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Secreted protein profiling of human aortic smooth muscle cells identifies vascular disease associations.

Autor: Aherrahrou R; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America.; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Finland.; Institute for Cardiogenetics, Universität zu Lübeck; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Germany; University Heart Centre Lübeck, Germany., Baig F; King's British Heart Foundation Centre, King's College London, London, United Kingdom., Theofilatos K; King's British Heart Foundation Centre, King's College London, London, United Kingdom., Lue D; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America., Beele A; CVPath Institute, Inc., 19 Firstfield Road, Gaithersburg, MD., Örd T; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Finland., Kaikkonen MU; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Finland., Aherrahrou Z; Institute for Cardiogenetics, Universität zu Lübeck; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Germany; University Heart Centre Lübeck, Germany., Cheng Q; CVPath Institute, Inc., 19 Firstfield Road, Gaithersburg, MD., Ghosh S; CVPath Institute, Inc., 19 Firstfield Road, Gaithersburg, MD., Karnewar S; Department of Molecular Physiology and Biological Physics, Department of Medicine, Division of Cardiology, Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, United States of America., Karnewar V; Department of Molecular Physiology and Biological Physics, Department of Medicine, Division of Cardiology, Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, United States of America., Finn A; CVPath Institute, Inc., 19 Firstfield Road, Gaithersburg, MD., Owens GK; Department of Molecular Physiology and Biological Physics, Department of Medicine, Division of Cardiology, Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, United States of America., Joner M; Klinik für Herz-und Kreislauferkrankungen, Deutsches Herzzentrum München, Technical University Munich, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany., Mayr M; King's British Heart Foundation Centre, King's College London, London, United Kingdom., Civelek M; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America.; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Nov 10. Date of Electronic Publication: 2023 Nov 10.

Treatment of advanced atherosclerotic mice with the senolytic agent ABT-263 is associated with reduced indices of plaque stability and increased mortality.

Autor: Karnewar S; Robert M. Berne Cardiovascular Research Center, University of Virginia-School of Medicine, 415 Lane Road, Suite 1010, Charlottesville, VA, 22908, USA., Karnewar V; Robert M. Berne Cardiovascular Research Center, University of Virginia-School of Medicine, 415 Lane Road, Suite 1010, Charlottesville, VA, 22908, USA., Shankman LS; Robert M. Berne Cardiovascular Research Center, University of Virginia-School of Medicine, 415 Lane Road, Suite 1010, Charlottesville, VA, 22908, USA., Owens GK; Robert M. Berne Cardiovascular Research Center, University of Virginia-School of Medicine, 415 Lane Road, Suite 1010, Charlottesville, VA, 22908, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 13. Date of Electronic Publication: 2023 Jul 13.