Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Karolis, Bauza"'
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0209028 (2019)
Malaria remains one the world's most deadly infectious diseases, with almost half a million deaths and over 150 million clinical cases each year. An effective vaccine would contribute enormously to malaria control and will almost certainly be require
Externí odkaz:
https://doaj.org/article/175723a0c35746cdaae9e0716f090788
Autor:
DO Nicole Sbircea, Rola Khedraki, Jared J Herr, Benjamin D’Souza, Stephanie Hsiao, Jasen L. Gilge, Parin J. Patel, Daniel J. Cantillon, Ajay Srivastava, S. Ahmed, Farooq H. Sheikh, Ashwin Ravichandran, Michael Z Tong, Karolis Bauza
Publikováno v:
JACC: Clinical Electrophysiology. 7:494-501
Objectives The objective of this study was to describe the risk of cardiac implantable electronic devices (CIEDs) complications in patients with left ventricular assist devices (LVADs). Background Patients with LVADs are predisposed to ventricular ar
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119880 (2015)
The development of an efficacious vaccine against the Plasmodium parasite remains a top priority. Previous research has demonstrated the ability of a prime-boost virally vectored sub-unit vaccination regimen, delivering the liver-stage expressed mala
Externí odkaz:
https://doaj.org/article/1b1500385c5042ae9ae5d2d1e9f3a8c5
Autor:
Julius Clemence R Hafalla, Karolis Bauza, Johannes Friesen, Gloria Gonzalez-Aseguinolaza, Adrian V S Hill, Kai Matuschewski
Publikováno v:
PLoS Pathogens, Vol 9, Iss 5, p e1003303 (2013)
CD8⁺ T cells mediate immunity against Plasmodium liver stages. However, the paucity of parasite-specific epitopes of CD8⁺ T cells has limited our current understanding of the mechanisms influencing the generation, maintenance and efficiency of th
Externí odkaz:
https://doaj.org/article/4d95f7aaadd14d57bfcbed37a7cc86d1
Autor:
Olivier Silvie, Katja Müller, Matthew P. Gibbins, Elyzana Dewi Putrianti, Kai Matuschewski, Julius C. R. Hafalla, Karolis Bauza, Maya Glover, Arturo Reyes-Sandoval, Jasmine Liu
Publikováno v:
Infection and Immunity
Infection and Immunity, 2020, 88 (10), ⟨10.1128/IAI.00383-20⟩
Infection and Immunity, 2020, 88 (10), ⟨10.1128/IAI.00383-20⟩
The circumsporozoite protein (CSP) builds up the surface coat of sporozoites and is the leading malaria pre-erythrocytic-stage vaccine candidate. CSP has been shown to induce robust CD8+ T cell responses that are capable of eliminating developing par
Autor:
Matthew P, Gibbins, Katja, Müller, Maya, Glover, Jasmine, Liu, Elyzana D, Putrianti, Karolis, Bauza, Arturo, Reyes-Sandoval, Kai, Matuschewski, Olivier, Silvie, Julius Clemence R, Hafalla
Publikováno v:
Infect Immun
The circumsporozoite protein (CSP) builds up the surface coat of sporozoites and is the leading malaria pre-erythrocytic-stage vaccine candidate. CSP has been shown to induce robust CD8(+) T cell responses that are capable of eliminating developing p
Autor:
Karolis Bauza, Tomas Malinauskas, Arturo Reyes-Sandoval, Erwan Atcheson, Andrew M. Blagborough
Publikováno v:
Infection and Immunity
The leading malaria vaccine candidate, RTS,S, based on the Plasmodium falciparum circumsporozoite protein (CSP), will likely be the first publicly adopted malaria vaccine. However, this and other subunit vaccines, such as virus-vectored thrombospondi
Publikováno v:
Journal of Evidence-Based Medicine. 8:108-110
In post-Soviet countries, where medical practice largely relies on experience alone, the incorporation of the best research evidence in clinical practice is limited. In order to promote the awareness and utilization of evidence-based medicine (EBM) a
Publikováno v:
Current hypertension reports. 18(4)
Persistently raised blood pressure is one of the major risk factors for diseases such as myocardial infarction and stroke. Uncontrolled hypertension is also associated with high rates of mortality, particularly in middle and high-income countries. Li
Autor:
Karolis Bauza, Adrian V. S. Hill, Matthew D. J. Dicks, Anita Milicic, Arturo Reyes-Sandoval, Christine S. Rollier, Choon-Kit Tang, David H. Wyllie, Rhea J. Longley, Dong Wang, Matthew G. Cottingham
Publikováno v:
Molecular Therapy
Substantial protection can be provided against the pre-erythrocytic stages of malaria by vaccination first with an adenoviral and then with an modified vaccinia virus Ankara (MVA) poxviral vector encoding the same ME.TRAP transgene. We investigated w