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Autor:
Karol Horvath, Martin Brodszki, Hans Wallberg, Horst Wähling, Håkan Malmgren, Mikael Pelcman, Birthe Bäckström, Torbjörn Larsson, Johan Wennerberg
Publikováno v:
Organic Process Research & Development. 15:1027-1032
2′,3′-Dideoxy-3′-fluoro-5-O-[(S)-(+)-2-(l-valyloxy)-propionyl] guanosine (lagociclovir valactate) is a prodrug of 3′-fluoro-2′,3′-dideoxyguanosine with high oral bioavailability in humans and potent activity against hepatitis B virus (HBV