Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Karosham D. Reddy"'
Autor:
Brian G Oliver, Xiaomin Huang, Rochelle Yarak, Xu Bai, Qi Wang, Razia Zakarya, Karosham D. Reddy, Chantal Donovan, Richard Y. Kim, James Morkaya, Baoming Wang, Yik Lung Chan, Sonia Saad, Alen Faiz, David van Reyk, Alexei Verkhratsky, Chenju Yi, Hui Chen
Publikováno v:
Environment International, Vol 191, Iss , Pp 108971- (2024)
There is no safe level of air pollution for human health. Traffic-related particulate matter (PM2.5) is a major in-utero toxin, mechanisms of action of which are not fully understood. BALB/c dams were exposed to an Australian level of traffic PM2.5 (
Externí odkaz:
https://doaj.org/article/6fca2a75557a4402bb948d62629d5789
Autor:
Sandra Rutting, Dia Xenaki, Karosham D. Reddy, Melissa Baraket, David G. Chapman, Gregory G. King, Brian G. Oliver, Katrina O. Tonga
Publikováno v:
ERJ Open Research, Vol 7, Iss 2 (2021)
Externí odkaz:
https://doaj.org/article/1889e3bc570e4ee6927c64fa3217132c
Autor:
Karosham D. Reddy, Sandra Rutting, Katrina Tonga, Dikaia Xenaki, Jodie L. Simpson, Vanessa M. McDonald, Marshall Plit, Monique Malouf, Razia Zakarya, Brian G. Oliver
Publikováno v:
Physiological Reports, Vol 8, Iss 11, Pp n/a-n/a (2020)
Abstract Diverging susceptibility and severity in respiratory diseases is prevalent between males and females. Sex hormones have inconclusively been attributed as the cause of these differences, however, strong evidence exists promoting genetic facto
Externí odkaz:
https://doaj.org/article/cefb75438fc74cb9b44ab18a4686e8f2
Autor:
Karosham D. Reddy, Sandra Rutting, Corry-Anke Brandsma, Dikaia Xenaki, Jack Bozier, Brian G. Oliver, Yik Lung Chan, Hui Chen, Razia Zakarya, Ian M. Adcock, Roy R Woldhuis, David Van Ly
Publikováno v:
Thorax, 76(7), 647-655. BMJ PUBLISHING GROUP
RationaleIn COPD, small airway fibrosis occurs due to increased extracellular matrix (ECM) deposition in and around the airway smooth muscle (ASM) layer. Studies of immune cells and peripheral lung tissue have shown that epigenetic changes occur in C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f3909db847312782e8864b7f87650a
https://hdl.handle.net/11370/27cc7406-4155-4cac-95b0-f7016b66b1b5
https://hdl.handle.net/11370/27cc7406-4155-4cac-95b0-f7016b66b1b5
Autor:
Alen Faiz, Karosham D. Reddy, Andy Lan, Hananeh Aliee, Ilse M. Boudewijn, Maarten van den Berge, Gerard H. Koppelman, Fabian J. Theis, Brian G. Oliver, Senani N. H. Rathnayake
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Am. J. Respir. Cell Mol. Biol. 65, 366-377 (2021)
Am. J. Respir. Cell Mol. Biol. 65, 366-377 (2021)
Current smoking contributes to worsened asthma prognosis and more severe symptoms and limits the beneficial effects of corticosteroids. As the nasal epithelium can reflect smoking-induced changes in the lower airways, it is a relevant source to inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c27ce5704eb8a2352455e9fc08b3877
https://hdl.handle.net/10453/154338
https://hdl.handle.net/10453/154338
Autor:
Andy Lan, Karosham D. Reddy, Ilse M. Boudewijn, Alen Faiz, Gerard H. Koppelman, Brian G. Oliver, Senani N. H. Rathnayake, M. van den Berge
Publikováno v:
06.04 - Genes and environment.
Current-smoking significantly contributes to worse asthma prognosis and more severe disease symptoms. Smoking limits the beneficial effects of corticosteroids by altering the physiological response in the airways. The nasal epithelium is a relevant s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09867dea15f29995426fe0954cfe204a
https://doi.org/10.1183/23120541.lsc-2021.47
https://doi.org/10.1183/23120541.lsc-2021.47
Autor:
Brian G. Oliver, Karosham D. Reddy, Sandra Rutting, Melissa Baraket, Gregory G. King, Katrina O. Tonga, David G. Chapman, Dia Xenaki
Publikováno v:
ERJ Open Research
article-version (VoR) Version of Record
ERJ Open Research, Vol 7, Iss 2 (2021)
article-version (VoR) Version of Record
ERJ Open Research, Vol 7, Iss 2 (2021)
Asthma is characterised by recurrent symptoms associated with variable airflow obstruction and airway hyperresponsiveness, all of which are improved with combination inhaled corticosteroid (ICS)/long-acting β-agonist (LABA) treatment in mild-to-mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e002f33ff4b1ccd2ae589f1d10ff2869
https://pubmed.ncbi.nlm.nih.gov/34084782
https://pubmed.ncbi.nlm.nih.gov/34084782
Autor:
Brian G. Oliver, Karosham D. Reddy
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 320(1)
Tobacco smoke has harmful effects on a multiorgan level. Exposure to smoke, whether in utero or environmental, significantly increases susceptibility. This susceptibility has been identified to be divergent between males and females. However, there r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cafaae0d6074edf280ccc533d9d3daef
https://pubmed.ncbi.nlm.nih.gov/33084360
https://pubmed.ncbi.nlm.nih.gov/33084360
Autor:
Xin Nee Tew, Murtaza M. Tambuwala, Natalie Jia Xin Lau, Thiagarajan Madheswaran, Gaurav Gupta, Haribalan Perumalsamy, Alan Hsu, Philip M. Hansbro, Karosham D. Reddy, Brian G. Oliver, Peter A. B. Wark, Sri Renukadevi Balusamy, Farrukh Zeeshan, Dinesh Kumar Chellappan, Kamal Dua, Alaa A. A. Aljabali, Ridhima Wadhwa
Publikováno v:
Chemico-biological interactions. 317
© 2020 Inflammatory responses play a remarkable role in the mechanisms of acute and chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD), asthma, pulmonary fibrosis and lung cancer. Currently, there is a resurgence in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6394dc65fdc8fe7a3ffb4be7813fe6
https://pubmed.ncbi.nlm.nih.gov/31968208
https://pubmed.ncbi.nlm.nih.gov/31968208
Publikováno v:
Airway cell biology and immunopathology.
Background: Epigenetic modifications are closely linked to COPD as epigenetic inhibitors alter the expression of inflammatory mediators in non-COPD ASM, yet have no significant effect on COPD ASM cells, however, the nature of this alteration is uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f1d787bb7e566fa31321caa4ef04358
https://doi.org/10.1183/13993003.congress-2019.pa2413
https://doi.org/10.1183/13993003.congress-2019.pa2413