Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Karol Jopek"'
Autor:
Edyta Kawka, Rebecca Herzog, Marcin Ruciński, Agnieszka Malińska, Markus Unterwurzacher, Juan Manuel Sacnun, Anja Wagner, Katarzyna Kowalska, Karol Jopek, Agata Kucz-Chrostowska, Klaus Kratochwill, Janusz Witowski
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Transforming growth factor β (TGF-β) is implicated in both mesothelial-to-mesenchymal transition (MMT) and cellular senescence of human peritoneal mesothelial cells (HPMCs). We previously showed that senescent HPMCs could spontaneously acq
Externí odkaz:
https://doaj.org/article/2cb8718db5424f74bfee025654002816
Autor:
Anna Olechnowicz, Małgorzata Blatkiewicz, Karol Jopek, Mark Isalan, Michal Mielcarek, Marcin Rucinski
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2176 (2024)
Huntington’s disease (HD) is a neurodegenerative disorder that affects mainly the central nervous system (CNS) by inducing progressive deterioration in both its structure and function. In recent years, there has been growing interest in the impact
Externí odkaz:
https://doaj.org/article/a73acf3214b84602a45df81c2fe797de
Autor:
Małgorzata Blatkiewicz, Marta Szyszka, Anna Olechnowicz, Kacper Kamiński, Karol Jopek, Hanna Komarowska, Marianna Tyczewska, Anna Klimont, Tomasz Wierzbicki, Marek Karczewski, Marek Ruchała, Marcin Rucinski
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1038 (2024)
The discovery of mitochondria-derived peptides (MDPs) has provided a new perspective on mitochondrial function. MDPs encoded by mitochondrial DNA (mtDNA) can act as hormone-like peptides, influencing cell survival and proliferation. Among these pepti
Externí odkaz:
https://doaj.org/article/9d20389871fd45efbbb22fe6089da8bc
Autor:
Karol Jopek, Marianna Tyczewska, Marta Szyszka, Małgorzata Blatkiewicz, Maria Jopek, Ludwik K. Malendowicz, Marcin Ruciński
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13412 (2023)
Urotensin 2 (Uts2) is a biologically active peptide involved in the regulation of a variety of physiological and pathophysiological processes. In both the human and rat adrenal gland, the expressions of the Uts2 gene and its receptor (Uts2r) have bee
Externí odkaz:
https://doaj.org/article/9432c834b6af4c73a2dac2f8ffd875c0
Autor:
Rut Bryl, Mariusz J. Nawrocki, Karol Jopek, Mariusz Kaczmarek, Dorota Bukowska, Paweł Antosik, Paul Mozdziak, Maciej Zabel, Piotr Dzięgiel, Bartosz Kempisty
Publikováno v:
Genes, Vol 14, Iss 6, p 1223 (2023)
Heart failure remains a major cause of death worldwide. There is a need to establish new management options as current treatment is frequently suboptimal. Clinical approaches based on autologous stem cell transplant is potentially a good alternative.
Externí odkaz:
https://doaj.org/article/9c28ab7b3d7f4b0fbf2c2b042ef065ff
Autor:
Marianna Tyczewska, Patrycja Sujka-Kordowska, Marta Szyszka, Karol Jopek, Małgorzata Blatkiewicz, Ludwik K. Malendowicz, Marcin Rucinski
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9159 (2023)
The homeostasis of the adrenal gland plays a decisive role in its proper functioning, both in non-stressful conditions and under the influence of various types of stress. This consists of interactions between all types of cells that make up the organ
Externí odkaz:
https://doaj.org/article/032dea5fc6104c4487ef1a20981841eb
Autor:
Ewelina Stelcer, Katarzyna Kulcenty, Marcin Rucinski, Marta Kruszyna-Mochalska, Agnieszka Skrobala, Agnieszka Sobecka, Karol Jopek, Wiktoria Maria Suchorska
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Human induced pluripotent stem cells (hiPSCs) can be differentiated into chondrocyte-like cells. However, implantation of these cells is not without risk given that those transplanted cells may one day undergo ionizing radiation (IR) in pati
Externí odkaz:
https://doaj.org/article/f91a3d76fc2949ebac10e37da13f30e3
Autor:
Mariusz J. Nawrocki, Karol Jopek, Mariusz Kaczmarek, Maciej Zdun, Paul Mozdziak, Marek Jemielity, Bartłomiej Perek, Dorota Bukowska, Bartosz Kempisty
Publikováno v:
Genes, Vol 13, Iss 7, p 1205 (2022)
Numerous cardiovascular diseases (CVD) eventually lead to severe myocardial dysfunction, which is the most common cause of death worldwide. A better understanding of underlying molecular mechanisms of cardiovascular pathologies seems to be crucial to
Externí odkaz:
https://doaj.org/article/518c2385bd8b4257891432e2b9a4f761
Autor:
Piotr Stasiak, Dominika Kaźmierczak, Karol Jopek, Michał Nowicki, Marcin Rucinski, Radosław Januchowski
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5846 (2022)
Epithelial ovarian cancer has the highest mortality among all gynecological malignancies. The main reasons for high mortality are late diagnosis and development of resistance to chemotherapy. Resistance to chemotherapeutic drugs can result from alter
Externí odkaz:
https://doaj.org/article/12e8bb35b2cf4cd9b67d422546fc27b0
Autor:
Igor Piotrowski, Katarzyna Kulcenty, Wiktoria Suchorska, Marcin Rucinski, Karol Jopek, Marta Kruszyna-Mochalska, Agnieszka Skrobala, Piotr Romanski, Adam Ryczkowski, Dorota Borowicz, Natalia Matuszak, Julian Malicki
Publikováno v:
Cancers, Vol 14, Iss 11, p 2712 (2022)
Hypo-fractionated stereotactic body radiation therapy (SBRT) is an effective treatment for prostate cancer (PCa). Although many studies have investigated the effects of SBRT on the prostate and adjacent organs, little is known about the effects furth
Externí odkaz:
https://doaj.org/article/c0cf53a7a4b544de91d40e092c56078d