfd74147ae7760dab8c0f169
Autor:
Karsten Buschard, Julie C Antvorskov
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 12, p 331 (2022)
Particular molecules play pivotal roles in the pathogenesis of many autoimmune diseases. We suggest that the C24:0 sulfatide isoform may influence the development of type 1 diabetes (T1D). C24:0 sulfatide is a sphingolipid with a long carbon-atom cha
Externí odkaz:
https://doaj.org/article/72cd51afdbb54c3f82a621b642575787