Zobrazeno 1 - 10 of 40 pro vyhledávání: '"Karolien Claes"'
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Infliximab Concentration Thresholds During Induction Therapy Are Associated With Short-term Mucosal Healing in Patients With Ulcerative Colitis
Autor: Sophie Tops, Marc Ferrante, Paul Rutgeerts, Thomas Billiet, Niels Vande Casteele, Konstantinos Papamichael, Ann Gils, Gert Van Assche, Severine Vermeire, Karolien Claes, Thomas Van Stappen
Publikováno v: Clinical Gastroenterology and Hepatology. 14:543-549
Background & Aims Mucosal healing is an independent predictor of sustained clinical remission in patients with ulcerative colitis (UC) treated with infliximab. We investigated whether infliximab concentrations during induction therapy are associated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54431b86aeb149b5896ad1f9113abaed
https://doi.org/10.1016/j.cgh.2015.11.014
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2
A decrease of the butyrate-producing speciesRoseburia hominisandFaecalibacterium prausnitziidefines dysbiosis in patients with ulcerative colitis
Autor: Marc Ferrante, Venessa Eeckhaut, Vera Ballet, Marie Joossens, Paul Rutgeerts, João Sabino, Severine Vermeire, Jan Verhaegen, Filip Van Immerseel, Ingrid Arijs, Kathleen Machiels, Vicky De Preter, Karolien Claes, Kristin Verbeke
Publikováno v: Gut. 63:1275-1283
OBJECTIVE: Bacteria play an important role in the onset and perpetuation of intestinal inflammation in inflammatory bowel disease (IBD). Unlike in Crohn's disease (CD), in which dysbiosis has been better characterised, in ulcerative colitis (UC), onl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0c2e26796969867928283d7d54e435
https://doi.org/10.1136/gutjnl-2013-304833
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3
The role of vascular endothelial growth factor (VEGF) in inflammatory bowel disease
Autor: Marc Ferrante, Liesbet Henckaerts, Robert Vlietinck, Marie J. Pierik, Marie Joossens, Karolien Claes, Nele Van Schuerbeek, Gert Van Assche, Severine Vermeire, Paul Rutgeerts
Publikováno v: Inflammatory Bowel Diseases. 12:870-878
Background: Vascular endothelial growth factor (VEGF) is a candidate susceptibility gene to inflammatory bowel disease (IBD), both from a functional as well as genetic perspective. Moreover, serum VEGF (sVEGF) levels are increased in IBD and correlat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0814c2db3c6b0a3c2d4a1ee026e230
https://doi.org/10.1097/01.mib.0000235095.01608.10
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5
Influence of Trough Serum Levels and Immunogenicity on Long-term Outcome of Adalimumab Therapy in Crohn's Disease
Autor: Gilles Paintaud, Tamara Coopman, Maja Noman, Paul Rutgeerts, Marc Ferrante, Severine Vermeire, Danielle Degenne, Nele Van Schuerbeek, Charlotte Magdelaine-Beuzelin, Konstantinos Karmiris, Gert Van Assche, Karolien Claes
Publikováno v: Gastroenterology
Gastroenterology, WB Saunders, 2009, 137 (5), pp.1628-1640
International audience; BACKGROUND & AIMS: Adalimumab is an efficacious therapy for active Crohn's disease, but long-term data are scarce. We conducted an observational study to assess the long-term clinical benefit of adalimumab in patients who fail
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019e481aa0a0315971c8ed0885f73505
https://hal.science/hal-00616825
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6
286 Drug Concentrations and Antibodies to Infliximab Are Inferior to the Impact of Disease Burden in Primary Non-Response to Infliximab in Crohn's Disease Patients
Autor: Vera Ballet, Karolien Claes, Marc Ferrante, Severine Vermeire, Fred Princen, Thomas Billiet, Isabelle Cleynen, Gert A. Van Assche, Sharat Singh
Publikováno v: Gastroenterology. 148:S-62
Introduction The mechanisms behind primary non-response (PNR) to infliximab (IFX) in IBD are still incompletely understood. The role of IFX trough levels (TL) and early antibody formation (ATI) during the induction phase (0-2-6 weeks) are contradicti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::64066d03ebedc7b7b0269877a069870e
https://doi.org/10.1016/s0016-5085(15)30215-8
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9
Mo1746 Human-Leukocyte Antigen Type Is Associated With Duration on Infliximab Therapy in Patients With Antibodies to Infliximab
Autor: Thomas Billiet, Isabelle Cleynen, Sharat Singh, Marc Ferrante, Severine Vermeire, Karolien Claes, Fred Princen, Ann Gils, Gert A. Van Assche, Niels Vande Casteele, Thomas Van Stappen, Vera Ballet
Publikováno v: Gastroenterology. 148:S-701
Inc.). Patient and therapy factors and the number of allele carriers for the different DRB1 alleles were compared between cases and controls. Stepwise logistic regression was performed to identify independent predictors of ATI formation. Results At I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6ac704b10cd471086c5978a7755e93e
https://doi.org/10.1016/s0016-5085(15)32376-3
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