Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Karolina Kolodziejczyk"'
Publikováno v:
Neurobiology of Disease, Vol 86, Iss , Pp 62-74 (2016)
Huntington disease (HD), a neurodegenerative disorder caused by CAG repeat expansion in the gene encoding huntingtin, predominantly affects the striatum, especially the spiny projection neurons (SPN). The striatum receives excitatory input from corte
Externí odkaz:
https://doaj.org/article/87121f038eeb4597bd0f0b1ae75f8287
Autor:
Karolina Kolodziejczyk, Matthew P Parsons, Amber L Southwell, Michael R Hayden, Lynn A Raymond
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94562 (2014)
Huntington disease (HD) is a fatal neurodegenerative disorder caused by a CAG repeat expansion in the gene (HTT) encoding the huntingtin protein (HTT). This mutation leads to multiple cellular and synaptic alterations that are mimicked in many curren
Externí odkaz:
https://doaj.org/article/8df1b82f11df424ba898833b16e10adc
Publikováno v:
Nature
The myelin sheaths wrapped around axons by oligodendrocytes are crucial for brain function. In ischaemia myelin is damaged in a Ca(2+)-dependent manner, abolishing action potential propagation. This has been attributed to glutamate release activating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9c782058babea56f1f584ab72a35b9
http://europepmc.org/articles/PMC4733665
http://europepmc.org/articles/PMC4733665
Autor:
Lynn A. Raymond, Ken Mackie, Marja D. Sepers, Jeffrey M. LeDue, Karolina Kolodziejczyk, Amy I. Smith-Dijak
Huntington's disease (HD) is an inherited neurodegenerative disease affecting predominantly striatum and cortex that results in motor and cognitive disorders. Before a motor phenotype, animal models of HD show aberrant cortical-striatal glutamate sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6345c2d20487be298c5916f8598f92a0
https://europepmc.org/articles/PMC5777109/
https://europepmc.org/articles/PMC5777109/
Autor:
Anna Wade, Nicola B. Hamilton, Karolina Kolodziejczyk, Ragnhildur Thóra Káradóttir, David Attwell
Publikováno v:
Brain, 132 (6) pp. 1496-1508. (2009)
Brain
Brain
Elevations of the levels of N-acetyl-aspartyl-glutamate (NAAG) and N-acetyl-aspartate (NAA) are associated with myelin loss in the leucodystrophies Canavan's disease and Pelizaeus-Merzbacher-like disease. NAAG and NAA can activate and antagonize neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fbee1718d8c0a189ffaaaac351b560
https://doi.org/10.1093/brain/awp087
https://doi.org/10.1093/brain/awp087
Autor:
Lynn A. Raymond, Michael R. Hayden, Karolina Kolodziejczyk, Matthew P. Parsons, Amber L. Southwell
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94562 (2014)
PLoS ONE
PLoS ONE
Huntington disease (HD) is a fatal neurodegenerative disorder caused by a CAG repeat expansion in the gene (HTT) encoding the huntingtin protein (HTT). This mutation leads to multiple cellular and synaptic alterations that are mimicked in many curren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6569242b9ecc23a4a0e85454036c1e6f
http://europepmc.org/articles/PMC3984157?pdf=render
http://europepmc.org/articles/PMC3984157?pdf=render
Publikováno v:
F1000 Biology Reports; Vol 2
F1000 Biology Reports
Digital Repository Infrastructure Vision for European Research
MPG.PuRe
SESAM Publication Database-FP7 HEALTH
HEALTH FP7 Publications Database
Europe PubMed Central
F1000 Biology Reports
Digital Repository Infrastructure Vision for European Research
MPG.PuRe
SESAM Publication Database-FP7 HEALTH
HEALTH FP7 Publications Database
Europe PubMed Central
The function of glutamate receptors on oligodendrocytes and their precursor cells is poorly understood, with their only clear action being to damage these cells in pathological conditions. Here we review recent studies of glutamate signalling to olig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162c90fd6819a6100ce4d0e0e7fa60b1
http://europepmc.org/articles/PMC2990618
http://europepmc.org/articles/PMC2990618