Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Karolin Guldevall"'
Autor:
Joachim Koch, Sheena Pinto, Susanne Wingert, Jens Pahl, Chiara Zambarda, Karolin Guldevall, Christian Breunig, Damien Toullec, Jacopo Fontana, Björn Önfelt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/dde28aa9a42d4f86ae8c60c460702adf
Autor:
Dhifaf Sarhan, Ludwig Brandt, Martin Felices, Karolin Guldevall, Todd Lenvik, Peter Hinderlie, Julie Curtsinger, Erica Warlick, Stephen R. Spellman, Bruce R. Blazar, Daniel J. Weisdorf, Sarah Cooley, Daniel A. Vallera, Björn Önfelt, Jeffrey S. Miller
Publikováno v:
Blood Advances, Vol 2, Iss 12, Pp 1459-1469 (2018)
Abstract: Myelodysplastic syndrome (MDS) is a clonal heterogeneous stem cell disorder driven by multiple genetic and epigenetic alterations resulting in ineffective hematopoiesis. MDS has a high frequency of immune suppressors, including myeloid-deri
Externí odkaz:
https://doaj.org/article/0305f116a4114bdda91c6b8ab45c6574
Autor:
Karolin Guldevall, Bruno Vanherberghen, Thomas Frisk, Johan Hurtig, Athanasia E Christakou, Otto Manneberg, Sara Lindström, Helene Andersson-Svahn, Martin Wiklund, Björn Önfelt
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15453 (2010)
New markers are constantly emerging that identify smaller and smaller subpopulations of immune cells. However, there is a growing awareness that even within very small populations, there is a marked functional heterogeneity and that measurements at t
Externí odkaz:
https://doaj.org/article/ee687e7da27b4bffbf0099dfddfc84ba
Autor:
Chiara Zambarda, Karolin Guldevall, Damien Toullec, Susanne Wingert, Christian Breunig, Sheena Pinto, Jacopo Fontana, Joachim Koch, Björn Önfelt
Publikováno v:
Cancer Research. 83:2950-2950
Antibody-Dependent Cellular Cytotoxicity (ADCC) is a powerful mechanism of Natural Killer (NK) cells to kill antibody-opsonized target cells. However, ADCC mediated by conventional antibodies has its limitations in killing of tumor cells commonly bei
Autor:
Niklas Sandström, Ludwig Brandt, Patrick A. Sandoz, Chiara Zambarda, Karolin Guldevall, Malte Schulz-Ruhtenberg, Bernd Rösener, Robin A. Krüger, Björn Önfelt
Publikováno v:
Lab on a chip. 22(11)
Miniaturization of cell culture substrates enables controlled analysis of living cells in confined micro-scale environments. This is particularly suitable for imaging individual cells over time, as they can be monitored without escaping the imaging f
Autor:
Chiara Zambarda, Karolin Guldevall, Christian Breunig, Damien Toullec, Jacopo Fontana, Sheena Pinto, Jens Pahl, Susanne Wingert, Joachim Koch, Björn Önfelt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundThe use of bispecific natural killer (NK) cell engagers has emerged as a successful strategy for immune cell activation and killing of tumor cells through antibody-dependent cellular cytotoxicity (ADCC). Among these, tetravalent, bispecific
Autor:
Erica D. Warlick, Peter Hinderlie, Todd Lenvik, Jeffrey S. Miller, Dhifaf Sarhan, Stephen R. Spellman, Karolin Guldevall, Ludwig Brandt, Bruce R. Blazar, Björn Önfelt, Martin Felices, Sarah Cooley, Daniel J. Weisdorf, Daniel A. Vallera, Julie M. Curtsinger
Publikováno v:
Blood Advances. 2:1459-1469
Myelodysplastic syndrome (MDS) is a clonal heterogeneous stem cell disorder driven by multiple genetic and epigenetic alterations resulting in ineffective hematopoiesis. MDS has a high frequency of immune suppressors, including myeloid-derived suppre
Autor:
Katherine, Walwyn-Brown, Karolin, Guldevall, Mezida, Saeed, Daniela, Pende, Björn, Önfelt, Andrew S, MacDonald, Daniel M, Davis
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 201(7)
Cross-talk between NK cells and dendritic cells (DCs) is important in Th1 immune responses, including antitumor immunity and responses to infections. DCs also play a crucial role in polarizing Th2 immunity, but the impact of NK cell-DC interactions i
Autor:
Bjorn Onfelt, Karolin Guldevall, Ludwig Brandt, Karl Olofsson, Valentina Carannante, Niklas Sandström, Martin Wiklund
Publikováno v:
The Journal of Immunology. 202:131.29-131.29
Driven by a wave of new and improved methods for single cell analysis, e.g. flow cytometry, mass cytometry and single cell sequencing, it is increasingly recognized that there is a vast heterogeneity between individual cells within traditional cell c
Autor:
Bruno, Vanherberghen, Thomas, Frisk, Elin, Forslund, Per E, Olofsson, Karolin, Guldevall, Björn, Önfelt
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1441
NK cell heterogeneity has primarily been studied either on the population level, measuring average responses, or on the single cell level by flow cytometry, providing static snapshots. These approaches have certain drawbacks, not enabling dynamic obs