Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Karol Dowjat"'
Autor:
Urszula Wojda, Tatyana Adayev, Tomasz Gabryelewicz, Anna Barczak, Katarzyna Brzozowska, Karol Dowjat, Yu-Wen Hwang
Publikováno v:
Journal of Alzheimer's Disease
Background DYRK1A is implicated in mental retardation and Alzheimer's disease (AD) dementia of Down syndrome (DS) individuals. The protein is associated with cytoskeleton and altered expression has been shown to impair the cytoskeletal network via do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72dac3dc43541c3b207a820b8cbbee0
https://doi.org/10.3233/jad-190475
https://doi.org/10.3233/jad-190475
Publikováno v:
Alzheimer's & Dementia. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a933351d62f5d120a17098027ef20f3
https://doi.org/10.1016/j.jalz.2015.08.056
https://doi.org/10.1016/j.jalz.2015.08.056
Publikováno v:
Carcinogenesis. 16:1753-1759
7,8-Dihydro-8-oxo-2'-deoxyguanosine (8-oxo-dG) was measured as an indicator of nickel-induced oxidative base damage in the presence of H 2 O 2 . Heterochromatic proteins isolated from Chinese hamster liver cells enhanced the formation of 8-oxo-dG ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f7a3cfac5a3dd7fe9fd18062caf708
https://doi.org/10.1093/carcin/16.8.1753
https://doi.org/10.1093/carcin/16.8.1753
The triplication of the DYRK1A gene encoding proline-directed serine/threonine kinase and located in the critical region of Down syndrome (DS) has been implicated in cognitive deficits and intellectual disability of individuals with DS. We investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54745c46bd45943cff73eaef849253fa
https://europepmc.org/articles/PMC3511598/
https://europepmc.org/articles/PMC3511598/
Autor:
Yu Wen Hwang, Tatyana Adayev, Barry Reisberg, Janusz Frackowiak, Jerzy Wegiel, Thomas Wisniewski, Karol Dowjat, Mo Chou Chen-Hwang, Wayne Silverman, Mony deLeon, Izabela Kuchna, Krzysztof Nowicki
Publikováno v:
Brain research. 1010(1-2)
The minibrain kinase (Mnb/Dyrk1A) gene is localized in the Down syndrome (DS) critical region of chromosome 21. This gene encodes a proline-directed serine/threonine protein kinase (minibrain kinase-Mnb/Dyrk1A), which is required for the proliferatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548d93110eba54a40df1ef786ec47665
https://pubmed.ncbi.nlm.nih.gov/15126119
https://pubmed.ncbi.nlm.nih.gov/15126119
Anti-(U1)snRNP autoantibodies inhibit homologous pairing activity of the human recombination complex
Autor:
Karol Dowjat
Publikováno v:
DNA and cell biology. 16(7)
The co-purification of the U1snRNP particle with a high-molecular-weight human homologous pairing activity has been observed consistently. Using human autoimmune sera directed against various snRNPs, it has been found that autoantibody binding to ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df56bcf5ab19e214657b763bc6242cf
https://pubmed.ncbi.nlm.nih.gov/9260925
https://pubmed.ncbi.nlm.nih.gov/9260925
Publikováno v:
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 9(4)
Copper/zinc (Cu/ZnSOD) and manganese (MnSOD) superoxide dismutases which catalyze the dismutation of toxic superoxide anion, O inf2 sup− , to O2 and H2O2, play a major role in protecting cells from toxicity of oxidative stress. However, cells overe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33105141f4cdfb7c60d3c6aedbfd6fe
https://pubmed.ncbi.nlm.nih.gov/8837454
https://pubmed.ncbi.nlm.nih.gov/8837454
Publikováno v:
Biometals. 9
Using a procedure aimed at isolation of genes that are inactivated during nickel-induced carcinogenesis in Chinese hamster cells, a homolog of genes encoding human and mouse heme containing peroxidases has been cloned. Northern blot analysis of norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c87614127ce14cf203566338ef634f4
https://doi.org/10.1007/bf00144620
https://doi.org/10.1007/bf00144620
Autor:
I. Kuchna, Michal Tarnawski, Jerzy Wegiel, Karol Dowjat, H. M. Wisniewski, J Kulczycki, Eulalia Badmajew, Thomas Wisniewski
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 57:512
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4913e51d602616ef2e3d1422dcaab5e8
https://doi.org/10.1097/00005072-199805000-00190
https://doi.org/10.1097/00005072-199805000-00190
Autor:
Karol Dowjat
Publikováno v:
European Journal of Cancer and Clinical Oncology. 21:233-242
An attempt was made to establish permanent in vitro cultures of L1210 leukemia cells under close chromosome control. The investigations involved three independent adaptations. The karyotype was analyzed by the G-banding method. Chromosome analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2f9c974629dec59a7410234d9062e9
https://doi.org/10.1016/0277-5379(85)90178-6
https://doi.org/10.1016/0277-5379(85)90178-6