Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Karpicheva OE"'
1
Akademický článek
Myosin's powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin.
Autor: Rynkiewicz MJ; Department of Pharmacology, Physiology and Biophysics, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA., Childers MC; Department of Bioengineering, University of Washington, Seattle, WA, USA., Karpicheva OE; Department of Pharmacology, Physiology and Biophysics, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA., Regnier M; Department of Bioengineering, University of Washington, Seattle, WA, USA., Geeves MA; School of Biosciences, University of Kent , Canterbury, UK., Lehman W; Department of Pharmacology, Physiology and Biophysics, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Publikováno v: The Journal of general physiology [J Gen Physiol] 2024 May 06; Vol. 156 (5). Date of Electronic Publication: 2024 Apr 12.
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2
Akademický článek
Molecular Mechanisms of Deregulation of Muscle Contractility Caused by the R168H Mutation in TPM3 and Its Attenuation by Therapeutic Agents.
Autor: Karpicheva OE; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg 194064, Russia., Avrova SV; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg 194064, Russia., Bogdanov AL; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg 194064, Russia., Sirenko VV; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg 194064, Russia., Redwood CS; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK., Borovikov YS; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg 194064, Russia.
Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 18; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 18.
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3
Akademický článek
Molecular Mechanisms of the Deregulation of Muscle Contraction Induced by the R90P Mutation in Tpm3.12 and the Weakening of This Effect by BDM and W7.
Autor: Borovikov YS; Laboratory of Molecular Basis of Cell Motility, Institute of Cytology of the Russian Academy of Sciences, 4 Tikhoretsky Ave., 194064 Saint Petersburg, Russia., Andreeva DD; Laboratory of Molecular Basis of Cell Motility, Institute of Cytology of the Russian Academy of Sciences, 4 Tikhoretsky Ave., 194064 Saint Petersburg, Russia., Avrova SV; Laboratory of Molecular Basis of Cell Motility, Institute of Cytology of the Russian Academy of Sciences, 4 Tikhoretsky Ave., 194064 Saint Petersburg, Russia., Sirenko VV; Laboratory of Molecular Basis of Cell Motility, Institute of Cytology of the Russian Academy of Sciences, 4 Tikhoretsky Ave., 194064 Saint Petersburg, Russia., Simonyan AO; Laboratory of Molecular Basis of Cell Motility, Institute of Cytology of the Russian Academy of Sciences, 4 Tikhoretsky Ave., 194064 Saint Petersburg, Russia., Redwood CS; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK., Karpicheva OE; Laboratory of Molecular Basis of Cell Motility, Institute of Cytology of the Russian Academy of Sciences, 4 Tikhoretsky Ave., 194064 Saint Petersburg, Russia.
Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Jun 12; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 12.
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4
Akademický článek
Looking for Targets to Restore the Contractile Function in Congenital Myopathy Caused by Gln 147 Pro Tropomyosin.
Autor: Karpicheva OE; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., 194064 St. Petersburg, Russia., Simonyan AO; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., 194064 St. Petersburg, Russia.; Department of Biophysics, Faculty of Biology, Saint Petersburg State University, 7/9 Universitetskaya Emb., 199034 St. Petersburg, Russia., Rysev NA; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., 194064 St. Petersburg, Russia., Redwood CS; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK., Borovikov YS; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., 194064 St. Petersburg, Russia.
Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 14; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 14.
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5
Akademický článek
Molecular Mechanisms of Muscle Weakness Associated with E173A Mutation in Tpm3.12. Troponin Ca 2+ Sensitivity Inhibitor W7 Can Reduce the Damaging Effect of This Mutation.
Autor: Borovikov YS; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., 194064 St. Petersburg, Russia., Simonyan AO; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., 194064 St. Petersburg, Russia., Avrova SV; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., 194064 St. Petersburg, Russia., Sirenko VV; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., 194064 St. Petersburg, Russia., Redwood CS; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK., Karpicheva OE; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., 194064 St. Petersburg, Russia.
Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 Jun 22; Vol. 21 (12). Date of Electronic Publication: 2020 Jun 22.
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6
Akademický článek
The molecular mechanism of muscle dysfunction associated with the R133W mutation in Tpm2.2.
Autor: Borovikov YS; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg, 194064, Russia. Electronic address: borovikov@incras.ru., Karpicheva OE; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg, 194064, Russia., Avrova SV; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg, 194064, Russia., Simonyan AO; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg, 194064, Russia., Sirenko VV; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg, 194064, Russia., Redwood CS; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom.
Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Feb 26; Vol. 523 (1), pp. 258-262. Date of Electronic Publication: 2019 Dec 19.
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7
Akademický článek
The molecular mechanisms of a high Ca 2+ -sensitivity and muscle weakness associated with the Ala155Thr substitution in Tpm3.12.
Autor: Avrova SV; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Avenue, St. Petersburg, 194064, Russia., Karpicheva OE; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Avenue, St. Petersburg, 194064, Russia., Simonyan AO; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Avenue, St. Petersburg, 194064, Russia., Sirenko VV; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Avenue, St. Petersburg, 194064, Russia., Redwood CS; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom., Borovikov YS; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Avenue, St. Petersburg, 194064, Russia. Electronic address: borovikov@incras.ru.
Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2019 Jul 23; Vol. 515 (2), pp. 372-377. Date of Electronic Publication: 2019 May 30.
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8
Akademický článek
The Primary Causes of Muscle Dysfunction Associated with the Point Mutations in Tpm3.12; Conformational Analysis of Mutant Proteins as a Tool for Classification of Myopathies.
Autor: Borovikov YS; Institute of Cytology of the Russian Academy of Sciences, Laboratory of Molecular Basis of Cell Motility, 4 Tikhoretsky Ave., 194064 Saint Petersburg, Russia, olexiya6@ya.ru (O.E.K.). borovikov@incras.ru., Karpicheva OE; Institute of Cytology of the Russian Academy of Sciences, Laboratory of Molecular Basis of Cell Motility, 4 Tikhoretsky Ave., 194064 Saint Petersburg, Russia, olexiya6@ya.ru (O.E.K.). olexiya6@ya.ru., Simonyan AO; Institute of Cytology of the Russian Academy of Sciences, Laboratory of Molecular Basis of Cell Motility, 4 Tikhoretsky Ave., 194064 Saint Petersburg, Russia, olexiya6@ya.ru (O.E.K.). simonyan_armen@mail.ru.; Saint Petersburg State University, Faculty of Biology, Department of Biophysics, 7/9 Universitetskaya Emb., 199034 Saint Petersburg, Russia. simonyan_armen@mail.ru., Avrova SV; Institute of Cytology of the Russian Academy of Sciences, Laboratory of Molecular Basis of Cell Motility, 4 Tikhoretsky Ave., 194064 Saint Petersburg, Russia, olexiya6@ya.ru (O.E.K.). avrova@rambler.ru., Rogozovets EA; Institute of Cytology of the Russian Academy of Sciences, Laboratory of Molecular Basis of Cell Motility, 4 Tikhoretsky Ave., 194064 Saint Petersburg, Russia, olexiya6@ya.ru (O.E.K.). elena.rogozovec@gmail.com., Sirenko VV; Institute of Cytology of the Russian Academy of Sciences, Laboratory of Molecular Basis of Cell Motility, 4 Tikhoretsky Ave., 194064 Saint Petersburg, Russia, olexiya6@ya.ru (O.E.K.). sirw@mail.ru., Redwood CS; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK. credwood@well.ox.ac.uk.
Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2018 Dec 10; Vol. 19 (12). Date of Electronic Publication: 2018 Dec 10.
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9
Akademický článek
The reason for the low Ca 2+ -sensitivity of thin filaments associated with the Glu41Lys mutation in the TPM2 gene is "freezing" of tropomyosin near the outer domain of actin and inhibition of actin monomer switching off during the ATPase cycle.
Autor: Avrova SV; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg, 194064, Russia., Karpicheva OE; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg, 194064, Russia., Rysev NA; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg, 194064, Russia., Simonyan AO; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg, 194064, Russia; Saint Petersburg State University, 7/9 Universitetskaya emb, St. Petersburg, 199034, Russia., Sirenko VV; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg, 194064, Russia., Redwood CS; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom., Borovikov YS; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Av., St. Petersburg, 194064, Russia. Electronic address: borovikov@incras.ru.
Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2018 Jul 12; Vol. 502 (2), pp. 209-214. Date of Electronic Publication: 2018 May 26.
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10
Akademický článek
The primary cause of muscle disfunction associated with substitutions E240K and R244G in tropomyosin is aberrant behavior of tropomyosin and response of actin and myosin during ATPase cycle.
Autor: Simonyan AO; Institute of Cytology of the Russian Academy of Sciences, Laboratory of Molecular Basis of Cell Motility, 4 Tikhoretsky Ave., 194064, Saint Petersburg, Russia; Saint Petersburg State University, Faculty of Biology, Department of Biophysics, 7/9 Universitetskaya Emb., 199034, Saint Petersburg, Russia., Sirenko VV; Institute of Cytology of the Russian Academy of Sciences, Laboratory of Molecular Basis of Cell Motility, 4 Tikhoretsky Ave., 194064, Saint Petersburg, Russia., Karpicheva OE; Institute of Cytology of the Russian Academy of Sciences, Laboratory of Molecular Basis of Cell Motility, 4 Tikhoretsky Ave., 194064, Saint Petersburg, Russia., Robaszkiewicz K; Kazimierz Wielki University in Bydgoszcz, Institute of Experimental Biology, Department of Biochemistry and Cell Biology, Ks. J. Poniatowski 12 Str., 85-671, Bydgoszcz, Poland., Śliwinska M; Kazimierz Wielki University in Bydgoszcz, Institute of Experimental Biology, Department of Biochemistry and Cell Biology, Ks. J. Poniatowski 12 Str., 85-671, Bydgoszcz, Poland., Moraczewska J; Kazimierz Wielki University in Bydgoszcz, Institute of Experimental Biology, Department of Biochemistry and Cell Biology, Ks. J. Poniatowski 12 Str., 85-671, Bydgoszcz, Poland., Krutetskaya ZI; Saint Petersburg State University, Faculty of Biology, Department of Biophysics, 7/9 Universitetskaya Emb., 199034, Saint Petersburg, Russia., Borovikov YS; Institute of Cytology of the Russian Academy of Sciences, Laboratory of Molecular Basis of Cell Motility, 4 Tikhoretsky Ave., 194064, Saint Petersburg, Russia. Electronic address: borovikov@incras.ru.
Publikováno v: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2018 Apr 15; Vol. 644, pp. 17-28. Date of Electronic Publication: 2018 Mar 03.
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