Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Karolina Wojtowicz"'
Autor:
Justyna Borucka, Karolina Sterzyńska, Dominika Kaźmierczak, Monika Świerczewska, Marta Nowacka, Karolina Wojtowicz, Andrzej Klejewski, Michał Nowicki, Maciej Zabel, Rodryg Ramlau, Radosław Januchowski
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 150, Iss , Pp 113036- (2022)
Background: Inherent or developed during treatment drug resistance is the main reason for the low effectiveness of chemotherapy in ovarian cancer. IFI16 is a cytoplasmic/nuclear protein involved in response to virus’s infection and cell cycle arres
Externí odkaz:
https://doaj.org/article/96790802d1314629a17a53e7d0bb4d57
Publikováno v:
Cellular & Molecular Biology Letters, Vol 25, Iss 1, Pp 1-17 (2020)
Abstract The plasma membrane (PM) spatiotemporal organization is one of the major factors controlling cell signaling and whole-cell homeostasis. The PM lipids, including cholesterol, determine the physicochemical properties of the membrane bilayer an
Externí odkaz:
https://doaj.org/article/3ab2981056cc4ff5bf1ea3b7c65bbf96
Autor:
Karolina Wojtowicz, Karolina Sterzyńska, Monika Świerczewska, Michał Nowicki, Maciej Zabel, Radosław Januchowski
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 4243 (2021)
Our goal was to examine the anticancer effects of piperine against the resistant human ovarian cancer cells and to explore the molecular mechanisms responsible for its anticancer effects. Our study used drug-sensitive ovarian cancer cell line W1 and
Externí odkaz:
https://doaj.org/article/bce1afed4faa4879a1393d8db2b539f0
Autor:
Agnieszka Krawczenko, Aleksandra Bielawska-Pohl, Karolina Wojtowicz, Roksana Jura, Maria Paprocka, Elżbieta Wojdat, Urszula Kozłowska, Aleksandra Klimczak, Catherine Grillon, Claudine Kieda, Danuta Duś
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172371 (2017)
Active cellular transporters of harmful agents-multidrug resistance (mdr) proteins-are present in tumor, stem and endothelial cells, among others. While mdr proteins are broadly studied in tumor cells, their role in non-tumor cells and the significan
Externí odkaz:
https://doaj.org/article/cf337ee4ecbe4e699ea2d1dfa84b31ab
Autor:
Karolina Sterzyńska, Dominika Kaźmierczak, Andrzej Klejewski, Monika Świerczewska, Karolina Wojtowicz, Marta Nowacka, Jacek Brązert, Michał Nowicki, Radosław Januchowski
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 16, p 3927 (2019)
One of the main obstacles to the effective treatment of ovarian cancer patients continues to be the drug resistance of cancer cells. Osteoblast-Specific Factor 2 (OSF-2, Periostin) is a secreted extracellular matrix protein (ECM) expressed in fibrobl
Externí odkaz:
https://doaj.org/article/3278793e41dc45a1884cbd700614c830
Autor:
Monika Świerczewska, Karolina Sterzyńska, Karolina Wojtowicz, Dominika Kaźmierczak, Dariusz Iżycki, Michał Nowicki, Maciej Zabel, Radosław Januchowski
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 8, p 2053 (2019)
Background: Ovarian cancer is the 7th most common cancer and 8th most mortal cancer among woman. The standard treatment includes cytoreduction surgery followed by chemotherapy. Unfortunately, in most cases, after treatment, cancer develops drug resis
Externí odkaz:
https://doaj.org/article/044fb1ef8d084d3490f93e6c7d2ffe18
Autor:
Karolina Sterzyńska, Andrzej Klejewski, Karolina Wojtowicz, Monika Świerczewska, Marta Nowacka, Dominika Kaźmierczak, Małgorzata Andrzejewska, Damian Rusek, Maciej Brązert, Jacek Brązert, Michał Nowicki, Radosław Januchowski
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 54 (2018)
A major contributor leading to treatment failure of ovarian cancer patients is the drug resistance of cancer cell. CSCs- (cancer stem cells) and ECM (extracellular matrix)-related models of drug resistance are described as independently occurring in
Externí odkaz:
https://doaj.org/article/cd54d23e5dd54e4dbbcb1cc696e13a84
Autor:
Karolina Sterzyńska, Andrzej Klejewski, Karolina Wojtowicz, Monika Świerczewska, Małgorzata Andrzejewska, Damian Rusek, Maciej Sobkowski, Witold Kędzia, Jacek Brązert, Michał Nowicki, Radosław Januchowski
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2901 (2018)
The major cause of ovarian cancer treatment failure in cancer patients is inherent or acquired during treatment drug resistance of cancer. Matrix Gla protein (MGP) is a secreted, non-collagenous extracellular matrix protein involved in inhibition of
Externí odkaz:
https://doaj.org/article/a1c4e2492def467db2df989c18736324
Autor:
Monika Świerczewska, Andrzej Klejewski, Karolina Wojtowicz, Maciej Brązert, Dariusz Iżycki, Michał Nowicki, Maciej Zabel, Radosław Januchowski
Publikováno v:
Molecules, Vol 22, Iss 10, p 1717 (2017)
Low efficiency of chemotherapy in ovarian cancer results from the development of drug resistance. Cisplatin (CIS) and topotecan (TOP) are drugs used in chemotherapy of this cancer. We analyzed the development of CIS and TOP resistance in ovarian canc
Externí odkaz:
https://doaj.org/article/de39d3fb4aa24f5c8dab11a3d00a4ebb
Autor:
Karolina Wojtowicz, Michał Nowicki
Publikováno v:
Biochemical and Biophysical Research Communications. 662:1-7