Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Karolin Walter"'
Autor:
Sandra Valle, Sonia Alcalá, Laura Martin-Hijano, Pablo Cabezas-Sáinz, Diego Navarro, Edurne Ramos Muñoz, Lourdes Yuste, Kanishka Tiwary, Karolin Walter, Laura Ruiz-Cañas, Marta Alonso-Nocelo, Juan A. Rubiolo, Emilio González-Arnay, Christopher Heeschen, Laura Garcia-Bermejo, Patrick C. Hermann, Laura Sánchez, Patricia Sancho, Miguel Ángel Fernández-Moreno, Bruno Sainz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Long-term cultures of pancreatic cancer stem cells (PaCSCs) are difficult to obtain. Here, the authors present a 2D culture method, based on the use of galactose, to establish cell cultures from pancreatic ductal adenocarcinoma xenotransplants enrich
Externí odkaz:
https://doaj.org/article/318cab6a23144c398f4c1aba8ef19747
Autor:
Karolin Walter, Eva Rodriguez-Aznar, Monica S. Ventura Ferreira, Pierre-Olivier Frappart, Tabea Dittrich, Kanishka Tiwary, Sabine Meessen, Laura Lerma, Nora Daiss, Lucas-Alexander Schulte, Zeynab Najafova, Frank Arnold, Valentyn Usachov, Ninel Azoitei, Mert Erkan, Andre Lechel, Tim H. Brümmendorf, Thomas Seufferlein, Alexander Kleger, Enrique Tabarés, Cagatay Günes, Steven A. Johnsen, Fabian Beier, Bruno Sainz, Patrick C. Hermann
Publikováno v:
Cancers, Vol 13, Iss 13, p 3145 (2021)
To assess the role of telomerase activity and telomere length in pancreatic CSCs we used different CSC enrichment methods (CD133, ALDH, sphere formation) in primary patient-derived pancreatic cancer cells. We show that CSCs have higher telomerase act
Externí odkaz:
https://doaj.org/article/7536e3dbc92b4f4ca5bc955bbe9e0702
Autor:
Karolin Walter, Kanishka Tiwary, Marija Trajkovic-Arsic, Ana Hidalgo-Sastre, Laura Dierichs, Sven T. Liffers, Jiangning Gu, Johann Gout, Lucas-Alexander Schulte, Jan Münch, Thomas Seufferlein, Bruno Sainz, Jens T. Siveke, Eva Rodriguez-Aznar, Patrick C. Hermann
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Pancreatic ductal adenocarcinoma (PDAC) remains a devastating disease with a very poor prognosis. At the same time, its incidence is on the rise, and PDAC is expected to become the second leading cause of cancer-related death by 2030. Despite extensi
Externí odkaz:
https://doaj.org/article/ad1215332ec0444484f7cbd7da9ccd50
Autor:
Lukas Perkhofer, Karolin Walter, Ivan G. Costa, Maria C. Romero Carrasco, Tim Eiseler, Susanne Hafner, Felicitas Genze, Martin Zenke, Wendy Bergmann, Anett Illing, Meike Hohwieler, Ralf Köhntop, Qiong Lin, Karl-Heinz Holzmann, Thomas Seufferlein, Martin Wagner, Stefan Liebau, Patrick C. Hermann, Alexander Kleger, Martin Müller
Publikováno v:
Stem Cell Research, Vol 17, Iss 2, Pp 367-378 (2016)
Cell fate decisions and pluripotency, but also malignancy depend on networks of key transcriptional regulators. The T-box transcription factor TBX3 has been implicated in the regulation of embryonic stem cell self-renewal and cardiogenesis. We have r
Externí odkaz:
https://doaj.org/article/9019fa26caa448eea278bc5735935149
Autor:
Alexander Kleger, Pierre-Olivier Frappart, Thomas Seufferlein, Peter Möller, Hans A. Kestler, Sebastian Wiese, Volker Rasche, Konstantin M.J. Sparrer, Ewa K. Kaminska, Axel Fürstberger, Li Hao, Ninel Azoitei, Thomas J. Ettrich, André Lechel, Caterina Prelli Bozzo, Jeanette Scheible, Karolin Walter, Lukas Perkhofer, Elodie Roger, Stephanie E. Weissinger, Heike Wiese, Johann Gout, Frank Arnold
Pancreatic ductal adenocarcinoma (PDAC) still presents with a dismal prognosis despite intense research. Better understanding of cellular homeostasis could identify druggable targets to improve therapy. Here we propose RAD50-interacting protein 1 (RI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a81c0c354220e7de74d24c2ff7f54301
https://doi.org/10.1158/0008-5472.c.6513184.v1
https://doi.org/10.1158/0008-5472.c.6513184.v1
Autor:
Alexander Kleger, Pierre-Olivier Frappart, Thomas Seufferlein, Peter Möller, Hans A. Kestler, Sebastian Wiese, Volker Rasche, Konstantin M.J. Sparrer, Ewa K. Kaminska, Axel Fürstberger, Li Hao, Ninel Azoitei, Thomas J. Ettrich, André Lechel, Caterina Prelli Bozzo, Jeanette Scheible, Karolin Walter, Lukas Perkhofer, Elodie Roger, Stephanie E. Weissinger, Heike Wiese, Johann Gout, Frank Arnold
Contains a more detailed method section as well as all additional supplementary figures S1 to S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3053d93096593f057df6b3f3dc3cf5
https://doi.org/10.1158/0008-5472.22428880.v1
https://doi.org/10.1158/0008-5472.22428880.v1
Autor:
Andreas Riegger, Kurt Kremer, Yu Tokura, Bettina Stöckle, Nora Daiss, Tanja Weil, Debashish Mukherji, Patrick C. Hermann, Chaojian Chen, Karolin Walter, Onofrio Zirafi, Frank Kirchhoff, Jan Münch, David Y. W. Ng
Publikováno v:
ACS macro letters. 6(3)
Peptide–polymer conjugates have been regarded as primary stronghold in biohybrid nanomedicine, which has seen extensive development due to its intrinsic property to provide complementary functions of both the peptide material and the synthetic poly
Autor:
Emilio González-Arnay, Diego Navarro, Patrick C. Hermann, Marta Alonso-Nocelo, Laura García-Bermejo, Lourdes Yuste, Sonia Alcalá, Laura Martin-Hijano, Edurne Ramos Muñoz, Laura Ruiz-Cañas, Laura Sánchez, Miguel Ángel Fernández-Moreno, Christopher Heeschen, Patricia Sancho, Bruno Sainz, Juan A. Rubiolo, Karolin Walter, Pablo Cabezas-Sainz, Sandra Valle, Kanishka Tiwary
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
© The Author(s) 2020
Pancreatic ductal adenocarcinoma (PDAC), the fourth leading cause of cancer death, has a 5-year survival rate of approximately 7–9%. The ineffectiveness of anti-PDAC therapies is believed to be due to the existence of a s
Pancreatic ductal adenocarcinoma (PDAC), the fourth leading cause of cancer death, has a 5-year survival rate of approximately 7–9%. The ineffectiveness of anti-PDAC therapies is believed to be due to the existence of a s
Autor:
Kanishka Tiwary, Mirja Harms, Bastian Beitzinger, Roman Schmid, Syeda Inaas, Karolin Walter, Alexander Kleger, Mika Lindén, Thomas Seufferlein, Jan Münch, Patrick Christian Hermann
Publikováno v:
Cancer Research. 83:B034-B034
Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer characterized by late diagnosis, lack of early symptoms and extensive metastasis. One of the foremost reasons for such startling statistics is the presence of a subpopulation of highly plasti
Autor:
Kanishka Tiwary, Anton Lahusen, Syeda Inaas, Stefanie Hauff, Karolin Walter, Alexander Kleger, Thomas Seufferlein, Bruno Sainz, Patrick Christian Hermann
Publikováno v:
Cancer Research. 83:B035-B035
Pancreatic cancer is a fatal disease and is one of the most aggressive and metastatic malignancies worldwide. The dissemination of tumor cells is the prerequisite of metastases and correlates with a loss of epithelial differentiation and the acquisit