Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Karola Vorauer-Uhl"'
Autor:
Dominik Damm, Ehsan Suleiman, Hannah Theobald, Jannik T. Wagner, Mirjam Batzoni, Bianca Ahlfeld (née Kohlhauser), Bernd Walkenfort, Jens-Christian Albrecht, Jidnyasa Ingale, Lifei Yang, Mike Hasenberg, Richard T. Wyatt, Karola Vorauer-Uhl, Klaus Überla, Vladimir Temchura
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1385 (2022)
Functionalization of experimental HIV-1 virus-like particle vaccines with heterologous T helper epitopes (T helper VLPs) can modulate the humoral immune response via intrastructural help (ISH). Current advances in the conjugation of native-like HIV-1
Externí odkaz:
https://doaj.org/article/d6bcf5265dc047d3a53880797af39283
Autor:
Ehsan Suleiman, Dominik Damm, Mirjam Batzoni, Vladimir Temchura, Andreas Wagner, Klaus Überla, Karola Vorauer-Uhl
Publikováno v:
Pharmaceutics, Vol 11, Iss 11, p 619 (2019)
Since the first use of liposomes as carriers for antigens, much work has been done to elucidate the mechanisms involved in the encapsulation of vaccine-relevant biomolecules. However, only a few studies have specifically investigated the encapsulatio
Externí odkaz:
https://doaj.org/article/51607de900f64ee6800d94a705cae2fa
Publikováno v:
Biotechnology progressREFERENCES. 38(5)
Glycation on lysine side chains of recombinant monoclonal antibodies (mAb) is a well-known phenomenon in manufacturing processes of biopharmaceuticals that potentially alter the efficacy of the therapeutic protein. In the present study, we report kin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7813020206f4e25117c39ee4d47e2b17
https://pubmed.ncbi.nlm.nih.gov/35429153
https://pubmed.ncbi.nlm.nih.gov/35429153
Glycation on lysine side chains of recombinant monoclonal antibodies (mAb) is a well known phenomenon in manufacturing processes of biopharmaceuticals that potentially alter the efficacy of the therapeutic protein. Previously, we reported a method to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dd1b29af97feba666a2a59263435ff8
https://doi.org/10.22541/au.163506359.97922307/v1
https://doi.org/10.22541/au.163506359.97922307/v1
Autor:
Karola Vorauer-Uhl, Gerald Striedner, Bernhard Sissolak, Gabriele Lhota, Wolfgang Sommeregger
Publikováno v:
Biotechnology Progress
Post‐translational, nonenzymatic glycation of monoclonal antibodies (mAbs) in the presence of reducing sugars (in bioprocesses) is a widely known phenomenon, which affects protein heterogeneity and potentially has an impact on quality, safety, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1c1f5e3075b44823c85045e0d9a965
https://pubmed.ncbi.nlm.nih.gov/33428326
https://pubmed.ncbi.nlm.nih.gov/33428326
Autor:
Alexandra Castilho, Laura Neumann, Pia Gattinger, Richard Strasser, Karola Vorauer-Uhl, Thomas Sterovsky, Friedrich Altmann, Herta Steinkellner
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54836 (2013)
Hyperglycosylated proteins are more stable, show increased serum half-life and less sensitivity to proteolysis compared to non-sialylated forms. This applies particularly to recombinant human erythropoietin (rhEPO). Recent progress in N-glycoengineer
Externí odkaz:
https://doaj.org/article/b5f06cfea02040d2973c071052b72e7a
Autor:
Ehsan, Suleiman, Julia, Mayer, Elisabeth, Lehner, Bianca, Kohlhauser, Alexandra, Katholnig, Mirjam, Batzoni, Dominik, Damm, Vladimir, Temchura, Andreas, Wagner, Klaus, Überla, Karola, Vorauer-Uhl
Publikováno v:
Pharmaceutics
The display of native-like human immunodeficiency virus type 1 envelope (HIV-1 Env) trimers on liposomes has gained wide attention over the last few years. Currently, available methods have enabled the preparation of Env-liposome conjugates of unprec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e04f35809690c7f19c585bd98b10ebf9
https://pubmed.ncbi.nlm.nih.gov/33081278
https://pubmed.ncbi.nlm.nih.gov/33081278
Autor:
Jakob Wallner, Krisztina Koczka, Karola Vorauer-Uhl, Lisa Nika, Reingard Grabherr, Dieter Palmberger
Publikováno v:
Protein Expression and Purification. 136:27-38
Biomarkers of cancer are often glycosylated membrane receptor proteins present on the cellular surface. In order to develop new antibodies for cancer diagnostics or treatment, it is a main pre-requisite that these target proteins are available in a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ea0af297e31dd7b4514f7a3aba6c52
https://doi.org/10.1016/j.pep.2017.06.005
https://doi.org/10.1016/j.pep.2017.06.005