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pro vyhledávání: '"Karoly ED"'
Publikováno v:
Pesticide biochemistry and physiology. 55(2)
Azinphosmethyl-selected tufted apple bud moths were compared to susceptible and reverted strains with respect to possible metabolic mechanisms of resistance within the third instar, fifth instar, and adults. Based upon bioassays conducted by topical
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Autor:
Lotta, LA, Scott, RA, Sharp, SJ, Burgess, S, Luan, J, Tillin, T, Schmidt, AF, Imamura, F, Stewart, ID, Perry, JRB, Marney, L, Koulman, A, Karoly, ED, Forouhi, NG, Sjögren, RJO, Näslund, E, Zierath, Krook, A, Savage, DB, Griffin, JL, Chaturvedi, N, Hingorani, AD, Khaw, K-T, Barroso, I, McCarthy, MI, O'Rahilly, S, Wareham, NJ, Langenberg, C
$\textbf{BACKGROUND}$: Higher circulating levels of the branched-chain amino acids (BCAAs; i.e., isoleucine, leucine, and valine) are strongly associated with higher type 2 diabetes risk, but it is not known whether this association is causal. We und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59afca8834c6ec9c36694a81795608c5
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Autor:
Li VL; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Chemistry, Stanford University, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA., Xiao S; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA., Schlosser P; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Centre for Integrative Biological Signaling Studies (CIBSS), University of Freiburg, Freiburg, Germany., Scherer N; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany., Wiggenhorn AL; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Chemistry, Stanford University, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA., Spaas J; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA., Tung AS; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA., Karoly ED; Metabolon, Inc., Morrisville, NC, USA., Köttgen A; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Centre for Integrative Biological Signaling Studies (CIBSS), University of Freiburg, Freiburg, Germany., Long JZ; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA. jzlong@stanford.edu.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA. jzlong@stanford.edu.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA. jzlong@stanford.edu.; The Phil & Penny Knight Initiative for Brain Resilience at the Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA. jzlong@stanford.edu.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA. jzlong@stanford.edu.
Publikováno v:
Nature communications [Nat Commun] 2024 Aug 12; Vol. 15 (1), pp. 6895. Date of Electronic Publication: 2024 Aug 12.
Autor:
Schlosser P; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany. pascal.schlosser@uniklinik-freiburg.de.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. pascal.schlosser@uniklinik-freiburg.de., Scherer N; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine, University of Freiburg, Freiburg, Germany., Grundner-Culemann F; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany., Monteiro-Martins S; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany., Haug S; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany., Steinbrenner I; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany., Uluvar B; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany., Wuttke M; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany., Cheng Y; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany., Ekici AB; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Gyimesi G; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, University of Bern, Bern, Switzerland., Karoly ED; Metabolon, Inc., Morrisville, NC, USA., Kotsis F; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.; Department of Medicine IV-Nephrology and Primary Care, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany., Mielke J; Research and Early Development, Pharmaceuticals Division, Bayer AG, Wuppertal, Germany., Gomez MF; Department of Clinical Sciences in Malmö, Lund University Diabetes Centre, Lund University, Lund, Sweden., Yu B; Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Grams ME; New York University Grossman School of Medicine, New York, NY, USA., Coresh J; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Boerwinkle E; Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Köttgen M; Department of Medicine IV-Nephrology and Primary Care, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.; Centre for Integrative Biological Signalling Studies (CIBSS), Albert-Ludwigs-University Freiburg, Freiburg, Germany., Kronenberg F; Institute of Genetic Epidemiology, Department of Genetics, Medical University of Innsbruck, Innsbruck, Austria., Meiselbach H; Department of Nephrology and Hypertension, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Mohney RP; Metabolon, Inc., Morrisville, NC, USA., Akilesh S; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Schmidts M; Centre for Integrative Biological Signalling Studies (CIBSS), Albert-Ludwigs-University Freiburg, Freiburg, Germany.; Freiburg University Faculty of Medicine, Center for Pediatrics and Adolescent Medicine, University Hospital Freiburg, Freiburg, Germany., Hediger MA; Membrane Transport Discovery Lab, Department of Nephrology and Hypertension and Department of Biomedical Research, University of Bern, Bern, Switzerland., Schultheiss UT; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.; Department of Medicine IV-Nephrology and Primary Care, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany., Eckardt KU; Department of Nephrology and Hypertension, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany., Oefner PJ; Institute of Functional Genomics, University of Regensburg, Regensburg, Germany., Sekula P; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany., Li Y; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany., Köttgen A; Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany. anna.koettgen@uniklinik-freiburg.de.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. anna.koettgen@uniklinik-freiburg.de.; Centre for Integrative Biological Signalling Studies (CIBSS), Albert-Ludwigs-University Freiburg, Freiburg, Germany. anna.koettgen@uniklinik-freiburg.de.
Publikováno v:
Nature genetics [Nat Genet] 2023 Jun; Vol. 55 (6), pp. 995-1008. Date of Electronic Publication: 2023 Jun 05.
Autor:
Hysi PG; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.; NIHR Biomedical Research Centre at Guy's and St. Thomas' Foundation Trust, London SE1 9RT, UK., Christofidou P; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Falchi M; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Karoly ED; Discovery and Translational Sciences, Metabolon Inc., Raleigh-Durham, NC 27560, USA., Nihr Bioresource Investigators, Mohney RP; Discovery and Translational Sciences, Metabolon Inc., Raleigh-Durham, NC 27560, USA., Valdes AM; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.; Inflammation, Injury and Recovery Sciences, School of Medicine, University of Nottingham, Nottingham NG5 1PB, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.
Publikováno v:
Metabolites [Metabolites] 2022 Jan 11; Vol. 12 (1). Date of Electronic Publication: 2022 Jan 11.