Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Karol R. Francisco"'
Autor:
Lawrence J. Liu, Bobby Lucero, Cindy Manriquez-Rodriguez, Karol R. Francisco, Thaiz R. Teixeira, Darius J. Yohannan, Carlo Ballatore, Samuel A. Myers, Anthony J. O’Donoghue, Conor R. Caffrey
Publikováno v:
ACS Omega, Vol 9, Iss 32, Pp 34829-34840 (2024)
Externí odkaz:
https://doaj.org/article/216d446cd15c4572865786ea4be7e282
Autor:
Obaid Hayat, Nazif Ullah, Muhammad Sirajuddin, Miriam A. Giardini, Jennifer V. Nguyen, Karol R. Francisco, Lawrence J. Liu, Yujie Uli Sun, Svetlana Maurya, Dominic McGrosso, David J. Gonzalez, Conor R. Caffrey, Anjan Debnath, Jair L. Siqueira-Neto
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1424 (2022)
Metals have been used in medicine since ancient times for the treatment of different ailments with various elements such as iron, gold and arsenic. Metal complexes have also been reported to show antibiotic and antiparasitic activity. In this context
Externí odkaz:
https://doaj.org/article/3a11b00416ca4f92923dce5b3db08fed
Autor:
Hanna F. Roenfanz, Thomas J. Paniak, Cameron B. Berlin, Van Tran, Karol R. Francisco, Pierrik Lassalas, Anisha Devas, Olivia Landes, Avalon Rosenberger, Madeline E. Rotella, Carlo Ballatore, Marisa C. Kozlowski
Publikováno v:
Chemistry – A European Journal.
Autor:
Gautam Mitra, Jonathan Z. Low, Sujun Wei, Karol R. Francisco, Michael Deffner, Carmen Herrmann, Luis M. Campos, Elke Scheer
Publikováno v:
Nano Letters. 22:5773-5779
We report transport measurements on tunable single-molecule junctions of the organic perchlorotrityl radical molecule, contacted with gold electrodes at low temperature. The current-voltage characteristics of a subset of junctions shows zero-bias ano
Autor:
Masebe Kanyanta, Chilufya Lengwe, Dickson Mambwe, Karol R. Francisco, Lawrence J. Liu, Yujie Uli Sun, Dilini K. Amarasinghe, Conor R. Caffrey, Peter Mubanga Cheuka
Publikováno v:
Bioorg Med Chem Lett
For the Schistosoma mansoni flatworm pathogen, we report a structure–activity relationship of 25 derivatives of the N-phenylbenzamide compound, 1 (MMV687807), a Medicines for Malaria Venture compound for which bioactivity was originally identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da819e8d998a6b8f54e3652c6cef882
https://europepmc.org/articles/PMC10072318/
https://europepmc.org/articles/PMC10072318/
Autor:
Karol R. Francisco, Ludovica Monti, Wenqian Yang, Hayoung Park, Lawrence J. Liu, Kaitlyn Watkins, Dilini K. Amarasinghe, Marianna Nalli, Carlos Roberto Polaquini, Luis O. Regasini, Antônio Eduardo Miller Crotti, Romano Silvestri, Lizandra Guidi Magalhães, Conor R. Caffrey
Publikováno v:
Bioorg Med Chem Lett
Trypanosoma brucei is a protozoan parasite that causes Human African Trypanosomiasis (HAT), a neglected tropical disease (NTD) that is endemic in 36 countries in sub-Saharan Africa. Only a handful drugs are available for treatment, and these have lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0670ede9525c7d5e85ecca79c141b48b
https://europepmc.org/articles/PMC10072319/
https://europepmc.org/articles/PMC10072319/
Autor:
Thibault Alle, Carmine Varricchio, Yuemang Yao, Bobby Lucero, Goodwell Nzou, Stefania Demuro, Megan Muench, Khoa D. Vuong, Killian Oukoloff, Anne-Sophie Cornec, Karol R. Francisco, Conor R. Caffrey, Virginia M.-Y. Lee, Amos B. Smith, Andrea Brancale, Kurt R. Brunden, Carlo Ballatore
Publikováno v:
Journal of medicinal chemistry, vol 66, iss 1
Microtubule (MT)-stabilizing 1,2,4-triazolo[1,5-a]pyrimidines (TPDs) hold promise as candidate therapeutics for Alzheimer's disease (AD) and other neurodegenerative conditions. However, depending on the choice of substituents around the TPD core, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec72b970204417d9dd0cef026d13404
https://escholarship.org/uc/item/7zv2q880
https://escholarship.org/uc/item/7zv2q880
Autor:
Thibault, Alle, Carmine, Varricchio, Yuemang, Yao, Bobby, Lucero, Goodwell, Nzou, Stefania, Demuro, Megan, Muench, Khoa D, Vuong, Killian, Oukoloff, Anne-Sophie, Cornec, Karol R, Francisco, Conor R, Caffrey, Virginia M-Y, Lee, Amos B, Smith, Andrea, Brancale, Kurt R, Brunden, Carlo, Ballatore
Publikováno v:
Journal of medicinal chemistry.
Microtubule (MT)-stabilizing 1,2,4-triazolo[1,5
Autor:
Yingying Zhang, Marilyn R. Gunner, Junjun Mao, Stefan M. Kast, Teresa Danielle Bergazin, Karol R. Francisco, Carlo Ballatore, Nicolas Tielker, David L. Mobley
Publikováno v:
Journal of Computer-Aided Molecular Design
The Statistical Assessment of Modeling of Proteins and Ligands (SAMPL) challenges focuses the computational modeling community on areas in need of improvement for rational drug design. The SAMPL7 physical property challenge dealt with prediction of o
Autor:
Miguel Alejandro Lopez-Ramirez, Brendan Gongol, John Y.-J. Shyy, Karol R. Francisco, Chelsea H J Choi, Mark K. Haynes, Hao Sun, Carlo Ballatore, Larry A. Sklar, Sara McCurdy, Preston Hale, Wenqing Li, Killian Oukoloff, Alexandre R. Gingras, Matthew Bautista
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 5, Pp 334-355 (2021)
FASEB bioAdvances, vol 3, iss 5
FASEB BioAdvances
FASEB bioAdvances, vol 3, iss 5
FASEB BioAdvances
The transmembrane protein heart of glass1 (HEG1) directly binds to and recruits Krev interaction trapped protein 1 (KRIT1) to endothelial junctions to form the HEG1–KRIT1 protein complex that establishes and maintains junctional integrity. Genetic