Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Karolina Pulka-Ziach"'
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6806
Hybrids of short oligourea foldamers with residues of α, β and γ-amino acids esters at the C-terminus were obtained and subjected to a reaction with LiOH. There are two possible transformations under such conditions, one of which is ester hydrolys
Autor:
Sung Hyun Yoo, Jérémie Buratto, Arup Roy, Estelle Morvan, Morgane Pasco, Karolina Pulka-Ziach, Caterina M. Lombardo, Frédéric Rosu, Valérie Gabelica, Cameron D. Mackereth, Gavin W. Collie, Gilles Guichard
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, 2022, 144 (35), pp.15988-15998. ⟨10.1021/jacs.2c05234⟩
Journal of the American Chemical Society, 2022, 144 (35), pp.15988-15998. ⟨10.1021/jacs.2c05234⟩
International audience; Amphipathic water-soluble helices formed from synthetic peptides or foldamers are promising building blocks for the creation of self-assembled architectures with non-natural shapes and functions. While rationally designed arti
Publikováno v:
ChemPlusChem. 87(8)
Oligourea foldamers fold into 2.5-helices. Most of the known modifications of the backbone, such as NH or CO group substitutions or incorporations of non-canonical residues, do not change the conformational properties of the resulting oligourea oligo
Publikováno v:
The Journal of Physical Chemistry C. 124:17916-17923
We have designed and synthesized two α-helicomimetic foldamers composed of six urea residues with terminal ferrocene and cysteamine moieties. The direction of the net dipole moment in these two com...
Autor:
Olivier Hermine, Anna K. Puszko, Rachel Rignault-Bricard, Karolina Pulka-Ziach, Yves Lepelletier, Gérard Hopfgartner, Aleksandra Misicka, Piotr Sosnowski
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 72, p 72 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
Neuropilin-1 (NRP-1), the major co-receptor of vascular endothelial growth factor receptor-2 (VEGFR-2), may also independently act with VEGF-A165 to stimulate tumour growth and metastasis. Therefore, there is great interest in compounds that can bloc
Autor:
Cameron D. Mackereth, Gavin W. Collie, Sung Hyun Yoo, Frédéric Rosu, Caterina Lombardo, Valérie Gabelica, Gilles Guichard, Karolina Pulka-Ziach
Publikováno v:
Chemical Communications
Chemical Communications, Royal Society of Chemistry, 2021, ⟨10.1039/d1cc03604a⟩
Chemical Communications, 2021, ⟨10.1039/d1cc03604a⟩
Chemical Communications, Royal Society of Chemistry, 2021, ⟨10.1039/d1cc03604a⟩
Chemical Communications, 2021, ⟨10.1039/d1cc03604a⟩
We report here an oligourea foldamer able to self-assemble in aqueous conditions into helix bundles of multiple stoichiometries. Importantly, we report crystal structures of several of these stoichiometries, providing a series of high-resolutions sna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c3f61be3860bf6d8d65c1bc206f658
http://hdl.handle.net/20.500.12278/110219
http://hdl.handle.net/20.500.12278/110219
Publikováno v:
Electrochimica Acta. 403:139634
We have synthesized an oligourea foldamer containing seven urea residues, with a Cys-like residue introduced near the N-terminus of the helix. This enabled the immobilization of the molecules on gold electrode using gold-sulfur chemistry. Molecular l
Publikováno v:
The Journal of Physical Chemistry C. 123:1136-1141
α-Helicomimetic oligoureas are a class of compounds with a broad spectrum of applications, yet their use in materials science remains still unexplored. In this work, we have synthesized three oligomers composed of 8–12 residues and studied their e
Autor:
Olivier Hermine, Yves Lepelletier, Piotr Sosnowski, Karolina Pulka-Ziach, Aleksandra Misicka, Anna K. Puszko, Gérard Hopfgartner
Publikováno v:
Bioorganic & Medicinal Chemistry Letters, Vol. 29, No 17 (2019) pp. 2493-2497
NRP-1 is an important co-receptor of vascular endothelial growth factor receptor-2 (VEGFR-2). Many reports suggested that NRP-1 might also serve as a separate receptor for VEGF-A165 causing stimulation of tumour growth and metastasis. Therefore, comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f74744b51cadc712afec79f47de9a37
https://archive-ouverte.unige.ch/unige:142029
https://archive-ouverte.unige.ch/unige:142029
Autor:
Caterina Lombardo, Cameron D. Mackereth, Frédéric Rosu, Gilles Guichard, Gavin W. Collie, Valérie Gabelica, Karolina Pulka-Ziach
Publikováno v:
Journal of the American Chemical Society. 138:10522-10530
Non-natural synthetic oligomers that adopt well-defined secondary structures (i.e., foldamers) represent appealing components for the fabrication of bioinspired self-assembled architectures at the nanometer scale. Recently, peptidomimetic N,N'-linked