Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Karolína Šeborová"'
Autor:
Karolina Seborova, Viktor Hlavac, Petr Holy, Sunniva S. Bjørklund, Thomas Fleischer, Lukas Rob, Martin Hruda, Jiri Bouda, Marcela Mrhalova, Mohammad Moufaq Khatar Al Obeed Allah, Pavel Vodicka, Ondrej Fiala, Pavel Soucek, Vessela N. Kristensen, Ludmila Vodickova, Radka Vaclavikova
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Epithelial ovarian carcinoma (EOC) is known for high mortality due to diagnosis at advanced stages and frequent therapy resistance. Previous findings suggested that the DNA repair system is involved in the therapeutic response of cancer patients and
Externí odkaz:
https://doaj.org/article/4d3c2d1b733a4311bfac5bc44475ebba
Autor:
Karolina Seborova, Kamila Koucka, Alzbeta Spalenkova, Petr Holy, Marie Ehrlichova, Tomas Sychra, Lei Chen, Hersh Bendale, Iwao Ojima, Cristian Sandoval-Acuña, Jaroslav Truksa, Pavel Soucek, Radka Vaclavikova
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Taxanes are widely used in the treatment of ovarian carcinomas. One of the main problems with conventional taxanes is the risk of development of multidrug resistance. New-generation synthetic experimental taxoids (Stony Brook Taxanes; SB-T) have show
Externí odkaz:
https://doaj.org/article/40f498fcbaef46a1889e236533885e53
Autor:
Petr Holý, Veronika Brynychová, Karolína Šeborová, Vojtěch Haničinec, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Pavel Souček
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2074-2089 (2023)
Oxysterols, oxidized derivatives of cholesterol, act in breast cancer (BC) as selective estrogen receptor modulators and affect cholesterol homeostasis, drug transport, nuclear and cell receptors, and other signaling proteins. Using data from three h
Externí odkaz:
https://doaj.org/article/dc346fd6f49f495581f9e427e684f5cc
Autor:
Jitka Viktorová, Simona Dobiasová, Kateřina Řehořová, David Biedermann, Kristýna Káňová, Karolína Šeborová, Radka Václavíková, Kateřina Valentová, Tomáš Ruml, Vladimír Křen, Tomáš Macek
Publikováno v:
Antioxidants, Vol 8, Iss 8, p 303 (2019)
Silychristin A is the second most abundant compound of silymarin. Silymarin complex was previously described as an antioxidant with multidrug resistance modulation activity. Here, the results of a classical biochemical antioxidant assay (ORAC) were c
Externí odkaz:
https://doaj.org/article/076e3a2b920347f3a338d9b2dfaca536
Autor:
Petr Daniel, Kamila Balušíková, Radka Václavíková, Karolína Šeborová, Šárka Ransdorfová, Marie Valeriánová, Longfei Wei, Michael Jelínek, Tereza Tlapáková, Thomas Fleischer, Vessela N. Kristensen, Pavel Souček, Iwao Ojima, Jan Kovář
Publikováno v:
Genes
Volume 14
Issue 2
Pages: 296
Volume 14
Issue 2
Pages: 296
A limited number of studies are devoted to regulating TRIP6 expression in cancer. Hence, we aimed to unveil the regulation of TRIP6 expression in MCF-7 breast cancer cells (with high TRIP6 expression) and taxane-resistant MCF-7 sublines (manifesting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7176c7efb40a442186947b2a5e687d43
Autor:
Martin Hruda, Viktor Hlaváč, Petr Holý, Karolína Šeborová, Radka Václavíková, Marcela Mrhalová, Petr Černaj, Jiří Bouda, Pavel Souček, Lukáš Rob
Publikováno v:
Ovarian cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::761acaf8a38aec34dd9cbc2a694c6963
https://doi.org/10.1136/ijgc-2022-esgo.578
https://doi.org/10.1136/ijgc-2022-esgo.578
Autor:
Tomas Sychra, Alzbeta Spalenkova, Stepan Balatka, Radka Vaclavikova, Karolina Seborova, Marie Ehrlichova, Jaroslav Truksa, Cristian Sandoval-Acuña, Vlasta Nemcova, Arpad Szabo, Kamila Koci, Tereza Tesarova, Lei Chen, Iwao Ojima, Martin Oliverius, Pavel Soucek
Publikováno v:
iScience, Vol 27, Iss 2, Pp 109044- (2024)
Summary: Pancreatic cancer is a severe malignancy with increasing incidence and high mortality due to late diagnosis and low sensitivity to treatments. Search for the most appropriate drugs and therapeutic regimens is the most promising way to improv
Externí odkaz:
https://doaj.org/article/a032fb8b23884f2993b71832d334ba03
Autor:
Karolina Seborova, Radka Vaclavikova, Pavel Soucek, Katerina Elsnerova, Alena Bartakova, Petr Cernaj, Jiri Bouda, Lukas Rob, Martin Hruda, Pavel Dvorak
Publikováno v:
Cancer Medicine, Vol 8, Iss 2, Pp 606-616 (2019)
Abstract Introduction Ovarian cancer (OC) represents a serious disease with high mortality and lack of efficient predictive and prognostic biomarkers. ATP‐binding cassette (ABC) proteins constitute a large family dedicated to active transmembrane t
Externí odkaz:
https://doaj.org/article/4226b8e44ddc49938d5292df14cafd04