Tezepelumab Reduces Exacerbations Across All Seasons in Patients with Severe, Uncontrolled Asthma: A Post Hoc Analysis of the PATHWAY Phase 2b Study

Autor: Corren J, Karpefors M, Hellqvist Å, Parnes JR, Colice G

Publikováno v: Journal of Asthma and Allergy, Vol Volume 14, Pp 1-11 (2021)

Jonathan Corren,1 Martin Karpefors,2 Åsa Hellqvist,3 Jane R Parnes,4 Gene Colice5 1Departments of Medicine and Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA; 2Data Science and AI, AstraZeneca, Gothenburg

Externí odkaz: https://doaj.org/article/85c2e1a80c26407ca56b966e3aea265a

Development and Validation of a New Hierarchical Composite End Point for Clinical Trials of Kidney Disease Progression.

Autor: Heerspink HJL; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; The George Institute for Global Health, Sydney, New South Wales, Australia., Jongs N; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Schloemer P; Pharmaceuticals, Research and Development, Bayer AG, Berlin, Germany., Little DJ; Late Stage Development, Cardiovascular, Renal and Metabolism (CVRM), Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland., Brinker M; Pharmaceuticals, Research and Development, Bayer AG, Wuppertal, Germany., Tasto C; Pharmaceuticals, Research and Development, Bayer AG, Wuppertal, Germany., Karpefors M; Late Stage Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Wheeler DC; The George Institute for Global Health, Sydney, New South Wales, Australia.; Department of Renal Medicine, University College London, London, United Kingdom., Bakris G; Department of Medicine, University of Chicago Medicine, Chicago, Illinois., Perkovic V; The George Institute for Global Health, Sydney, New South Wales, Australia.; Faculty of Medicine & Health, University New South Wales, Sydney, New South Wales, Australia., Nkulikiyinka R; Pharmaceuticals, Research and Development, Bayer AG, Berlin, Germany., Rossert J; Late Stage Development, Cardiovascular, Renal and Metabolism (CVRM), Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland., Gasparyan SB; Late Stage Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.

Publikováno v: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2023 Dec 01; Vol. 34 (12), pp. 2025-2038. Date of Electronic Publication: 2023 Oct 24.

The maraca plot: A novel visualization of hierarchical composite endpoints.

Autor: Karpefors M; Late Stage Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Lindholm D; Late Stage Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Gasparyan SB; Late Stage Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.

Publikováno v: Clinical trials (London, England) [Clin Trials] 2023 Feb; Vol. 20 (1), pp. 84-88. Date of Electronic Publication: 2022 Nov 14.

Bioimpedance spectroscopy: a new tool to assess early esophageal changes linked to gastroesophageal reflux disease?

Autor: Lundin, P.¹, Karpefors, M.¹, Carlsson, K.¹, Hansen, M. B.¹, Ruth, M.¹

Publikováno v: Diseases of the Esophagus. Sep2011, Vol. 24 Issue 7, p462-469. 8p. 1 Color Photograph, 1 Diagram, 1 Chart, 3 Graphs.

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