Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Karolina Lukasik"'
Bioinformatic analysis of endometrial miRNA expression profile at day 26–28 of pregnancy in the mare
Autor:
Agnieszka Sadowska, Tomasz Molcan, Anna Wójtowicz, Karolina Lukasik, Klaudia Pawlina-Tyszko, Artur Gurgul, Graca Ferreira-Dias, Dariusz J. Skarzynski, Anna Szóstek-Mioduchowska
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The establishment of the fetomaternal interface depends on precisely regulated communication between the conceptus and the uterine environment. Recent evidence suggests that microRNAs (miRNAs) may play an important role in embryo-maternal di
Externí odkaz:
https://doaj.org/article/8c691655be1e48ef82ec954668fa32b1
Autor:
Anna Wójtowicz, Tomasz Molcan, Karolina Lukasik, Ewelina Żebrowska, Klaudia Pawlina-Tyszko, Artur Gurgul, Tomasz Szmatoła, Monika Bugno-Poniewierska, Graca Ferreira-Dias, Dariusz J. Skarzynski, Anna Szóstek-Mioduchowska
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Mare endometrial fibrosis (endometrosis), is one of the main causes of equine infertility. Despite the high prevalence, both ethology, pathogenesis and the nature of its progression remain poorly understood. Recent studies have shown that mi
Externí odkaz:
https://doaj.org/article/d344cc26b28d436d93e9a5fd8359d543
Autor:
Barry O’Brien, John Reilly, Ken Coffey, Ana González-Suárez, Piotr Buchta, Piotr P. Buszman, Karolina Lukasik, Jason Tri, Martin van Zyl, Samuel Asirvatham
Publikováno v:
Bioengineering, Vol 11, Iss 1, p 18 (2023)
Epicardial pulsed field ablation (PFA) of ganglionated plexi (GPs) is being explored as a potential treatment for atrial fibrillation. Initial work using open-chest access with a monopolar ablation device has been completed. This study describes the
Externí odkaz:
https://doaj.org/article/543379ffeeb549828952df4e6e034a5e
Autor:
Ana Amaral, Carina Fernandes, Sofia Morazzo, Maria Rosa Rebordão, Anna Szóstek-Mioduchowska, Karolina Lukasik, Barbara Gawronska-Kozak, Luís Telo da Gama, Dariusz Jan Skarzynski, Graça Ferreira-Dias
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Although proteases found in neutrophil extracellular traps (NETs) have antimicrobial properties, they also stimulate collagen type 1 (COL1) production by the mare endometrium, contributing for the development of endometrosis. Cathepsin G (CAT), a pro
Externí odkaz:
https://doaj.org/article/4d22b3a9b19c4f7fa5c46bb10e42b61f
Autor:
Maria Montserrat Rivera del Alamo, Tiina Reilas, Karolina Lukasik, Antonio M. Galvão, Marc Yeste, Terttu Katila
Publikováno v:
Animals, Vol 11, Iss 12, p 3493 (2021)
Intrauterine devices (IUDs) are used in mares to suppress oestrous behaviour, but the underlying mechanism is yet to be elucidated. The presence of an embryo or an IUD prevents cyclooxygenase-2 (COX-2) and, subsequently, prostaglandin (PG) release an
Externí odkaz:
https://doaj.org/article/e860c11eda124f07aef4400577875f45
Autor:
Ana Amaral, Carina Fernandes, Anna Szóstek-Mioduchowska, Karolina Lukasik, Maria Rosa Rebordão, Pedro Pinto-Bravo, Dariusz Jan Skarzynski, Graça Ferreira-Dias
Publikováno v:
Life, Vol 11, Iss 10, p 1107 (2021)
Cathepsin G (CAT) is a protease released by neutrophils when forming neutrophil extracellular traps that was already associated with inducing type I collagen (COL1) in equine endometrium in vitro. Endometrosis is a fibrotic condition mainly character
Externí odkaz:
https://doaj.org/article/f8f5b65fe4f242d9889f44563c52fb17
Autor:
Maria Rosa Rebordão, Ana Amaral, Carina Fernandes, Elisabete Silva, Karolina Lukasik, Anna Szóstek-Mioduchowska, Pedro Pinto-Bravo, António Galvão, Dariusz J. Skarzynski, Graça Ferreira-Dias
Publikováno v:
Animals, Vol 11, Iss 9, p 2615 (2021)
Endometrosis, a fibrotic disease of mare endometrium, impairs uterine function. Prostaglandins (PG), despite modulating reproductive physiological functions, may also cause local pathological collagen deposition (fibrogenesis). We have previously sho
Externí odkaz:
https://doaj.org/article/e926bdc011fa4701a8d70d916273e2f9
Autor:
Ana Amaral, Carina Fernandes, Maria Rosa Rebordão, Anna Szóstek-Mioduchowska, Karolina Lukasik, Pedro Pinto-Bravo, Luís Telo da Gama, Dariusz Jan Skarzynski, Graça Ferreira-Dias
Publikováno v:
Animals, Vol 11, Iss 1, p 208 (2021)
Neutrophils can originate neutrophil extracellular traps (NETs). Myeloperoxidase (MPO) is a peroxidase found in NETs associated to equine endometrosis and can be inhibited by 4-aminobenzoic acid hydrazide (ABAH). Metallopeptidases (MMPs) participate
Externí odkaz:
https://doaj.org/article/28a4488a629a4be5aff34e9b03a6481d
Autor:
Ana Amaral, Carina Fernandes, Maria Rosa Rebordão, Anna Szóstek-Mioduchowska, Karolina Lukasik, Barbara Gawronska-Kozak, Luís Telo da Gama, Dariusz J. Skarzynski, Graça Ferreira-Dias
Publikováno v:
Animals, Vol 10, Iss 5, p 863 (2020)
Neutrophil extracellular traps (NETs) fight endometritis, and elastase (ELA), a protease found in NETs, might induce collagen type I (COL1) accumulation in equine endometrium. Metallopeptidases (MMPs) are involved in extracellular matrix balance. The
Externí odkaz:
https://doaj.org/article/139ec64c3d7e4822a002881c0649578b
Publikováno v:
Biology of reproduction. 107(6)
A molecular interaction between maternal endometrium and implanting conceptus can lead to activation of a variety of transcription factors that regulate expression of several genes necessary for the process of embryo implantation. While, signal trans