Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Karolina Łuczkowska"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Lenalidomide (LEN) is widely used immunomodulatory drug (IMiD). Nonetheless, despite its efficacy, over time patients become resistant to LEN and relapse. Due to high clinical relevance, drug resistance in MM is being thoroughly investigated
Externí odkaz:
https://doaj.org/article/f958be6c6c40429f880fdd8fc219c068
Publikováno v:
Nutrients, Vol 16, Iss 1, p 142 (2023)
Multiple myeloma (MM) is a plasma cell malignancy that, despite recent advances in therapy, continues to pose a major challenge to hematologists. Currently, different classes of drugs are applied to treat MM, among others, proteasome inhibitors, immu
Externí odkaz:
https://doaj.org/article/d961633308924d4096a9b16c45dcc553
Autor:
Ewa Pius-Sadowska, Piotr Kulig, Anna Niedźwiedź, Bartłomiej Baumert, Karolina Łuczkowska, Dorota Rogińska, Anna Sobuś, Zofia Ulańczyk, Miłosz Kawa, Edyta Paczkowska, Miłosz Parczewski, Anna Machalińska, Bogusław Machaliński
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17003 (2023)
The pathophysiology of the severe course of COVID-19 is multifactorial and not entirely elucidated. However, it is well known that the hyperinflammatory response and cytokine storm are paramount events leading to further complications. In this paper,
Externí odkaz:
https://doaj.org/article/7c2f3e1b8e7944b8b6ed2d0fb493287b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16780 (2023)
Multiple myeloma (MM) is a plasma cell malignancy that accounts for 1% of all cancers and is the second-most-common hematological neoplasm. Bortezomib (BTZ) is a proteasome inhibitor widely implemented in the treatment of MM alone or in combination w
Externí odkaz:
https://doaj.org/article/fe880b10995a44c2a6abafb019f0e13c
Autor:
Maria Dąbkowska, Zofia Ulańczyk, Karolina Łuczkowska, Dorota Rogińska, Anna Sobuś, Monika Wasilewska, Maria Olszewska, Katarzyna Jakubowska, Bogusław Machaliński
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-22 (2021)
Abstract Background The rational chemical design of nanoparticles can be readily controlled and optimized by quantitatively studying protein adsorption at variously charged polymer carriers, determining their fate in biological fluids. We manufacture
Externí odkaz:
https://doaj.org/article/9dafd7729185444484559e65cb58558a
Autor:
Jan Bińkowski, Olga Taryma-Leśniak, Karolina Łuczkowska, Anna Niedzwiedź, Kacper Lechowicz, Dominik Strapagiel, Justyna Jarczak, Veronica Davalos, Aurora Pujol, Manel Esteller, Katarzyna Kotfis, Bogusław Machaliński, Miłosz Parczewski, Tomasz K. Wojdacz
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113396- (2022)
Recent studies have shown that methylation changes identified in blood cells of COVID-19 patients have a potential to be used as biomarkers of SARS-CoV-2 infection outcomes. However, different studies have reported different subsets of epigenetic les
Externí odkaz:
https://doaj.org/article/e8ce83065b3445a99e8c3c45371ad3bd
Autor:
Karolina Rogulska, Iwona Wojciechowska-Koszko, Barbara Krasnodębska-Szponder, Paweł Kwiatkowski, Paulina Roszkowska, Barbara Dołęgowska, Karolina Łuczkowska, Bogusław Machaliński, Danuta Kosik-Bogacka
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 11925 (2023)
Intestinal trefoil factor 3 (TFF3) is a protein secreted by many cell types, and its serum and urine levels vary in patients with kidney disease. Therefore, the present study aimed to determine the diagnostic value of TFF3 in allogeneic kidney transp
Externí odkaz:
https://doaj.org/article/4194c3eebbb34b4198d1d70d0452dd7e
Autor:
Karolina Łuczkowska, Katarzyna Ewa Sokolowska, Olga Taryma-Lesniak, Krzysztof Pastuszak, Anna Supernat, Jonas Bybjerg-Grauholm, Lise Lotte Hansen, Edyta Paczkowska, Tomasz K. Wojdacz, Bogusław Machaliński
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The anticancer activity of bortezomib (BTZ) has been increasingly studied in a number of indications and promising results for the use of this treatment have been shown in neuroblastoma. As BTZ treatment is usually administered in cycles, th
Externí odkaz:
https://doaj.org/article/f1af3d190e0e46aab864a91cdf1eba2b
Autor:
Maria Dąbkowska, Karolina Łuczkowska, Dorota Rogińska, Anna Sobuś, Monika Wasilewska, Zofia Ulańczyk, Bogusław Machaliński
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Brain-derived neurotrophic factor (BDNF) is essential for the development and function of human neurons, therefore it is a promising target for neurodegenerative disorders treatment. Here, we studied BDNF-based electrostatic complex with den
Externí odkaz:
https://doaj.org/article/d8d8f58d164c4b1bbcc4f442267cf554
Autor:
Miłosz P. Kawa, Anna Sobuś, Ewa Pius-Sadowska, Karolina Łuczkowska, Dorota Rogińska, Szymon Wnęk, Edyta Paczkowska, Mieczysław Walczak, Anhelli Syrenicz, Bogusław Machaliński
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15794 (2022)
Abnormalities in hematological parameters of peripheral blood have been noted in patients with endogenous Cushing’s Syndrome (CS) in the corticotropin (ACTH)-dependent and ACTH-independent forms. Nevertheless, the exact mechanism of glucocorticoids
Externí odkaz:
https://doaj.org/article/e64186bb2c5c47e3b3e17fd263418a31