Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Karrie D. Dudek"'
Autor:
Anna B Osipovich, Karrie D Dudek, Linh T Trinh, Lily H Kim, Shristi Shrestha, Jean-Philippe Cartailler, Mark A Magnuson
Publikováno v:
PLoS Genetics, Vol 19, Iss 5, p e1010729 (2023)
Repressive KRAB domain-containing zinc-finger proteins (KRAB-ZFPs) are abundant in mammalian genomes and contribute both to the silencing of transposable elements (TEs) and to the regulation of developmental stage- and cell type-specific gene express
Externí odkaz:
https://doaj.org/article/958a757243fb446dbbf604462b38535d
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 11 (2021)
Abstract Insm1Neurod1Pax6Insm1Neurod1Pax6Insm1Neurod1Pax6Syt14Snap25Syt14Insm1Pax6Snap25Insm1Neurod1Pax6
Externí odkaz:
https://doaj.org/article/97e3448da97c4d6cbd1e0a4a3fc6f1fc
Autor:
Hui-Young Lee, Hye Rim Jang, Hui Li, Varman T. Samuel, Karrie D. Dudek, Anna B. Osipovich, Mark A. Magnuson, Jeffrey Sklar, Gerald I. Shulman
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Single-nucleotide polymorphisms in the human juxtaposed with another zinc finger protein 1 ( JAZF1 ) gene have repeatedly been associated with both type 2 diabetes (T2D) and height in multiple genome-wide association studies (GWAS); however, the mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0b0323aa8eeb70470f099b2a8b41981
https://doi.org/10.1073/pnas.2213628119
https://doi.org/10.1073/pnas.2213628119
Autor:
Hui-Young, Lee, Hye Rim, Jang, Hui, Li, Varman T, Samuel, Karrie D, Dudek, Anna B, Osipovich, Mark A, Magnuson, Jeffrey, Sklar, Gerald I, Shulman
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(49)
Single-nucleotide polymorphisms in the human juxtaposed with another zinc finger protein 1 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dbb2957cbba7748d0c92caf4cb40667b
https://pubmed.ncbi.nlm.nih.gov/36442127
https://pubmed.ncbi.nlm.nih.gov/36442127
Autor:
Karrie D. Dudek, Anna B. Osipovich, Jennifer S. Stancill, Mark A. Magnuson, Jean-Philippe Cartailler
Publikováno v:
Diabetes
A sustained increase in intracellular Ca2+ concentration (referred to hereafter as excitotoxicity), brought on by chronic metabolic stress, may contribute to pancreatic β-cell failure. To determine the additive effects of excitotoxicity and overnutr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350676f401729eeccdbcc2eb7fc97d5d
https://doi.org/10.2337/db19-1145
https://doi.org/10.2337/db19-1145
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 11, Iss 11 (2021)
G3: Genes, Genomes, Genetics, Vol 11, Iss 11 (2021)
Insm1, Neurod1, and Pax6 are essential for the formation and function of pancreatic endocrine cells. Here, we report comparative immunohistochemical, transcriptomic, functional enrichment, and RNA splicing analyses of these genes using gene knock-out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf947746065354183e00bf5ad7a1447
https://pubmed.ncbi.nlm.nih.gov/34534285
https://pubmed.ncbi.nlm.nih.gov/34534285
Autor:
Karrie D. Dudek, Christian J. Stoeckert, Jean-Philippe Cartailler, Leah Potter Case, Hannah W. Clayton, Anna B. Osipovich, Guoqiang Gu, Emily Greenfest-Allen, Eun-Young Choi, Mark A. Magnuson, Austin Chapman, Elisabetta Manduchi
Publikováno v:
Development. 148
To gain a deeper understanding of pancreatic β-cell development, we used iterative weighted gene correlation network analysis to calculate a gene co-expression network (GCN) from 11 temporally and genetically defined murine cell populations. The GCN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf9b6410dfdc42ba38a9ce4c30fbced2
https://doi.org/10.1242/dev.196964
https://doi.org/10.1242/dev.196964
Autor:
Anna B, Osipovich, Karrie D, Dudek, Emily, Greenfest-Allen, Jean-Philippe, Cartailler, Elisabetta, Manduchi, Leah, Potter Case, Eunyoung, Choi, Austin G, Chapman, Hannah W, Clayton, Guoqiang, Gu, Christian J, Stoeckert, Mark A, Magnuson
Publikováno v:
Development
To gain a deeper understanding of pancreatic β-cell development, we used iterative weighted gene correlation network analysis to calculate a gene co-expression network (GCN) from 11 temporally and genetically defined murine cell populations. The GCN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41e4e29a37cfa242fa371aaf14974e64
https://pubmed.ncbi.nlm.nih.gov/33653874
https://pubmed.ncbi.nlm.nih.gov/33653874
Autor:
Vittorio Maglione, M. Diana Neely, Timothy Halbesma, Alba Di Pardo, Preethi Umashanker, Hunter K. Holt, Nicole M. Fisher, Terry Jo Bichell, Gunnar F. Kwakye, Emma M. Bradley, Miles R. Bryan, Roger J. Colbran, Alexander P. Osmand, Kyle J. Horning, K. Grace Tipps, Michael Aschner, Karrie D. Dudek, Michael A. Uhouse, Andrew D. Stubbs, Aaron B. Bowman, Andrew M. Tidball, Michal Wegrzynowicz
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1863(6)
Huntington's disease (HD) is caused by a mutation in the huntingtin gene (HTT), resulting in profound striatal neurodegeneration through an unknown mechanism. Perturbations in the urea cycle have been reported in HD models and in HD patient blood and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c17f923d70c8682f8081e058ff89587e
https://pubmed.ncbi.nlm.nih.gov/28213125
https://pubmed.ncbi.nlm.nih.gov/28213125