Affinity Chromatography: An Enabling Technology for Large-Scale Bioprocessing

Autor: Frank Riske, Karol M Łącki

Publikováno v: Biotechnology journal. 15(1)

Affinity chromatography (AC) has been used in large-scale bioprocessing for almost 40 years and is considered the preferred method for primary capture in downstream processing of various types of biopharmaceuticals. The objective of this mini-review

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a003e89265afab58cdbdbe45754838f5
https://pubmed.ncbi.nlm.nih.gov/31544994

Overview of Alternative Separation Methods in Relation to Process Challenges

Autor: Günter Jagschies, James M. Van Alstine, Karol M. Łącki

This chapter provides an overview of alternative separation methods in order to help the reader decide if such methods are of interest, how they compare with other methods, and what particular approaches may suit specific process challenges. Alternat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6579d674d53962d1d707408405f6ce88
https://doi.org/10.1016/b978-0-08-100623-8.00010-4

Alternative Separation Methods: Crystallization and Aqueous Polymer Two-Phase Extraction

Autor: Karol M. Łącki, Günter Jagschies, James M. Van Alstine

As with many other alternative separations methods, crystallization and aqueous polymer two-phase extraction (ATPE) have been well-studied academically and are amenable to predictive and process modeling. Their solution nature allows them to be optim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cacb8f9baad1b8479097bfe1c1ede2ee
https://doi.org/10.1016/b978-0-08-100623-8.00012-8

Contributors

Autor: John W. Armando, E. Morrey Atkinson, Peter Bernhardt, Torbjörn S. Blank, Yvonne A. Brady, Eggert Brekkan, Andrea Buchacher, Karolina Busson, Maire H. Caparon, Enrique N. Carredano, Jeffrey R. Carter, Andreas Castan, Shuang Chen, Kenneth P. Clapp, Scott A. Cook, John T. Cundy, John M. Curling, Åke Danielsson, Kjell O. Eriksson, Alain Fairbank, Suzanne S. Farid, Simon Fischer, Kine A.-K. Frej, Parrish M. Galliher, Klaus Gebauer, Glen S. Giese, Alan Gilbert, Anna Grönberg, Albrecht Gröner, Robert S. Gronke, Martin Hall, Kim R. Hejnaes, Rachel S. Hendricks, Rolf A. Hjorth, Geoff Hodge, Matt H. Hutchinson, Günter Jagschies, Michael J. Jenkins, Mikael I. Johansson, John Joseph, Oliver Kaltenbrunner, Gautam Kapoor, Tomas M. Karlsson, Brian D. Kelley, Annika Kleinjans, Jashwant Kumar, Karol M. Łącki, Philip Lester, Jakob Liderfelt, Xin Xin Lin, Eva K. Lindskog, Mats Lundgren, Ratish Mangalath-Illam, Trevor J. Marshall, Joseph P. Martin, Krunal K. Mehta, Brian Montgomery, Daniel Nelson, Roger Nordberg, Dana A. Olson, Martin Östling, John P. Pieracci, David J. Pollard, Alain Pralong, Hari Pujar, Joost P. Quaadgras, Tom C. Ransohoff, Anurag S. Rathore, Craig Robinson, Jonathan Royce, Michael A. Rubacha, Henrik Sandegren, Andreas Schaubmar, Patrick Schulz, Sumit K. Singh, Stephen E. Sobacke, Sriram Srinivasan, Matthew J. Stork, Bruce S. Tangarone, Jorg Thommes, Matthew J. Traylor, Johan Tschöp, James M. Van Alstine, Johnson Varghese, Ganesh Vedantham, Thomas von Hirschheydt, William B. Wellborn, Till Wenger, Susanne Westin, David G. Westman, Matthew Westoby, William G. Whitford, Ambrose J. Williams, John M. Woodgate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ab37a02755962071e60b3fe89a67442
https://doi.org/10.1016/b978-0-08-100623-8.09990-4

Downstream Process Design, Scale-Up Principles, and Process Modeling

Autor: John Joseph, Karol M. Łącki, Kjell O. Eriksson

The chapter provides the reader with the basic understanding of process design and discusses few concepts important for consideration during this stage of the product lifecycle. The main focus of the chapter is on the downstream purification part of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0abb4f2a535bfef03bb7af7cb270fb41
https://doi.org/10.1016/b978-0-08-100623-8.00032-3