Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Karolina Dębowska"'
Autor:
Karolina Pierzchała, Marlena Pięta, Monika Rola, Małgorzata Świerczyńska, Angelika Artelska, Karolina Dębowska, Radosław Podsiadły, Jakub Pięta, Jacek Zielonka, Adam Sikora, Andrzej Marcinek, Radosław Michalski
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract MPO-derived oxidants including HOCl contribute to tissue damage and the initiation and propagation of inflammatory diseases. The search for small molecule inhibitors of myeloperoxidase, as molecular tools and potential drugs, requires the ap
Externí odkaz:
https://doaj.org/article/0d0c54d8360f4776869e515cc662ed47
Publikováno v:
Advances in Dermatology and Allergology, Vol 40, Iss 1, Pp 176-177 (2022)
Externí odkaz:
https://doaj.org/article/5b47aa782b684d70b8a41e5039e3c1f4
Autor:
Adam Sikora, Jacek Zielonka, Karolina Dębowska, Radosław Michalski, Renata Smulik-Izydorczyk, Jakub Pięta, Radosław Podsiadły, Angelika Artelska, Karolina Pierzchała, Balaraman Kalyanaraman
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Boronate-based molecular probes are emerging as one of the most effective tools for detection and quantitation of peroxynitrite and hydroperoxides. This review discusses the chemical reactivity of boronate compounds in the context of their use for de
Externí odkaz:
https://doaj.org/article/5ea21736d5f045d893e2d5e8b209a297
Autor:
Aleksandra Grzelakowska, Julia Modrzejewska, Jolanta Kolińska, Marcin Szala, Monika Zielonka, Karolina Dębowska, Małgorzata Zakłos-Szyda, Adam Sikora, Jacek Zielonka, Radosław Podsiadły
Publikováno v:
Free Radical Biology and Medicine. 179:34-46
Peroxynitrite (ONOO
Autor:
Mikołaj Łanocha, Karolina Dębowska, Aleksandra Frątczak, Karina Polak, Beata Sylwia Bergler-Czop
Publikováno v:
Forum Dermatologicum.
Autor:
Aleksandra Grzelakowska, Jacek Zielonka, Julia Modrzejewska, Adam Sikora, Karolina Dębowska, Monika Zielonka, Marcin Szala, Radosław Podsiadły
Publikováno v:
Free Radical Biology and Medicine. 169:24-35
A new naphthalene-based boronate probe, NAB-BE, for the fluorescence-based detection of inflammatory oxidants, including peroxynitrite, hypochlorous acid, and hydrogen peroxide, is reported. The chemical reactivity and fluorescence properties of the
Autor:
Radosław Michalski, Jan Adamus, Karolina Dębowska, Michał Rostkowski, Renata Smulik-Izydorczyk, Adam Sikora
Publikováno v:
Cell Biochemistry and Biophysics
HNO (nitroxyl, IUPAC name azanone) is an electrophilic reactive nitrogen species of growing pharmacological and biological significance. Here, we present data on the pH-dependent kinetics of azanone reactions with the low molecular thiols glutathione
Autor:
Angelika Artelska, Jacek Zielonka, Adam Sikora, Radosław Michalski, Jakub Pięta, Radosław Podsiadły, Balaraman Kalyanaraman, Karolina Pierzchała, Renata Smulik-Izydorczyk, Karolina Dębowska
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Frontiers in Chemistry
Frontiers in Chemistry
Boronate-based molecular probes are emerging as one of the most effective tools for detection and quantitation of peroxynitrite and hydroperoxides. This review discusses the chemical reactivity of boronate compounds in the context of their use for de
Autor:
Adam Sikora, Jan Adamus, Renata Smulik, Andrzej Marcinek, Dawid Debski, Balaraman Kalyanaraman, Karolina Dębowska, Jacek Zielonka, Małgorzata Jakubowska, Bartosz Michałowski
Publikováno v:
Free Radical Biology and Medicine. 95:323-332
Amplex® Red (10-acetyl-3,7-dihydroxyphenoxazine) is a fluorogenic probe widely used to detect and quantify hydrogen peroxide in biological systems. Detection of hydrogen peroxide is based on peroxidase-catalyzed oxidation of Amplex® Red to resorufi
Autor:
Andrzej Marcinek, Bartosz Michałowski, Renata Smulik, Karolina Dębowska, Dawid Debski, Małgorzata Jakubowska, Radosław Michalski, Tomasz Wojcik, Jan Adamus, Łukasz Piotrowski, Agnieszka Dybala-Defratyka, Anna Selmi, Stefan Chlopicki, Adam Sikora
Publikováno v:
Chemical Research in Toxicology. 29:735-746
Boronate probes have emerged recently as a versatile tool for the detection of reactive oxygen and nitrogen species. Here, we present the characterization of a fluorescein-based monoboronate probe, a 4-(pinacol boronate)benzyl derivative of fluoresce