Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Karren M Plain"'
Autor:
Kathryn Wright, Kumudika de Silva, Karren M Plain, Auriol C Purdie, Tamika A Blair, Iain G Duggin, Warwick J Britton, Stefan H Oehlers
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009186 (2021)
Pathogenic mycobacteria actively dysregulate protective host immune signalling pathways during infection to drive the formation of permissive granuloma microenvironments. Dynamic regulation of host microRNA (miRNA) expression is a conserved feature o
Externí odkaz:
https://doaj.org/article/ab2479ec6bef4a43a7ab57ae13d447fa
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225524 (2019)
Bovine Johne's disease (JD) is a chronic debilitating disease affecting cattle breeds worldwide. Pooled faecal samples are routinely tested by culture to detect Mycobacterium avium subsp. paratuberculosis (Mptb) infection. More recently, a direct hig
Externí odkaz:
https://doaj.org/article/b49bc36c75774c038e4d6ae505a93a53
Autor:
Shyamala Thirunavukkarasu, Karren M Plain, Auriol C Purdie, Richard J Whittington, Kumudika de Silva
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176400 (2017)
According to most models of mycobacterial infection, inhibition of the pro-inflammatory macrophage immune responses contributes to the persistence of bacteria. Mycobacterium avium subsp. paratuberculosis (MAP) is a highly successful pathogen in cattl
Externí odkaz:
https://doaj.org/article/94925606baab41fdb1d1d3fd6c0a2d16
Publikováno v:
PLoS ONE, Vol 19, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/16c27d185ac14b68b5d47a7b1a62c6c4
Autor:
Hannah B. Pooley, Guneet Panag, Karren M. Plain, Kumudika de Silva, Douglas J. Begg, Richard J. Whittington, Auriol C. Purdie
Publikováno v:
Vaccine. 41:274-283
The cell mediated immune response and ability of immune cells to migrate to the site of infection are both key aspects of protection against many pathogens. Mycobacterium avium subsp. paratuberculosis (MAP) is an intracellular pathogen and the causat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a772fe4d908efdf3e0bc483f9ed2b47
https://doi.org/10.1016/j.vaccine.2022.11.018
https://doi.org/10.1016/j.vaccine.2022.11.018
Publikováno v:
Pathogenesis of Bacterial Infections in Animals. :736-756
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9bb8ab1462980f24d7142dd7fc7f851
https://doi.org/10.1002/9781119754862.ch34
https://doi.org/10.1002/9781119754862.ch34
Autor:
Auriol C. Purdie, Karren M. Plain, Hannah Pooley, Douglas J. Begg, Kumudika de Silva, Richard J. Whittington
Publikováno v:
Frontiers in Veterinary Science. 9
A critical hindrance in the development of effective vaccine strategies to combat infectious disease is lack of knowledge about correlates of protection and of the host responses necessary for successful adaptive immunity. Often vaccine formulations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a69a60ca78feaba1236df594804f023c
https://doi.org/10.3389/fvets.2022.1004237
https://doi.org/10.3389/fvets.2022.1004237
Publikováno v:
Scientific Reports. 12
Pathogenic mycobacteria including Mycobacterium avium subsp. paratuberculosis (MAP), the causative agent of Johne’s disease, manipulate host macrophages to persist and cause disease. In mycobacterial infection, highly plastic macrophages, shift bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf03387d767aab27b7a1aff32aeaec0
https://doi.org/10.1038/s41598-022-13503-8
https://doi.org/10.1038/s41598-022-13503-8
Publikováno v:
Frontiers in Microbiology. 13
Mycobacterium avium is separated into four subspecies: M. avium subspecies avium (MAA), M. avium subspecies silvaticum (MAS), M. avium subspecies hominissuis (MAH), and M. avium subspecies paratuberculosis (MAP). Understanding the mechanisms of host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d625680d25b0d647af01854e9bd715da
https://doi.org/10.3389/fmicb.2022.892333
https://doi.org/10.3389/fmicb.2022.892333
Publikováno v:
Frontiers in microbiology. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48234fbf782c280c35aa2626811bcf57
https://pubmed.ncbi.nlm.nih.gov/35602010
https://pubmed.ncbi.nlm.nih.gov/35602010