Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Karoliina Stefanius"'
Autor:
Karoliina Stefanius, Kelly Servage, Marcela de Souza Santos, Hillery Fields Gray, Jason E Toombs, Suneeta Chimalapati, Min S Kim, Venkat S Malladi, Rolf Brekken, Kim Orth
Publikováno v:
eLife, Vol 8 (2019)
Cancer evolves through a multistep process that occurs by the temporal accumulation of genetic mutations. Tumor-derived exosomes are emerging contributors to tumorigenesis. To understand how exosomes might contribute to cell transformation, we utiliz
Externí odkaz:
https://doaj.org/article/d1922c4d232445f49f2061be196cfa8a
Autor:
Amanda K. Casey, Hillery F. Gray, Suneeta Chimalapati, Genaro Hernandez, Andrew T. Moehlman, Nathan Stewart, Hazel A. Fields, Burak Gulen, Kelly A. Servage, Karoliina Stefanius, Aubrie Blevins, Bret M. Evers, Helmut Krämer, Kim Orth
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The proper balance of synthesis, folding, modification, and degradation of proteins, also known as protein homeostasis, is vital to cellular health and function. The unfolded protein response (UPR) is activated when the mechanisms maintaining protein
Publikováno v:
Current Opinion in Genetics & Development. 66:83-92
Exosomes are secreted small extracellular vesicles (EVs) packaged with diverse biological cargo. They mediate complex intercellular communications among cells in maintenance of normal physiology or to trigger profound disease progression. Increasing
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Extracellular vesicles secreted from tumor cells are functional vehicles capable of contributing to intercellular communication and metastasis. A growing number of studies have focused on elucidating the role that tumor-derived extracellular vesicles
Autor:
Rolf A. Brekken, Jason E. Toombs, Min S. Kim, Kim Orth, Karoliina Stefanius, Marcela de Souza Santos, Venkat S. Malladi, Suneeta Chimalapati, Hillery Fields Gray, Kelly A. Servage
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
Cancer evolves through a multistep process that occurs by the temporal accumulation of genetic mutations. Tumor-derived exosomes are emerging contributors to tumorigenesis. To understand how exosomes might contribute to cell transformation, we utiliz
Autor:
Venkat S. Malladi, Marcela de Souza Santos, Hillery Fields Gray, Suneeta Chimalapati, Kelly A. Servage, Jason E. Toombs, Min S. Kim, Karoliina Stefanius, Rolf A. Brekken, Kim Orth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e30c9f72e977db311c9e6f19f13a1159
https://doi.org/10.7554/elife.40226.032
https://doi.org/10.7554/elife.40226.032
Autor:
Hillery Fields Gray, Kelly A. Servage, Jason E. Toombs, Karoliina Stefanius, Suneeta Chimalapati, Rolf A. Brekken, Marcela de Souza Santos, Min S. Kim, Kim Orth
Cancer evolves through a multistep process that occurs by the temporal accumulation of genetic mutations mediated by intracellular and extracellular cues. We observe that exosomes isolated from pancreatic cancer cells, but not normal pancreatic cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f41a903cbc22c0f81ee9aa03283e9f
Autor:
Anne Tuomisto, Laura Ylitalo, Päivi Sirniö, Tiina Kantola, Rami Kuivila, Markus J. Mäkinen, Karoliina Stefanius, Tuomo J. Karttunen
Publikováno v:
Histopathology. 58:679-692
Stefanius K, Ylitalo L, Tuomisto A, Kuivila R, Kantola T, Sirnio P, Karttunen T J & Makinen M J (2011) Histopathology58, 679–692 Frequent mutations of KRAS in addition to BRAF in colorectal serrated adenocarcinoma Aims: To define the occurrence of
Autor:
Tiina Kantola, Lauri A. Aaltonen, Markus J. Mäkinen, Anne Tuomisto, Pia Vahteristo, Karoliina Stefanius, Tuomo J. Karttunen, Auli Karhu
Publikováno v:
Virchows Archiv. 458:213-219
Colorectal serrated adenocarcinoma forms about 15-20% of colorectal carcinomas. We have previously shown that downregulation of PTCH1 is distinctive for this type of colorectal cancer. In several other tumor types, somatic inactivating PTCH1 mutation
Autor:
Dinesh Rakheja, Robert E. Hammer, Ivan Pedrosa, Shanshan Wang, James Brugarolas, Xian Jin Xie, Renée M. McKay, Thomas L. Carroll, Yi Feng Gu, Nicholas C. Wolff, Karoliina Stefanius, Anwesha Dey, Alana Christie, Payal Kapur
Why different species are predisposed to different tumor spectra is not well understood. In particular, whether the physical location of tumor suppressor genes relative to one another influences tumor predisposition is unknown. Renal cancer presents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a797c98b1de70c0b7a80a3427e93021
https://europepmc.org/articles/PMC4246264/
https://europepmc.org/articles/PMC4246264/