Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Karola Marczinek"'
Autor:
Karen Uhlmann, Karola Marczinek, Siegfried Vogel, Constanze Zeller, Klaus Rohde, Janusz Szymas, Peter W. Laird, Gundula Thiel, Peter Nürnberg
Publikováno v:
International Journal of Cancer. 106:52-59
Gliomas are tumors of the central nervous system with a wide spectrum of different tumor types. They range from pilocytic astrocytoma, with a generally good prognosis, to the extremely aggressive malignant glioblastoma. In addition to these 2 types o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d549ca1a7c7afb6edfce62c5ad7f630
https://doi.org/10.1002/ijc.11175
https://doi.org/10.1002/ijc.11175
Publikováno v:
Electrophoresis. 20:1748-1755
Two-dimensional DNA fingerprinting (2-D fingerprinting) is a sensitive tool for genomic difference analysis between tumor DNA and constitutive DNA of glioma patients. Numerous differences were found even in low-grade gliomas. They can be interpreted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28275f97e92007258a3c285fd8f8bc52
https://doi.org/10.1002/(sici)1522-2683(19990101)20:8<1748::aid-elps1748>3.0.co
https://doi.org/10.1002/(sici)1522-2683(19990101)20:8<1748::aid-elps1748>3.0.co
Autor:
Jochen Hampe, Gundula Thiel, Wilio J. F. de Leeuw, Peter Nürnberg, Regina Neumann, Akio Sugiyama, Karola Marczinek, Karin Lehmann
Publikováno v:
Electrophoresis. 18:1586-1591
Two-dimensional (2-D) DNA fingerprinting was used to investigate genomic changes in human low-grade gliomas of different subtypes. DNA variations were identified in the 2-D hybridization patterns as spot losses or gains. Computer-aided matching of sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5effded7647bb1076648c2da7534580c
https://doi.org/10.1002/elps.1150180917
https://doi.org/10.1002/elps.1150180917
Publikováno v:
Electrophoresis. 17:659-666
Two-dimensional (2-D) DNA fingerprinting is a promising technique for multilocus analysis of eukaryotic genomes. It has been successfully applied to the detection of DNA variation in tumors, to linkage analyses and to genomic comparisons of inbred mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28c7e92d61a59842c4af83603385b78
https://doi.org/10.1002/elps.1150170406
https://doi.org/10.1002/elps.1150170406
Publikováno v:
Electrophoresis. 16:1715-1725
The detection of DNA variation in cancers is an important step in elucidating the mechanism of tumorigenesis. Using the strategy of multipoint genome analysis we detected many differences between glioma-derived and constitutional DNA by customary DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1efc2b445282b68757ade153c466d00
https://doi.org/10.1002/elps.11501601284
https://doi.org/10.1002/elps.11501601284
Publikováno v:
DNA Profiling and DNA Fingerprinting ISBN: 9783764360184
The basic principle of the two-dimensional (2D) separation of DNA fragments was developed by Fischer and Lehrman in 1979 [1], who applied this method to the detection of variation in the Escherichia coli genome. The introduction of blotting and hybri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e62c54f789af631ee65ddce029bb67b
https://doi.org/10.1007/978-3-0348-7582-0_13
https://doi.org/10.1007/978-3-0348-7582-0_13
Autor:
Gundula Thiel, Karola Marczinek, Jochen Hampe, Ralf Mrowka, Karen Uhlmann, Ingrid Barth, Peter Nürnberg, Siegfried Vogel
Publikováno v:
Glia. 23(2)
Cytogenetic and molecular analyses such as allelotyping studies have revealed several genetic changes typical for human glial neoplasms. However, most studies to date have involved malignant gliomas and thus are likely to reflect late events of tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1a822cd4f9ca8b1563f73248d8cf17
https://pubmed.ncbi.nlm.nih.gov/9600381
https://pubmed.ncbi.nlm.nih.gov/9600381
Publikováno v:
Electrophoresis. 18(15)
Two-dimensional (2-D) DNA fingerprinting is a technique that allows for parallel genome analysis through the simultaneous detection of up to 500 mini- or microsatellite loci on a 2-D gel. Separation is performed according to size and melting temperat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd64effc9a051dc48dbefb10ad87bd22
https://pubmed.ncbi.nlm.nih.gov/9504825
https://pubmed.ncbi.nlm.nih.gov/9504825
Publikováno v:
Archives of neurology. 54(4)
Background: The familial spastic paraplegias (FSPs) are hereditary neurodegenerative disorders with an unknown pathogenesis. Pure and complicated forms are currently differentiated on clinical grounds. To date, no linkage studies in complicated FSP h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cae128ef49476f15ee83df2d3a4843
https://pubmed.ncbi.nlm.nih.gov/9109738
https://pubmed.ncbi.nlm.nih.gov/9109738
Publikováno v:
Electrophoresis; Jun1999, Vol. 20 Issue 8, p1748-1755, 8p