The U UGA C sequence provides a favorable context to ELX-02 induced CFTR readthrough

Autor: Pranke, Iwona M., Varilh, Jessica, Hatton, Aurélie, Faucon, Caroline, Girodon, Emmanuelle, Dreano, Elise, Chevalier, Benoit, Karri, Sabrina, Reix, Philippe, Durieu, Isabelle, Bidou, Laure, Namy, Olivier, Taulan, Magali, Hinzpeter, Alexandre, Sermet-Gaudelus, Isabelle

Publikováno v: In Journal of Cystic Fibrosis May 2023 22(3):560-563

TLN468 changes the pattern of tRNA used to read through premature termination codons in CFTR.

Autor: Karri S; CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, Gif-sur-Yvette, 91198, France., Cornu D; CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, Gif-sur-Yvette, 91198, France., Serot C; CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, Gif-sur-Yvette, 91198, France., Biri L; CNRS, INSERM, Institut Necker Enfants Malades-INEM, Université Paris Cité, Paris, F-75015, France., Hatton A; CNRS, INSERM, Institut Necker Enfants Malades-INEM, Université Paris Cité, Paris, F-75015, France., Dréanot E; CNRS, INSERM, Institut Necker Enfants Malades-INEM, Université Paris Cité, Paris, F-75015, France., Rullaud C; CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, Gif-sur-Yvette, 91198, France., Pranke I; CNRS, INSERM, Institut Necker Enfants Malades-INEM, Université Paris Cité, Paris, F-75015, France., Sermet-Gaudelus I; CNRS, INSERM, Institut Necker Enfants Malades-INEM, Université Paris Cité, Paris, F-75015, France., Hinzpeter A; CNRS, INSERM, Institut Necker Enfants Malades-INEM, Université Paris Cité, Paris, F-75015, France., Bidou L; CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, Gif-sur-Yvette, 91198, France; Sorbonne Université, 4 Place Jussieu, Paris, 75005, France., Namy O; CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, Gif-sur-Yvette, 91198, France. Electronic address: olivier.namy@i2bc.paris-saclay.fr.

Publikováno v: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2024 Aug 03. Date of Electronic Publication: 2024 Aug 03.

Factors influencing readthrough therapy for frequent cystic fibrosis premature termination codons.

Autor: Pranke I; INSERM, U1151, Institut Necker Enfants Malades, INEM, Paris, France.; Université Paris Descartes, Paris, France.; Both authors contributed equally., Bidou L; Sorbonne Universités, Université Pierre et Marie Curie, UPMC, Paris, France.; Institute for Integrative Biology of the Cell, I2BC, CEA, CNRS, Université Paris Sud, Université Paris-Saclay, Gif-sur-Yvette, France.; Both authors contributed equally., Martin N; INSERM, U955, Institut de Recherche Henri Mondor, Créteil, France., Blanchet S; Institute for Integrative Biology of the Cell, I2BC, CEA, CNRS, Université Paris Sud, Université Paris-Saclay, Gif-sur-Yvette, France., Hatton A; INSERM, U1151, Institut Necker Enfants Malades, INEM, Paris, France.; Université Paris Descartes, Paris, France., Karri S; Institute for Integrative Biology of the Cell, I2BC, CEA, CNRS, Université Paris Sud, Université Paris-Saclay, Gif-sur-Yvette, France., Cornu D; Institute for Integrative Biology of the Cell, I2BC, CEA, CNRS, Université Paris Sud, Université Paris-Saclay, Gif-sur-Yvette, France., Costes B; INSERM, U955, Institut de Recherche Henri Mondor, Créteil, France.; Université Paris-Est, Créteil, France., Chevalier B; INSERM, U1151, Institut Necker Enfants Malades, INEM, Paris, France.; Université Paris Descartes, Paris, France., Tondelier D; INSERM, U1151, Institut Necker Enfants Malades, INEM, Paris, France.; Université Paris Descartes, Paris, France., Girodon E; INSERM, U1151, Institut Necker Enfants Malades, INEM, Paris, France.; Laboratoire de Génétique et Biologie Moléculaires, HUPC Hôpital Cochin, AP-HP, Paris, France., Coupet M; Institute for Integrative Biology of the Cell, I2BC, CEA, CNRS, Université Paris Sud, Université Paris-Saclay, Gif-sur-Yvette, France., Edelman A; INSERM, U1151, Institut Necker Enfants Malades, INEM, Paris, France.; Université Paris Descartes, Paris, France., Fanen P; INSERM, U955, Institut de Recherche Henri Mondor, Créteil, France.; Université Paris-Est, Créteil, France.; Dept of Genetics, GH Henri Mondor, AP-HP, Créteil, France., Namy O; Institute for Integrative Biology of the Cell, I2BC, CEA, CNRS, Université Paris Sud, Université Paris-Saclay, Gif-sur-Yvette, France., Sermet-Gaudelus I; INSERM, U1151, Institut Necker Enfants Malades, INEM, Paris, France.; Université Paris Descartes, Paris, France., Hinzpeter A; INSERM, U1151, Institut Necker Enfants Malades, INEM, Paris, France.; Université Paris Descartes, Paris, France.

Publikováno v: ERJ open research [ERJ Open Res] 2018 Feb 23; Vol. 4 (1). Date of Electronic Publication: 2018 Feb 23 (Print Publication: 2018).