Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Karni Schlessinger"'
Autor:
Huizhong Xiong, Antonio Maraver, Jo-Ann Latkowski, Tanya Henderson, Karni Schlessinger, Yi Ding, Jie Shen, Carlos E Tadokoro, Juan J Lafaille
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84841 (2013)
Notch signaling is essential for the development of T cell progenitors through the interaction of NOTCH1 receptor on their surface with the ligand, Delta-like 4 (DLL4), which is expressed by the thymic epithelial cells. Notch signaling is quickly shu
Externí odkaz:
https://doaj.org/article/f690b377ab564b5e8c168d4f1cb5a1a4
Autor:
David E. Levy, Karni Schlessinger
Signal transducer and activator of transcription 3 (STAT3) has been indirectly implicated in numerous fundamental cellular processes, including proliferation, survival, and differentiation. We provide genetic evidence from studies of STAT3-null cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8528e58ad80f75bd6b9533f397f23eb7
https://doi.org/10.1158/0008-5472.c.6493839
https://doi.org/10.1158/0008-5472.c.6493839
Autor:
David E. Levy, Karni Schlessinger
Supplementary Figure 2 from Malignant Transformation but not Normal Cell Growth Depends on Signal Transducer and Activator of Transcription 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a2816da81526edf951f31240c39feb
https://doi.org/10.1158/0008-5472.22363689.v1
https://doi.org/10.1158/0008-5472.22363689.v1
Autor:
David E. Levy, Karni Schlessinger
Supplementary Figure 1 from Malignant Transformation but not Normal Cell Growth Depends on Signal Transducer and Activator of Transcription 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ca6c78e22dbe08a6a46004092fa0d5
https://doi.org/10.1158/0008-5472.22363692
https://doi.org/10.1158/0008-5472.22363692
Autor:
Victoria Plamadeala Johnson, Emanuel Zycband, Stacey Conarello, Yonghua Zhu, David E. Kelley, Michael Staup, Jin Shang, Mark D. Erion, Dan Xie, Keefe Chng, Gladys Arreaza, Stephen F. Previs, Liangsu Wang, Margaret van Heek, Diane Levitan, Yixin Wang, Karni Schlessinger, Sandra C. Souza, Ying Chen, Franklin Liu
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 312:E235-E243
Insulin resistance and diabetes can develop spontaneously with obesity and aging in rhesus monkeys, highly similar to the natural history of obesity, insulin resistance, and progression to type 2 diabetes in humans. The current studies in obese rhesu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea6be096903d99992ef951ec8277fde
https://doi.org/10.1152/ajpendo.00398.2016
https://doi.org/10.1152/ajpendo.00398.2016
Autor:
Effie Tozzo, Eric S. Muise, Yejun Tan, Sandra C. Souza, Karni Schlessinger, John R. Thompson, Liangsu Wang, Franklin Liu, Kevin Liu, Wenyu Li
Publikováno v:
Obesity. 23:1818-1829
Objective Identify a gene expression signature in white adipose tissue (WAT) that reports on WAT browning and is associated with a healthy phenotype. Methods RNA from several different adipose depots across three species were analyzed by whole transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd620e8fe9ecc10d1f32a9804cf20a2e
https://doi.org/10.1002/oby.21153
https://doi.org/10.1002/oby.21153
Autor:
Joanna Wegrzyn, Andrew C. Larner, David E. Levy, Karni Schlessinger, Alicia Corlett, Daniel J. Gough
Publikováno v:
Science. 324:1713-1716
Ras, STAT3, and Transformation The STAT (signal transducer and activator of transcription) proteins are activated in response to receptor stimulation and act in the nucleus to regulate gene expression. Gough et al. (p. 1713 ) found that STAT3 functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b644e0919eaf71cdc0f9d83accf48a4f
https://doi.org/10.1126/science.1171721
https://doi.org/10.1126/science.1171721
Publikováno v:
The Journal of Cell Biology
Scratch-induced disruption of cultured monolayers induces polarity in front row cells that can be visualized by spatially localized polymerization of actin at the front of the cell and reorientation of the centrosome/Golgi to face the leading edge. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff149f72a3fc7c0d8eb317ce6ad25d7
http://europepmc.org/articles/PMC2064837
http://europepmc.org/articles/PMC2064837
Autor:
Karni, Schlessinger, Wenyu, Li, Yejun, Tan, Franklin, Liu, Sandra C, Souza, Effie, Tozzo, Kevin, Liu, John R, Thompson, Liangsu, Wang, Eric S, Muise
Publikováno v:
Obesity (Silver Spring, Md.). 23(9)
Identify a gene expression signature in white adipose tissue (WAT) that reports on WAT browning and is associated with a healthy phenotype.RNA from several different adipose depots across three species were analyzed by whole transcriptome profiling,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5be711d72fe5ced9fb72c867656300c9
https://pubmed.ncbi.nlm.nih.gov/26308478
https://pubmed.ncbi.nlm.nih.gov/26308478
Autor:
A. Brian West, Isabel Novoa, Xiaozhong Wang, Rivka Jungreis, David Ron, Judy H. Cho, Karni Schlessinger, Anne Bertolotti
Publikováno v:
Scopus-Elsevier
The epithelial cells of the gastrointestinal tract are exposed to toxins and infectious agents that can adversely affect protein folding in the endoplasmic reticulum (ER) and cause ER stress. The IRE1 genes are implicated in sensing and responding to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc8a5821b8e233ba7f097e09c204c80
https://doi.org/10.1172/jci11476
https://doi.org/10.1172/jci11476