Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Karoline W Schjetne"'
Autor:
Peter Hillemanns, Agnieszka Denecke, Linn Woelber, Gerd Böhmer, Matthias Jentschke, Karoline W. Schjetne, Karsten M.H. Bruins Slot, Agnete B. Fredriksen
Publikováno v:
Clinical Cancer Research. 28:4885-4892
Purpose: To evaluate the safety, immunogenicity and efficacy of a therapeutic DNA vaccine VB10.16, using a unique modular vaccine technology that is based on linking antigens to CCL3L1 targeting module, in women with HPV16-positive high-grade cervica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a995d82fc8dff51aa6981e29f15129bf
https://doi.org/10.1158/1078-0432.ccr-22-1927
https://doi.org/10.1158/1078-0432.ccr-22-1927
Autor:
Agnete B. Fredriksen, Karsten M.H. Bruins Slot, Karoline W. Schjetne, Matthias Jentschke, Gerd Böhmer, Linn Woelber, Agnieszka Denecke, Peter Hillemanns
Supplementary Data from A Therapeutic Antigen-Presenting Cell-Targeting DNA Vaccine VB10.16 in HPV16-Positive High-Grade Cervical Intraepithelial Neoplasia: Results from a Phase I/IIa Trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a42f3ff036cc9a0d25a854da0517577
https://doi.org/10.1158/1078-0432.22488869.v1
https://doi.org/10.1158/1078-0432.22488869.v1
Autor:
Agnete B. Fredriksen, Karsten M.H. Bruins Slot, Karoline W. Schjetne, Matthias Jentschke, Gerd Böhmer, Linn Woelber, Agnieszka Denecke, Peter Hillemanns
Supplementary Figure from A Therapeutic Antigen-Presenting Cell-Targeting DNA Vaccine VB10.16 in HPV16-Positive High-Grade Cervical Intraepithelial Neoplasia: Results from a Phase I/IIa Trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b577f3150e3561d23b9021ff2990f0
https://doi.org/10.1158/1078-0432.22488866.v1
https://doi.org/10.1158/1078-0432.22488866.v1
Autor:
Agnete B. Fredriksen, Karsten M.H. Bruins Slot, Karoline W. Schjetne, Matthias Jentschke, Gerd Böhmer, Linn Woelber, Agnieszka Denecke, Peter Hillemanns
Purpose:To evaluate the safety, immunogenicity and efficacy of a therapeutic DNA vaccine VB10.16, using a unique modular vaccine technology that is based on linking antigens to CCL3L1 targeting module, in women with HPV16-positive high-grade cervical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fe19c6dd8e20bd98cea1f4fd0934ce
https://doi.org/10.1158/1078-0432.c.6532823.v1
https://doi.org/10.1158/1078-0432.c.6532823.v1
Autor:
Lene Støkken Høydahl, Karoline W. Schjetne, Inger Sandlie, Jan Terje Andersen, Inger Øynebråten, Terje Frigstad, Elin Lunde, Terje E. Michaelsen, Ingunn B. Rasmussen, Bjarne Bogen
Publikováno v:
Vaccine
Targeted delivery of antigen to antigen-presenting cells (APCs) enhances antigen presentation and thus, is a potent strategy for making more efficacious vaccines. This can be achieved by use of antibodies with specificity for endocytic surface molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfca19000ba70a4b2de1388d0c627cba
http://hdl.handle.net/10852/88729
http://hdl.handle.net/10852/88729
Autor:
Stine Granum, Monika Sekelja, Agnete Brunsvik Fredriksen, Audun Bersaas, Karoline W. Schjetne, Elisabeth Stubsrud, Helene Zell-Flagstad, Lise Madelene Skullerud
Publikováno v:
Cancer Research. 79:5003-5003
BACKGROUND: Recent advances in the field of cancer immunotherapy have identified CD8+ T cell responses against tumor-specific neoantigens as a key driver of tumor regression and prolonged survival. VB10.NEO is a highly potent DNA plasmid vaccine with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1c91e8aee5d7fa3c3203c8960260054
https://doi.org/10.1158/1538-7445.am2019-5003
https://doi.org/10.1158/1538-7445.am2019-5003
Autor:
Agnete Brunsvik Fredriksen, Anja Williams, Hedda Wold, Monika Sekelja, Karoline W. Schjetne, Mads Axelsen, Elke Jager, Lisa Gerner, Jürgen Krauss, Angela M. Krackhardt
Publikováno v:
Cancer Research. 79:CT217-CT217
BACKGROUND: Neoantigens are ideal for developing personalized cancer vaccines as they are tumor specific and not subject to central tolerance. Targeting neoantigens to generate potent tumor-specific T-cell responses has shown both promising preclinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::feb7da603394a0832fd6cec6ec7bac3b
https://doi.org/10.1158/1538-7445.am2019-ct217
https://doi.org/10.1158/1538-7445.am2019-ct217
Autor:
Elisabeth Stubsrud, Irene Skjørestad, Agnete Brunsvik Fredriksen, Linn Woelber, Peter Hillemanns, Mads Axelsen, Karoline W. Schjetne, Karl Ulrich Petry, Gerd Böhmer
Publikováno v:
Cancer Research. 79:CT209-CT209
BACKGROUND: Persistent HPV infection can lead to high-grade squamous intraepithelial lesions (HSIL) in cervical cells; current treatments are exclusively ablative which can lead to long-term reproductive morbidity. VB10.16, an investigational immunot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da84319cf669f6f204bebde01e0bba1e
https://doi.org/10.1158/1538-7445.am2019-ct209
https://doi.org/10.1158/1538-7445.am2019-ct209
Autor:
Audun Bersaas, Stine Granum, Jonathan Zalevsky, Lise Madelene Skullerud, Agnete Brunsvik Fredriksen, Helene Zell-Flagstad, Elisabeth Müller, Karoline W. Schjetne, Mads Axelsen
Publikováno v:
Cancer Research. 79:2256-2256
BACKGROUND: VB10.NEO is a highly potent DNA plasmid vaccine with intrinsic adjuvant effect designed for efficient delivery of personalized neoepitopes and is currently being tested in combination with CPI in patients with advanced solid tumors. NKTR-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83ef4a106688c188e61c7bc5a73df121
https://doi.org/10.1158/1538-7445.am2019-2256
https://doi.org/10.1158/1538-7445.am2019-2256
Autor:
Anne Spurkland, Monika Forsbring, Øyvind Molberg, Vibeke Sundvold-Gjerstad, Karl Schenck, Hans Christian Aasheim, Kristin M. Kolltveit, Karoline W. Schjetne, B. Bogen, Stine Granum, Ke Zheng Dai, Finn-Eirik Johansen, Virginia Smith Shapiro
Publikováno v:
Molecular Immunology. 45:2380-2390
The T-cell specific adapter protein (TSAd) encoded by the SH2D2A gene is up-regulated in activated human CD4+ T-cells in a cAMP-dependent manner. Expression of SH2D2A is important for proper activation of T-cells. Here, we show that SH2D2A expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26649224488eedd31d1cc3192d14bd50
https://doi.org/10.1016/j.molimm.2007.11.005
https://doi.org/10.1016/j.molimm.2007.11.005