Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing.

Autor: Tetzlaff SK; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Functional Neuroanatomy, Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany., Reyhan E; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Layer N; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Bengtson CP; Department of Neurobiology, Interdisciplinary Centre for Neurosciences (IZN), Heidelberg University, Heidelberg, Germany., Heuer A; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Schroers J; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany; Division of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Faymonville AJ; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Langeroudi AP; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Drewa N; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Keifert E; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Wagner J; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany; Department of Functional Neuroanatomy, Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany., Soyka SJ; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany; Department of Functional Neuroanatomy, Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany., Schubert MC; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany; Department of Functional Neuroanatomy, Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany., Sivapalan N; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Pramatarov RL; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany; Department of Functional Neuroanatomy, Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany., Buchert V; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Wageringel T; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Grabis E; Translational Neurosurgery, Friedrich-Alexander University Erlangen Nuremberg, Erlangen, Germany; Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg, Germany., Wißmann N; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany; Department of Functional Neuroanatomy, Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany., Alhalabi OT; Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany., Botz M; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany; Department of Functional Neuroanatomy, Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany., Bojcevski J; Clinical Cooperation Unit Translational Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Campos J; Chica and Heinz Schaller Foundation, Institute of Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany., Boztepe B; Neuroradiology Department, University Hospital Heidelberg, Heidelberg, Germany; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Scheck JG; Clinical Cooperation Unit Translational Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Neuroradiology Department, University Hospital Heidelberg, Heidelberg, Germany., Conic SH; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany., Puschhof MC; Faculty of Medicine, Heidelberg University, and Institute for Computational Biomedicine, Heidelberg University Hospital, Heidelberg, Germany., Villa G; Translational Neurosurgery, Friedrich-Alexander University Erlangen Nuremberg, Erlangen, Germany., Drexler R; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA., Zghaibeh Y; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Hausmann F; Center for Biomedical AI, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Institute of Medical Systems Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Hänzelmann S; Center for Biomedical AI, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Institute of Medical Systems Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Karreman MA; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Kurz FT; Division of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Division of Neuroradiology, University Hospital Geneva, Geneva, Switzerland., Schröter M; ETH Zurich, Department of Biosystems Science and Engineering, Basel, Switzerland., Thier M; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany., Suwala AK; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany; Clinical Cooperation Unit Neuropathology (B300), German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Forsberg-Nilsson K; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 75185 Uppsala, Sweden., Acuna C; Chica and Heinz Schaller Foundation, Institute of Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany., Saez-Rodriguez J; Faculty of Medicine, Heidelberg University, and Institute for Computational Biomedicine, Heidelberg University Hospital, Heidelberg, Germany., Abdollahi A; Clinical Cooperation Unit Translational Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Sahm F; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany; Clinical Cooperation Unit Neuropathology (B300), German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Breckwoldt MO; Neuroradiology Department, University Hospital Heidelberg, Heidelberg, Germany; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Suchorska B; Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany., Ricklefs FL; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Heiland DH; Translational Neurosurgery, Friedrich-Alexander University Erlangen Nuremberg, Erlangen, Germany; Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg, Germany; Department of Neurosurgery, University Hospital Erlangen, Friedrich-Alexander University Erlangen Nuremberg, Erlangen, Germany; Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA; German Cancer Consortium (DKTK), partner site Freiburg, Freiburg, Germany., Venkataramani V; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Functional Neuroanatomy, Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany. Electronic address: varun.venkataramani@med.uni-heidelberg.de.

Publikováno v: Cell [Cell] 2024 Dec 03. Date of Electronic Publication: 2024 Dec 03.

Disturbance in cerebral blood microcirculation and hypoxic-ischemic microenvironment are associated with the development of brain metastasis.

Autor: Roesler J; Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany., Spitzer D; Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany., Jia X; Tianjin Neurosurgical Institute, Tianjin Huanhu Hospital, Tianjin, China.; Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Tianjin Huanhu Hospital, Tianjin, China.; Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany.; Neurosurgery Department, Tianjin Huanhu Hospital, Tianjin, China., Aasen SN; Department of Oncology and Medical Physics, Haukeland University Hospital, Bergen, Norway.; Department of Biomedicine, Kristian Gerhard Jebsen Brain Tumour Research Centre, University of Bergen, Bergen, Norway., Sommer K; Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany., Roller B; Goethe University, University Hospital, Dr. Senckenberg Institute for Neurooncology, Frankfurt, Germany.; Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany., Olshausen N; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Hebach NR; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Albinger N; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Department of Pediatrics, Experimental Immunology and Cell Therapy, Goethe University, University Hospital, Frankfurt, Germany., Ullrich E; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Department of Pediatrics, Experimental Immunology and Cell Therapy, Goethe University, University Hospital, Frankfurt, Germany., Zhu L; Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany., Wang F; Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany., Macas J; Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany., Forster MT; Department of Neurosurgery, Goethe University, University Hospital, Frankfurt, Germany., Steinbach JP; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK) Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Goethe University, University Hospital, Dr. Senckenberg Institute for Neurooncology, Frankfurt, Germany., Sevenich L; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Frankfurt, Germany.; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK) Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany., Devraj K; Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany.; Department of Biological Sciences, Birla Institute of Technology and Science, Pilani, Hyderabad, India., Thorsen F; Department of Biomedicine, Molecular Imaging Center, University of Bergen, Bergen, Norway.; Department of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan, China.; Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway., Karreman MA; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Plate KH; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK) Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany., Reiss Y; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK) Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany., Harter PN; Center for Neuropathology and Prion Research, Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK) Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany.

Publikováno v: Neuro-oncology [Neuro Oncol] 2024 Nov 04; Vol. 26 (11), pp. 2084-2099.

Active Remodeling of Capillary Endothelium via Cancer Cell-Derived MMP9 Promotes Metastatic Brain Colonization.

Autor: Karreman MA; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany., Bauer AT; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Solecki G; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Business Unit Service and Customer Care, Carl Zeiss Microscopy GmbH, Jena, Germany., Berghoff AS; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Medicine I, Division of Oncology, Medical University of Vienna, Comprehensive Cancer Center Vienna, Vienna, Austria., Mayer CD; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Frey K; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Hebach N; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Feinauer MJ; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Schieber NL; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.; Centre for Microscopy and Microanalyses, The University of Queensland, Brisbane, Australia., Tehranian C; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Mercier L; National Institute of Health and Medical Research (INSERM) UMR_S1109, Tumor Biomechanics, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France., Singhal M; European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Division of Vascular Oncology and Metastasis, German Cancer Research Center Heidelberg (DKFZ-ZMBH Alliance), Heidelberg, Germany., Venkataramani V; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Functional Neuroanatomy, Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany., Schubert MC; Department of Functional Neuroanatomy, Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany., Hinze D; LAMPseq Diagnostics GmbH, Bonn, Germany.; Institute of Experimental Oncology, University Hospital Bonn, University of Bonn, Bonn, Germany., Hölzel M; Institute of Experimental Oncology, University Hospital Bonn, University of Bonn, Bonn, Germany., Helfrich I; Skin Cancer Unit of the Dermatology Department, Medical Faculty, West German Cancer Center, University Duisburg-Essen, Essen, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Dermatology and Allergology, Medical Faculty of the Ludwig Maximilian University of Munich, Munich, Germany., Schadendorf D; Skin Cancer Unit of the Dermatology Department, Medical Faculty, West German Cancer Center, University Duisburg-Essen, Essen, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany., Schneider SW; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Westphal D; Department of Dermatology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Augustin HG; European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Division of Vascular Oncology and Metastasis, German Cancer Research Center Heidelberg (DKFZ-ZMBH Alliance), Heidelberg, Germany., Goetz JG; National Institute of Health and Medical Research (INSERM) UMR_S1109, Tumor Biomechanics, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France., Schwab Y; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.; Electron Microscopy Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany., Wick W; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Winkler F; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

Publikováno v: Cancer research [Cancer Res] 2023 Apr 14; Vol. 83 (8), pp. 1299-1314.

The PI3K/Akt/mTOR pathway as a preventive target in melanoma brain metastasis.

Autor: Tehranian C; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Fankhauser L; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Harter PN; Edinger Institute, Institute of Neurology, University of Frankfurt am Main, Frankfurt am Main, Germany.; German Cancer Research Center DKFZ Heidelberg, Germany and German Cancer Consortium DKTK partner site, Frankfurt/Mainz Germany.; Frankfurt Cancer Institute (FCI), Frankfurt am Main, Germany., Ratcliffe CDH; Tumour Cell Biology Laboratory, The Francis Crick Institute, London, UK., Zeiner PS; Edinger Institute, Institute of Neurology, University of Frankfurt am Main, Frankfurt am Main, Germany.; Senckenberg Institute of Neurooncology, University of Frankfurt am Main, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt am Main, Germany., Messmer JM; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Hoffmann DC; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Frey K; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Westphal D; Department of Dermatology, Medical Faculty and University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany., Ronellenfitsch MW; Senckenberg Institute of Neurooncology, University of Frankfurt am Main, Frankfurt am Main, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt am Main, Germany., Sahai E; Tumour Cell Biology Laboratory, The Francis Crick Institute, London, UK., Wick W; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Karreman MA; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Winkler F; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.

Publikováno v: Neuro-oncology [Neuro Oncol] 2022 Feb 01; Vol. 24 (2), pp. 213-225.

Local blood coagulation drives cancer cell arrest and brain metastasis in a mouse model.

Autor: Feinauer MJ; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany., Schneider SW; Department of Dermatology and Venereology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Berghoff AS; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.; Division of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria., Robador JR; Department of Dermatology and Venereology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Tehranian C; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany., Karreman MA; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany., Venkataramani V; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.; Department of Functional Neuroanatomy, Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany., Solecki G; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.; Business Unit Service and Customer Care, Carl Zeiss Microscopy GmbH, Jena, Germany., Grosch JK; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany., Gunkel K; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany., Kovalchuk B; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany., Mayer FT; Department of Dermatology and Venereology, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Fischer M; Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany., Breckwoldt MO; Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany., Brune M; Department of Endocrinology and Clinical Chemistry, Medical University Hospital, Heidelberg, Germany; and., Schwab Y; Cell Biology and Biophysics Unit, and Electron Microscopy Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany., Wick W; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany., Bauer AT; Department of Dermatology and Venereology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Winkler F; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.

Publikováno v: Blood [Blood] 2021 Mar 04; Vol. 137 (9), pp. 1219-1232.