Výsledky vyhledávání - "Karolin Zoll"

S-2-PENTYL-4-PENTYNOIC HYDROXAMIC ACID AND ITS METABOLITE S-2-PENTYL-4-PENTYNOIC ACID IN THE NMRI-EXENCEPHALY-MOUSE MODEL: PHARMACOKINETIC PROFILES, TERATOGENIC EFFECTS, AND HISTONE DEACETYLASE INHIBITION ABILITIES OF FURTHER VALPROIC ACID HYDROXAMATES AND AMIDES

Autor: Karolin Zoll, Daniel Eikel, Heinz Nau, Katrin Hoffmann, Alfonso Lampen

Publikováno v: Drug Metabolism and Disposition. 34:612-620

Structure-activity relationship studies of valproic acid (VPA) derivatives have revealed a quantitative correlation between histone deacetylase (HDAC) inhibition and induction of neural tube defects (NTDs) in the NMRI-exencephaly-mouse model, but thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be071b25556352c94f6a045b2a55039b
https://doi.org/10.1124/dmd.105.008078

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