Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Karolina R. Gonçalves"'
Autor:
Ana Lia Mazzeti, Karolina R. Gonçalves, Patrícia Ferreira Boasquívis, Jamile Barbosa, Bruno G. Pereira, Maria de Nazaré Correia Soeiro, Vanessa Carla Furtado Mosqueira, Maria Terezinha Bahia
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1126 (2023)
Benznidazole (BZ) tablets are the currently prescribed treatment for Chagas disease. However, BZ presents limited efficacy and a prolonged treatment regimen with dose-dependent side effects. The design and development of new BZ subcutaneous (SC) impl
Externí odkaz:
https://doaj.org/article/fe3dca29a4dd4ee6a2e82586b06e2304
Autor:
Lívia de Figueiredo Diniz, Karolina R. Gonçalves, Dario Elias Pereira, Suianne Leticia Antunes Mota, Maria Terezinha Bahia, Ana Lia Mazzeti
Publikováno v:
Parasitology. 148:1320-1327
Drug combinations have been evaluated for Chagas disease in an attempt to improve efficacy and safety. In this line, the objective of this work is to assess the effects of treatment with nitro drugs combinations using benznidazole (BZ) or nifurtimox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe410dda30cf1fda35faf9cc4b52d8db
https://doi.org/10.1017/s0031182021001001
https://doi.org/10.1017/s0031182021001001
Autor:
Jadel M Kratz, Karolina R Gonçalves, Lavínia MD Romera, Carolina Borsoi Moraes, Paula Bittencourt-Cunha, Sergio Schenkman, Eric Chatelain, Sergio Sosa-Estani
Publikováno v:
Memórias do Instituto Oswaldo Cruz, Volume: 117, Article number: e200501, Published: 23 MAY 2022
Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi. There is an urgent need for safe, effective, and accessible new treatments since the currently approved drugs have serious limitations. Drug developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b8b2af06a6ca34e48c8c088c47de41
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762022000100206&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762022000100206&lng=en&tlng=en
Autor:
Herbert B. Tanowitz, Mirelle Lomar Viana, Karolina R. Gonçalves, Elisa L.B.C. Domingues, Maiara B. Narde, Farhad M Amjad, Maria Terezinha Bahia, Louis M. Weiss, Heberth de Paula, Wanderson Geraldo de Lima, Paul Zaki, Huan Huang, Fabiane Matos dos Santos, Philipp E Sherer
Publikováno v:
Parasitology Research. 119:1829-1843
The underlying pathogenic mechanisms of cardiomyopathy in Chagas disease are still unsolved. In order to better clarify the role of fat on the evolution of cardiomyopathy, the present study employed three murine models of chronic Trypanosoma cruzi in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f46ab297978acf26240250e7cc1fc256
https://doi.org/10.1007/s00436-020-06645-z
https://doi.org/10.1007/s00436-020-06645-z
Autor:
Karolina R. Gonçalves, Maria Terezinha Bahia, Huan Huang, Maiara B. Narde, Farhad M. Amjad, Fabiane Matos dos Santos, Mirelle Lomar Viana, Philipp E. Scherer, Louis M. Weiss, Herbert B. Tanowitz, Wanderson Geraldo de Lima, Paul Zaki, Elisa L.B.C. Domingues, Heberth de Paula
Publikováno v:
Parasitol Res
The underlying pathogenic mechanisms of cardiomyopathy in Chagas Disease are still unsolved. In order to better clarify the role of fat on the evolution of cardiomyopathy, the present study employed three murine models of chronic Trypanosoma cruzi in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e2131b50e196bad3c7112569db3b5a
https://pubmed.ncbi.nlm.nih.gov/32206887
https://pubmed.ncbi.nlm.nih.gov/32206887
Autor:
Álvaro Fernando da Silva do Nascimento, Maria Terezinha Bahia, Pollyanna Álvaro Spósito, Karolina R. Gonçalves, Isabela Ribeiro, Lívia de Figueiredo Diniz, Vanessa Carla Furtado Mosqueira, Ana Lia Mazzeti, George Luiz Lins Machado-Coelho
Publikováno v:
Biochemical Pharmacology. 148:213-221
Benznidazole and nifurtimox-treatments regimens currently used in human are supported by very limited experimental data. This study was designed to evaluate the time and dose dependence for efficacy of the most important nitroheterocyclic drugs in us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4d267d0629140ebcc3764799c0b335
https://doi.org/10.1016/j.bcp.2018.01.005
https://doi.org/10.1016/j.bcp.2018.01.005
Autor:
Mirelle Lomar Viana, Marcos Santos Zanini, Karolina R. Gonçalves, Wanderson Geraldo de Lima, Elisa Liz Belli Cassa Domingues, Maria Terezinha Bahia, Fabiane Matos dos Santos, Maiara B. Narde
Publikováno v:
Parasitology International. 83:102345
Chagas disease, caused by Trypanosoma cruzi, is a major neglected tropical disease that occurs mainly as chronic infection and systemic infection. Currently, there is no suitable and effective drug to treat this parasitic disease. Administration of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf65754943f98c715bb7dea05ab9cac
https://doi.org/10.1016/j.parint.2021.102345
https://doi.org/10.1016/j.parint.2021.102345
Autor:
Paul, Zaki, Elisa Lbc, Domingues, Farhad M, Amjad, Maiara B, Narde, Karolina R, Gonçalves, Mirelle L, Viana, Heberth, de Paula, Wanderson G, de Lima, Huan, Huang, Maria T, Bahia, Philipp E, Sherer, Fabiane M, Dos Santos, Louis M, Weiss, Herbert B, Tanowitz
Publikováno v:
Parasitology research. 119(6)
The underlying pathogenic mechanisms of cardiomyopathy in Chagas disease are still unsolved. In order to better clarify the role of fat on the evolution of cardiomyopathy, the present study employed three murine models of chronic Trypanosoma cruzi in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff7009ffd316131a62c7ce29bcf0d769
https://pubmed.ncbi.nlm.nih.gov/32307581
https://pubmed.ncbi.nlm.nih.gov/32307581
Autor:
Maria Terezinha Bahia, Vanessa Carla Furtado Mosqueira, Liliam Teixeira Oliveira, Ana Lia Mazzeti, Karolina R. Gonçalves, Géssica C. Schaun
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 145
Benznidazole (BZ) tablets are a unique form of treatment available for treating Chagas disease. Development of a liquid formulation containing BZ easy to administer orally for the treatment of paediatric patients, particularly for newborns is urgentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791b379d291be86b3a5abbb888ed81a3
https://pubmed.ncbi.nlm.nih.gov/31978590
https://pubmed.ncbi.nlm.nih.gov/31978590
Autor:
Karolina R. Gonçalves, Tassiane Assíria, Ruan Schott WonDollinger, Maria Terezinha Bahia, Isabela Ribeiro, Lívia de Figueiredo Diniz, Ana Lia Mazzeti
Publikováno v:
Antimicrobial Agents and Chemotherapy
Repositório Institucional da UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
Repositório Institucional da UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
Combination therapy has gained attention as a possible strategy for overcoming the limitations of the present therapeutic arsenal for Chagas disease. The aim of this study was to evaluate the effect of allopurinol in association with nitroheterocycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2284c1fd78d8d2da7145cff236b0360
http://europepmc.org/articles/PMC6535576
http://europepmc.org/articles/PMC6535576