Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Karsten, Hueffer"'
Autor:
Karsten Hueffer
Publikováno v:
International Journal of Circumpolar Health, Vol 83, Iss 1 (2024)
ABSTRACTRabies is often described as the quintessential One Health problem, linking especially animal health to human health. I examined how rabies is managed in the circumpolar North through semi-structured interviews of key informants in three case
Externí odkaz:
https://doaj.org/article/a84f4f48249e43cfb10c43f773564d0b
The human alpha7 nicotinic acetylcholine receptor is a host target for the rabies virus glycoprotein
Autor:
Brittany C. V. O’Brien, Shelly Thao, Lahra Weber, Helen L. Danielson, Agatha D. Boldt, Karsten Hueffer, Maegan M. Weltzin
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
The rabies virus enters the nervous system by interacting with several molecular targets on host cells to modify behavior and trigger receptor-mediated endocytosis of the virion by poorly understood mechanisms. The rabies virus glycoprotein (RVG) int
Externí odkaz:
https://doaj.org/article/257f8c694878437c8613327949462968
Publikováno v:
Heliyon, Vol 8, Iss 9, Pp e10434- (2022)
Rabies causes approximately 60,000 casualties annually and has a case fatality rate approaching 100% once clinical signs occur. The glycoprotein on the surface of the virion is important for the host immune response and facilitates interaction of the
Externí odkaz:
https://doaj.org/article/b65610cb69c3418691d4c1f329dde46b
Autor:
Robert A Hiatt, Yazmin P Carrasco, Alan L Paciorek, Lauren Kaplan, Marc B Cox, Carlos J Crespo, Andrew Feig, Karsten Hueffer, Harris McFerrin, Keith Norris, Elizabeth Roberts-Kirchhoff, Carrie L Saetermoe, Gillian Beth Silver, Katherine Snyder, Arturo R Zavala, Audrey G Parangan-Smith, Diversity Program Consortium
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274100 (2022)
BackgroundThe lack of race/ethnic and gender diversity in grants funded by the National Institutes of Health (NIH) is a persistent challenge related to career advancement and the quality and relevance of health research. We describe pilot programs at
Externí odkaz:
https://doaj.org/article/da39c65205594ab69a83253e3b4423dd
Autor:
Lucy O. Keatts, Martin Robards, Sarah H. Olson, Karsten Hueffer, Stephen J. Insley, Damien O. Joly, Susan Kutz, David S. Lee, Cheryl-Lesley B. Chetkiewicz, Stéphane Lair, Nicholas D. Preston, Mathieu Pruvot, Justina C. Ray, Donald Reid, Jonathan M. Sleeman, Raphaela Stimmelmayr, Craig Stephen, Chris Walzer
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
The COVID-19 pandemic has re-focused attention on mechanisms that lead to zoonotic disease spillover and spread. Commercial wildlife trade, and associated markets, are recognized mechanisms for zoonotic disease emergence, resulting in a growing globa
Externí odkaz:
https://doaj.org/article/01dfaed3d0264891a345458107f4b998
Autor:
Tristan M Baecklund, Jaycee Morrison, Michael E Donaldson, Karsten Hueffer, Christopher J Kyle
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249176 (2021)
Populations are exposed to different types and strains of pathogens across heterogeneous landscapes, where local interactions between host and pathogen may present reciprocal selective forces leading to correlated patterns of spatial genetic structur
Externí odkaz:
https://doaj.org/article/f5b6242bc63843fea76f9394e33b6b51
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
Patterns of local adaptation can emerge in response to the selective pressures diseases exert on host populations as reflected in increased frequencies of respective, advantageous genotypes. Elucidating patterns of local adaptation enhance our unders
Externí odkaz:
https://doaj.org/article/bf1ece8c8ae94a428096a82e10873416
Autor:
Michael E. Donaldson, Yessica Rico, Karsten Hueffer, Halie M. Rando, Anna V. Kukekova, Christopher J. Kyle
Publikováno v:
Ecology and Evolution, Vol 8, Iss 1, Pp 572-583 (2018)
Abstract Pathogens are recognized as major drivers of local adaptation in wildlife systems. By determining which gene variants are favored in local interactions among populations with and without disease, spatially explicit adaptive responses to path
Externí odkaz:
https://doaj.org/article/50ae61711e184f97968b3a2f46efb09a
Autor:
Barbara E. Taylor, Arleigh J. Reynolds, Kathy E. Etz, Nicole M. G. MacCalla, Paul A. Cotter, Tiffany L. DeRuyter, Karsten Hueffer
Publikováno v:
BMC Proceedings, Vol 11, Iss S12, Pp 79-89 (2017)
Abstract Background and purpose Most postsecondary institutions in the state of Alaska (USA) have a broad mission to serve diverse students, many of whom come from schools in rural villages that are accessible only by plane, boat, or snowmobile. The
Externí odkaz:
https://doaj.org/article/2e7535839a1c4f0092f5c0b4b917e059
Publikováno v:
International Journal of Circumpolar Health, Vol 78, Iss 1 (2019)
The North faces significant health disparities, especially among its many Indigenous peoples. In this article we discuss historical, environmental, and cultural variables that contribute to these disparities and propose a One Health approach to addre
Externí odkaz:
https://doaj.org/article/144378e9eeba4dfcabd53cb7288cead2