Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Karolina Sekeres"'
Autor:
Andrea Ruiz-Velasco, Min Zi, Susanne S Hille, Tayyiba Azam, Namrita Kaur, Juwei Jiang, Binh Nguyen, Karolina Sekeres, Pablo Binder, Lucy Collins, Fay Pu, Han Xiao, Kaomei Guan, Norbert Frey, Elizabeth J Cartwright, Oliver J Müller, Xin Wang, Wei Liu
Publikováno v:
eLife, Vol 9 (2020)
Myocardial insulin resistance contributes to heart failure in response to pathological stresses, therefore, a therapeutic strategy to maintain cardiac insulin pathways requires further investigation. We demonstrated that insulin receptor substrate 1
Externí odkaz:
https://doaj.org/article/e82f66576f0d4a39814f48fb1341eaf7
Autor:
Wei Liu, Juwei Jiang, Lucy Collins, Susanne Hille, Andrea Ruiz-Velasco, Namrita Kaur, Pablo Binder, Karolina Sekeres, Tayyiba Azam, Xin Wang, Min Zi, Oliver J. Müller, Elizabeth J. Cartwright, Han Xiao, Fay Pu, Kaomei Guan, Norbert Frey, Binh Yen Nguyen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ba7567770abf87b1a6279cc9f94c269
https://doi.org/10.7554/elife.54298.sa2
https://doi.org/10.7554/elife.54298.sa2
Autor:
Oliver J. Müller, Elizabeth J. Cartwright, Lucy Collins, Norbert Frey, Wei Liu, Binh Yen Nguyen, Pablo Binder, Min Zi, Karolina Sekeres, Tayyiba Azam, Xin Wang, Juwei Jiang, Namrita Kaur, Fay Pu, Kaomei Guan, Susanne Hille, Andrea Ruiz-Velasco, Han Xiao
Publikováno v:
eLife, Vol 9 (2020)
Myocardial insulin resistance contributes to heart failure in response to pathological stresses, therefore, a therapeutic strategy to maintain cardiac insulin pathways requires further investigation. We demonstrated that insulin receptor substrate 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29554f94d3e128937a936abe09884f0b
https://elifesciences.org/articles/54298
https://elifesciences.org/articles/54298
Autor:
Andrea, Ruiz-Velasco, Min, Zi, Susanne S, Hille, Tayyiba, Azam, Namrita, Kaur, Juwei, Jiang, Binh, Nguyen, Karolina, Sekeres, Pablo, Binder, Lucy, Collins, Fay, Pu, Han, Xiao, Kaomei, Guan, Norbert, Frey, Elizabeth J, Cartwright, Oliver J, Müller, Xin, Wang, Wei, Liu
Publikováno v:
eLife
Myocardial insulin resistance contributes to heart failure in response to pathological stresses, therefore, a therapeutic strategy to maintain cardiac insulin pathways requires further investigation. We demonstrated that insulin receptor substrate 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::024d48474d5a11a88ecf6db7245f35b4
https://pubmed.ncbi.nlm.nih.gov/32223896
https://pubmed.ncbi.nlm.nih.gov/32223896
Autor:
Susanne Kämmerer, Charlotte Schaeffer, Carola S. Mehnert, Stephanie M Schacht Wall, Karolina Sekeres, Ali El-Armouche, Stephan R Künzel, Manja Newe
Publikováno v:
Journal of Visualized Experiments.
Primary adult fibroblasts have become an important tool to study fibrosis, fibroblast interactions and inflammation in all body tissues. Since primary fibroblasts cannot divide indefinitely due to myofibroblast differentiation or senescence induction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2871ab63876dac6d09aef3db65679d8f
https://doi.org/10.3791/59858-v
https://doi.org/10.3791/59858-v
Autor:
Konrad Gruetzmann, Jan Dominik Kuhlmann, Manuel Mayr, Susanne Kaemmerer, Sems Malte Tugtekin, Stefan Rose-John, Natalie Herzog, Silvio Weber, Michael Wagner, Stefanie Meyer-Roxlau, Pauline Wimberger, Tomasz Kolanowski, Stephan R. Kuenzel, Karolina Sekeres, Kaomei Guan, Christopher Piorkowski, Ursula Ravens, Jan-Heiner Kuepper, Ali El-Armouche, Xiaoke Yin
Fibrosis and inflammation promote atrial fibrillation (AF) and worsen its clinical outcome. The underlying molecular mechanisms, that are relevant for effective antifibrotic drug development, are still under debate. This study deciphers a novel mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c674a9ab6aace1d5e12c87770ce27019
Autor:
Gabriela Salinas, Michael Stauske, Christof Lenz, Kaomei Guan, Karolina Sekeres, Gerd Hasenfuss, Lukas Cyganek, Wolfram-Hubertus Zimmermann, Malte Tiburcy, Sarah Henze, Kathleen Gerstenberg, Hanibal Bohnenberger
Publikováno v:
JCI Insight
Generation of homogeneous populations of subtype-specific cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) and their comprehensive phenotyping is crucial for a better understanding of the subtype-related disease mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba39658680f759e064256a2d922f58f
https://hdl.handle.net/21.11116/0000-0001-AB9A-121.11116/0000-0001-AB9E-D21.11116/0000-0001-AB9F-C21.11116/0000-0001-AB9C-F21.11116/0000-0001-AB9D-E
https://hdl.handle.net/21.11116/0000-0001-AB9A-121.11116/0000-0001-AB9E-D21.11116/0000-0001-AB9F-C21.11116/0000-0001-AB9C-F21.11116/0000-0001-AB9D-E
Autor:
Stefanie Meyer-Roxlau, Simon Lämmle, Annett Opitz, Stephan Künzel, Julius P. Joos, Stefan Neef, Karolina Sekeres, Samuel Sossalla, Friedrich Schöndube, Konstantin Alexiou, Lars S. Maier, Dobromir Dobrev, Kaomei Guan, Silvio Weber, Ali El-Armouche
Publikováno v:
Basic research in cardiology. 112(5)
Unfortunately, the author name Samuel Sossalla contained a typing error in the original publication. The original article has been corrected. We apologize for any inconvenience caused.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d606d9d73ee19170849439948c31bde
https://pubmed.ncbi.nlm.nih.gov/28597249
https://pubmed.ncbi.nlm.nih.gov/28597249
Autor:
Lars S. Maier, Stefan Neef, Kaomei Guan, Julius P. Joos, Silvio Weber, Ali El-Armouche, Simon Lämmle, Friedrich A. Schöndube, Samuel Sossalla, Annett Opitz, Konstantin Alexiou, Karolina Sekeres, Dobromir Dobrev, Stefanie Meyer-Roxlau, Stephan R Künzel
Publikováno v:
Basic Research in Cardiology. 112
Protein phosphatase 1 (PP1) is a key regulator of important cardiac signaling pathways. Dysregulation of PP1 has been heavily implicated in cardiac dysfunctions. Accordingly, pharmacological targeting of PP1 activity is considered for therapeutic int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78868f14a38122e74f003039bb57b26e
https://doi.org/10.1007/s00395-017-0635-0
https://doi.org/10.1007/s00395-017-0635-0
Autor:
Elisabeth M. Zeisberg, Tim Seidler, Karolina Sekeres, Kaomei Guan, Belal A. Mohamed, Stephan E. Lehnart, Michael Didié, Niels Voigt, Nico Hartmann, Stefan Luther, Karl Toischer, Lars Kattner, P Tirilomis, Gerd Hasenfuss, Wener Li, Stefan Neef, Samuel Sossalla, Claudia Richter, Jan D. Schmitto
Publikováno v:
Science translational medicine. 10(458)
Increased sarcoplasmic reticulum (SR) Ca2+ leak via the cardiac ryanodine receptor (RyR2) has been suggested to play a mechanistic role in the development of heart failure (HF) and cardiac arrhythmia. Mice treated with a selective RyR2 stabilizer, ry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044a28cdf6ba871d0c703fd25c761745
https://pubmed.ncbi.nlm.nih.gov/30626713
https://pubmed.ncbi.nlm.nih.gov/30626713